Publications by authors named "Kenneth L Scott"

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Simultaneous screening of overexpressed genes in breast cancer for oncogenic drivers and tumor dependencies.
Adaobi Mofunanya, Eleanor R Cameron, Christian J Braun, Frank Celeste, Xiaoyu Zhao, Kenneth L Scott, Scott Powers

Sci Rep· June 2024

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In vivo functional characterization of EGFR variants identifies novel drivers of glioblastoma.
Kwanha Yu, Kathleen Kong, Brittney Lozzi, Estefania Luna-Figueroa, Alexis Cervantes, Kenneth L Scott

Neuro Oncol· March 2023

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A functional genomic approach to actionable gene fusions for precision oncology.
Jun Li, Hengyu Lu, Patrick Kwok-Shing Ng, Angeliki Pantazi, Carman Ka Man Ip, Kenneth L Scott

Sci Adv· February 2022

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POT1 Regulates Proliferation and Confers Sexual Dimorphism in Glioma.
Ali Jalali, Kwanha Yu, Vivek Beechar, Navish A Bosquez Huerta, Anthony Grichuk, Kenneth L Scott

Cancer Res· May 2021

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IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion.
Rakhee Bajaj, Samrat T Kundu, Caitlin L Grzeskowiak, Jared J Fradette, Kenneth L Scott

Oncogene· September 2020

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Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression.
Yiu Huen Tsang, Yumeng Wang, Kathleen Kong, Caitlin Grzeskowiak, Oksana Zagorodna, Kenneth L Scott

Elife· April 2020

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PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis.
Kwanha Yu, Chia-Ching John Lin, Asante Hatcher, Brittney Lozzi, Kathleen Kong, Kenneth L Scott

Nature· February 2020

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PI4KIIIβ is a therapeutic target in chromosome 1q-amplified lung adenocarcinoma.
Xiaochao Tan, Priyam Banerjee, Edward A Pham, Florentine U N Rutaganira, Kaustabh Basu, Kenneth L Scott

Sci Transl Med· January 2020

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The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing.
Xiaohui Hu, Samuel E Harvey, Rong Zheng, Jingyi Lyu, Caitlin L Grzeskowiak, Kenneth L Scott

Nat Commun· January 2020

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Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage.
Jun Xia, Li-Ya Chiu, Ralf B Nehring, María Angélica Bravo Núñez, Qian Mei, Kenneth L Scott

Cell· January 2019

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Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies.
Carman K M Ip, Patrick K S Ng, Kang Jin Jeong, S H Shao, Zhenlin Ju, Kenneth L Scott

Nat Commun· November 2018

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Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2.
Byung-Kwon Choi, Tajhal Dayaram, Neha Parikh, Angela D Wilkins, Meena Nagarajan, Kenneth L Scott, Scott Spangler

Proc Natl Acad Sci U S A· October 2018

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RNA editing derived epitopes function as cancer antigens to elicit immune responses.
Minying Zhang, Jens Fritsche, Jason Roszik, Leila J Williams, Xinxin Peng, Kenneth L Scott

Nat Commun· September 2018

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Cancer driver mutation prediction through Bayesian integration of multi-omic data.
Zixing Wang, Kwok-Shing Ng, Tenghui Chen, Tae-Beom Kim, Fang Wang, Kenneth L Scott

PLoS One· August 2018

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In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.
Caitlin L Grzeskowiak, Samrat T Kundu, Xiulei Mo, Andrei A Ivanov, Oksana Zagorodna, Kenneth L Scott

Nat Commun· July 2018

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TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.
Samrat T Kundu, Caitlin L Grzeskowiak, Jared J Fradette, Laura A Gibson, Leticia B Rodriguez, Kenneth L Scott

Nat Commun· July 2018

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The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.
Xiaochao Tan, Priyam Banerjee, Xin Liu, Jiang Yu, Don L Gibbons, Kenneth L Scott

J Clin Invest· July 2018

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Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer.
Amritha Nair, Hsiang-Ching Chung, Tingting Sun, Siddhartha Tyagi, Lacey E Dobrolecki, Kenneth L Scott

Nat Med· May 2018

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A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.
Xinxin Peng, Xiaoyan Xu, Yumeng Wang, David H Hawke, Shuangxing Yu, Kenneth L Scott

Cancer Cell· May 2018

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The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.
Xiaochao Tan, Priyam Banerjee, Xin Liu, Jiang Yu, Don L Gibbons, Kenneth L Scott

J Clin Invest· April 2018

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A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis.
Emily Powell, Jiansu Shao, Hector M Picon, Christopher Bristow, Zhongqi Ge, Kenneth L Scott

NPJ Breast Cancer· April 2018

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Systematic Functional Annotation of Somatic Mutations in Cancer.
Patrick Kwok-Shing Ng, Jun Li, Kang Jin Jeong, Shan Shao, Hu Chen, Kenneth L Scott

Cancer Cell· March 2018

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Differential UBE2C and HOXA1 expression in melanocytic nevi and melanoma.
Stefan Kraft, Johanna B Moore, Alona Muzikansky, Kenneth L Scott, Lyn M Duncan

J Cutan Pathol· October 2017

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Daam2 driven degradation of VHL promotes gliomagenesis.
Wenyi Zhu, Saritha Krishna, Cristina Garcia, Chia-Ching John Lin, Bartley D Mitchell, Kenneth L Scott

Elife· October 2017

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Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in mutant cancers.
Chaoyang Sun, Yong Fang, Jun Yin, Jian Chen, Zhenlin Ju, Kenneth L Scott

Sci Transl Med· May 2017

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