Publications by authors named "Kenneth Kosik"

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Controlled-environment platform for electrophysiology recordings on organoids with Neuropixels 2.0.
Zongren Zhang, Tjitse van der Molen, Carolina Maciel Camargo, Markus W Merk, Mookwang Kwon, Kenneth S Kosik

Rev Sci Instrum· December 2025

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Preconfigured neuronal firing sequences in human brain organoids.
Tjitse van der Molen, Alex Spaeth, Mattia Chini, Sebastian Hernandez, Gregory A Kaurala, Kenneth S Kosik

Nat Neurosci· November 2025

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Evolution of the Tri-PDZ Domain in PSD95 (DLG-4 Gene).
Riya Nilkant, Lisa Y Mesrop, Samuel Lobo, Onur Sakarya, Joan E Shea, Kenneth S Kosik

Mol Biol Evol· November 2025

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Case of early onset Alzheimer's disease associated with a novel PSEN1 variant identified in Colombia.
Lina M Zapata-Restrepo, Bruce L Miller, Juan Rivas, Katherine Possin, Victor Valcour, Kenneth S Kosik

NPJ Dement· October 2025

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Protective mechanisms against Alzheimer's disease in APOE3-Christchurch homozygous astrocytes.
Xinran Tian, Erica Keane Rivera, Inyoung Hwang, Arina A Nikitina, Jennifer A Smith, Kenneth S Kosik

Alzheimers Dement· September 2025

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Structure-specific Mini-Prion Model for Alzheimer's Disease Tau Fibrils.
Vishnu Vijayan, Gregory E Merz, Karen Tsay, Andrew P Longhini, Samuel Lobo, Kenneth S Kosik

bioRxiv· June 2025

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Water-directed pinning is key to tau prion formation.
Michael P Vigers, Samuel Lobo, Saeed Najafi, Austin Dubose, Karen Tsay, Kenneth S Kosik

Proc Natl Acad Sci U S A· May 2025

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Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.
Juliana Acosta-Uribe, Stefanie D Piña Escudero, J Nicholas Cochran, Jared W Taylor, P Alejandra Castruita, Kenneth S Kosik

Res Sq· May 2025

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Geometry based prediction of tau protein sites and motifs associated with misfolding and aggregation.
Masumi Sugiyama, Kenneth S Kosik, Eleni Panagiotou

Sci Rep· March 2025

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Driving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity.
Yakeel T Quiroz, David Aguillón, Joseph Arboleda-Velasquez, Yamile Bocanegra, Gloria Patricia Cardona-Gómez, Kenneth Kosik

Alzheimers Dement· March 2025

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Comorbidities in early-onset sporadic versus presenilin-1 mutation-associated Alzheimer disease dementia: Evidence for dependency on Alzheimer disease neuropathological changes.
Diego Sepulveda-Falla, Carlos Andrés Villegas Lanau, Charles White Iii, Geidy E Serrano, Juliana Acosta-Uribe, Kenneth S Kosik

J Neuropathol Exp Neurol· February 2025

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Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations.
Sebastian Moguilner, Sandra Baez, Hernan Hernandez, Joaquín Migeot, Agustina Legaz, Kenneth S Kosik

Nat Med· December 2024

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Author Correction: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations.
Sebastian Moguilner, Sandra Baez, Hernan Hernandez, Joaquín Migeot, Agustina Legaz, Kenneth S Kosik

Nat Med· December 2024

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RT-Sort: An action potential propagation-based algorithm for real time spike detection and sorting with millisecond latencies.
Tjitse van der Molen, Max Lim, Julian Bartram, Zhuowei Cheng, Ash Robbins, Kenneth S Kosik

PLoS One· December 2024

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Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.
Juliana Acosta-Uribe, Stefanie D Piña Escudero, J Nicholas Cochran, Jared W Taylor, P Alejandra Castruita, Kenneth S Kosik

medRxiv· November 2024

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Impact of APOE ε4 and ε2 on plasma neurofilament light chain and cognition in autosomal dominant Alzheimer's disease.
Stephanie Langella, Kyra Bonta, Yinghua Chen, Yi Su, Daniel Vasquez, Kenneth S Kosik

Alzheimers Res Ther· October 2024

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Primary lateral sclerosis associated with PSEN1 Pro284Leu variant in a Colombian family: Clinical and neuropathological features.
Juliana Acosta-Uribe, Andrés Villegas-Lanau, Dionis Vallejo, Laura Ramírez-Aguilar, Juan M Solano, Kenneth S Kosik

Alzheimers Dement· September 2024

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Global Challenges After a Global Challenge: Lessons Learned from the COVID-19 Pandemic.
Niloufar Yazdanpanah, Constantine Sedikides, Hans D Ochs, Carlos A Camargo, Gary L Darmstadt, Kenneth S Kosik

Adv Exp Med Biol· September 2024

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Why brain organoids are not conscious yet.
Kenneth S Kosik

Patterns (N Y)· August 2024

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Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer's disease profile and possible mechanisms of disease protection.
Maria Camila Almeida, Sarah J Eger, Caroline He, Morgane Audouard, Arina Nikitina, Kenneth S Kosik

Neuron· June 2024

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Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease.
Yakeel T Quiroz, David Aguillon, Daniel C Aguirre-Acevedo, Daniel Vasquez, Yesica Zuluaga, Kenneth S Kosik

N Engl J Med· June 2024

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Brain clocks capture diversity and disparity in aging and dementia.
Sebastian Moguilner, Sandra Baez, Hernan Hernandez, Joaquín Migeot, Agustina Legaz, Kenneth S Kosik

Res Sq· June 2024

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Testing the Conjecture That Quantum Processes Create Conscious Experience.
Hartmut Neven, Adam Zalcman, Peter Read, Kenneth S Kosik, Tjitse van der Molen

Entropy (Basel)· May 2024

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Precision proteoform design for 4R tau isoform selective templated aggregation.
Andrew P Longhini, Austin DuBose, Samuel Lobo, Vishnu Vijayan, Yeran Bai, Kenneth S Kosik

Proc Natl Acad Sci U S A· April 2024

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Mathematical topology and geometry-based classification of tauopathies.
Masumi Sugiyama, Kenneth S Kosik, Eleni Panagiotou

Sci Rep· March 2024

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