Publications by authors named "Kenneth Lloyd"

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Plinabulin following radiation enhances dendritic cell maturation and checkpoint inhibitor retreatment of relapsed/refractory cancers.
Steven H Lin, Vivek Subbiah, Shinya Neri, Evan N Cohen, Ziyi Li, G Kenneth Lloyd

Med· October 2025

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Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits.
Yuxin Hao, Jiabin Yan, Courtney Fraser, Aiping Jiang, Murali Anuganti, Kenneth Lloyd

MAbs· June 2024

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High-Throughput Protein Expression Screening of Cell-Surface Protein Ectodomains.
Anita Ghosh, Chang Yang, Kenneth Lloyd, Rob Meijers

Methods Mol Biol· June 2024

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CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness.
Xiaodan Qin, Andrew Lam, Xu Zhang, Satyaki Sengupta, J Bryan Iorgulescu, Kenneth Lloyd

Sci Adv· March 2024

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Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits.
Yuxin Hao, Jiabin Yan, Courtney Fraser, Aiping Jiang, Murali Anuganti, Kenneth Lloyd

bioRxiv· January 2024

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Plinabulin, a Distinct Microtubule-Targeting Chemotherapy, Promotes M1-Like Macrophage Polarization and Anti-tumor Immunity.
Marina Natoli, Petra Herzig, Elham Pishali Bejestani, Melanie Buchi, Reto Ritschard, G Kenneth Lloyd

Front Oncol· March 2021

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Plinabulin ameliorates neutropenia induced by multiple chemotherapies through a mechanism distinct from G-CSF therapies.
James R Tonra, G Kenneth Lloyd, Ramon Mohanlal, Lan Huang

Cancer Chemother Pharmacol· February 2020

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Plinabulin, an inhibitor of tubulin polymerization, targets KRAS signaling through disruption of endosomal recycling.
Patrick J Cimino, Lan Huang, Lihua Du, Yanping Wu, Jamie Bishop, G Kenneth Lloyd

Biomed Rep· April 2019

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Red wine and green tea flavonoids are -allosteric activators and competitive inhibitors of glucose transporter 1 (GLUT1)-mediated sugar uptake.
Ogooluwa A Ojelabi, Kenneth P Lloyd, Julie K De Zutter, Anthony Carruthers

J Biol Chem· December 2018

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Kinetic Basis of Cis- and Trans-Allostery in GLUT1-Mediated Sugar Transport.
Kenneth P Lloyd, Ogooluwa A Ojelabi, Andrew H Simon, Julie K De Zutter, Anthony Carruthers

J Membr Biol· February 2018

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Reconciling contradictory findings: Glucose transporter 1 (GLUT1) functions as an oligomer of allosteric, alternating access transporters.
Kenneth P Lloyd, Ogooluwa A Ojelabi, Julie K De Zutter, Anthony Carruthers

J Biol Chem· December 2017

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WZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site.
Ogooluwa A Ojelabi, Kenneth P Lloyd, Andrew H Simon, Julie K De Zutter, Anthony Carruthers

J Biol Chem· December 2016

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Marizomib activity as a single agent in malignant gliomas: ability to cross the blood-brain barrier.
Kaijun Di, G Kenneth Lloyd, Vivek Abraham, Ann MacLaren, Francis J Burrows

Neuro Oncol· June 2016

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Caffeine inhibits glucose transport by binding at the GLUT1 nucleotide-binding site.
Jay M Sage, Anthony J Cura, Kenneth P Lloyd, Anthony Carruthers

Am J Physiol Cell Physiol· May 2015

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Phase 1 clinical trial of the novel proteasome inhibitor marizomib with the histone deacetylase inhibitor vorinostat in patients with melanoma, pancreatic and lung cancer based on in vitro assessments of the combination.
Michael Millward, Timothy Price, Amanda Townsend, Christopher Sweeney, Andrew Spencer, G Kenneth Lloyd

Invest New Drugs· December 2012

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Vascular effects of plinabulin (NPI-2358) and the influence on tumour response when given alone or combined with radiation.
Lotte B Bertelsen, Yuan Yuan Shen, Thomas Nielsen, Hans Stødkilde-Jørgensen, G Kenneth Lloyd

Int J Radiat Biol· November 2011

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Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogs.
Amanda Obaidat, Jeffrey Weiss, Brett Wahlgren, Rama R Manam, Venkat R Macherla, G Kenneth Lloyd

J Pharmacol Exp Ther· May 2011

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Phase 1 first-in-human trial of the vascular disrupting agent plinabulin(NPI-2358) in patients with solid tumors or lymphomas.
Monica M Mita, Matthew A Spear, Lorrin K Yee, Alain C Mita, Elisabeth I Heath, G Kenneth Lloyd

Clin Cancer Res· December 2010

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The current treatment of pulmonary hypertension.
Kenneth Scott Lloyd

Methodist Debakey Cardiovasc J· March 2010

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Portability of the GN(R)A hairpin loop motif between RNA and DNA.
Joshua M Blose, Kenneth P Lloyd, Philip C Bevilacqua

Biochemistry· September 2009

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Synthesis of biotin-tagged diketopiperazine-based anti-microtubule agents and tubulin photoaffinity labeling.
Yuri Yamazaki, Kyoko Kohno, Hiroyuki Yasui, Yoshiaki Kiso, Saskia Neuteboom, G Kenneth Lloyd

Adv Exp Med Biol· June 2009

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Development of pharmacotherapies for drug addiction: a Rosetta stone approach.
George F Koob, G Kenneth Lloyd, Barbara J Mason

Nat Rev Drug Discov· June 2009

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Discovery and development of the anticancer agent salinosporamide A (NPI-0052).
William Fenical, Paul R Jensen, Michael A Palladino, Kin S Lam, G Kenneth Lloyd

Bioorg Med Chem· March 2009

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Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents.
Yuri Yamazaki, Kyoko Kohno, Hiroyuki Yasui, Yoshiaki Kiso, Miki Akamatsu, G Kenneth Lloyd

Chembiochem· December 2008

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Leaving groups prolong the duration of 20S proteasome inhibition and enhance the potency of salinosporamides.
Rama Rao Manam, Katherine A McArthur, Ta-Hsiang Chao, Jeffrey Weiss, Janid A Ali, G Kenneth Lloyd

J Med Chem· November 2008

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