Publications by authors named "Kenneth Paigen"

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Variation in histone configurations correlates with gene expression across nine inbred strains of mice.
Anna L Tyler, Catrina Spruce, Romy Kursawe, Annat Haber, Robyn L Ball, Kenneth Paigen

Genome Res· June 2023

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Differential effects of two catalytic mutations on full-length PRDM9 and its isolated PR/SET domain reveal a case of pseudomodularity.
Natalie R Powers, Timothy Billings, Kenneth Paigen, Petko M Petkov

Genetics· December 2021

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Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard.
Natalie R Powers, Beth L Dumont, Chihiro Emori, Raman Akinyanju Lawal, Catherine Brunton, Kenneth Paigen

Sci Adv· October 2020

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HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hot spots.
Catrina Spruce, Sibongakonke Dlamini, Guruprasad Ananda, Naomi Bronkema, Hui Tian, Kenneth Paigen

Genes Dev· March 2020

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Histone methyltransferase PRDM9 is not essential for meiosis in male mice.
Ondrej Mihola, Florencia Pratto, Kevin Brick, Eliska Linhartova, Tatyana Kobets, Kenneth Paigen

Genome Res· July 2019

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Tissue-Specific Regulation of the Mouse Epigenome.
Christopher L Baker, Michael Walker, Seda Arat, Guruprasad Ananda, Pavlina Petkova, Kenneth Paigen

Genetics· March 2019

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PRDM9 and Its Role in Genetic Recombination.
Kenneth Paigen, Petko M Petkov

Trends Genet· April 2018

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PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis.
Emil D Parvanov, Hui Tian, Timothy Billings, Ruth L Saxl, Catrina Spruce, Kenneth Paigen

Mol Biol Cell· February 2017

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The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo.
Natalie R Powers, Emil D Parvanov, Christopher L Baker, Michael Walker, Petko M Petkov, Kenneth Paigen

PLoS Genet· June 2016

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Health and population effects of rare gene knockouts in adult humans with related parents.
Vagheesh M Narasimhan, Karen A Hunt, Dan Mason, Christopher L Baker, Konrad J Karczewski, Kenneth Paigen

Science· April 2016

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Nuclear localization of PRDM9 and its role in meiotic chromatin modifications and homologous synapsis.
Fengyun Sun, Yasuhiro Fujiwara, Laura G Reinholdt, Jianjun Hu, Ruth L Saxl, Kenneth Paigen

Chromosoma· September 2015

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Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage.
Michael Walker, Timothy Billings, Christopher L Baker, Natalie Powers, Hui Tian, Kenneth Paigen

Epigenetics Chromatin· September 2015

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Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots.
Christopher L Baker, Pavlina Petkova, Michael Walker, Petr Flachs, Ondrej Mihola, Kenneth Paigen

PLoS Genet· September 2015

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A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.
John P Didion, Andrew P Morgan, Amelia M-F Clayshulte, Rachel C Mcmullan, Liran Yadgary, Kenneth Paigen

PLoS Genet· February 2015

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PRDM9 drives evolutionary erosion of hotspots in Mus musculus through haplotype-specific initiation of meiotic recombination.
Christopher L Baker, Shimpei Kajita, Michael Walker, Ruth L Saxl, Narayanan Raghupathy, Kenneth Paigen

PLoS Genet· January 2015

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PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration.
Christopher L Baker, Michael Walker, Shimpei Kajita, Petko M Petkov, Kenneth Paigen

Genome Res· May 2014

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DNA binding specificities of the long zinc-finger recombination protein PRDM9.
Timothy Billings, Emil D Parvanov, Christopher L Baker, Michael Walker, Kenneth Paigen

Genome Biol· April 2013

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Meiotic DSBs and the control of mammalian recombination.
Kenneth Paigen, Petko Petkov

Cell Res· December 2012

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Clusters of ancestrally related genes that show paralogy in whole or in part are a major feature of the genomes of humans and other species.
Michael B Walker, Benjamin L King, Kenneth Paigen

PLoS One· September 2012

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Mammalian recombination hot spots: properties, control and evolution.
Kenneth Paigen, Petko Petkov

Nat Rev Genet· March 2010

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Prdm9 controls activation of mammalian recombination hotspots.
Emil D Parvanov, Petko M Petkov, Kenneth Paigen

Science· February 2010

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Colocalization of somatic and meiotic double strand breaks near the Myc oncogene on mouse chromosome 15.
Siemon H Ng, Sarah A Maas, Petko M Petkov, Kevin D Mills, Kenneth Paigen

Genes Chromosomes Cancer· October 2009

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Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans.
Alison H Harrill, Paul B Watkins, Stephen Su, Pamela K Ross, David E Harbourt, Kenneth Paigen

Genome Res· September 2009

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Parental origin of chromosomes influences crossover activity within the Kcnq1 transcriptionally imprinted domain of Mus musculus.
Siemon H Ng, Rose Madeira, Emil D Parvanov, Lorin M Petros, Petko M Petkov, Kenneth Paigen

BMC Mol Biol· May 2009

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Trans-regulation of mouse meiotic recombination hotspots by Rcr1.
Emil D Parvanov, Siemon H S Ng, Petko M Petkov, Kenneth Paigen

PLoS Biol· February 2009

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