Publications by authors named "Kenneth R Pryde"

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The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors.
Rachel E Hardy, Injae Chung, Yizhou Yu, Samantha H Y Loh, Nobuhiro Morone, Kenneth R Pryde

Biol Direct· August 2023

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Cell Morphological Profiling Enables High-Throughput Screening for PROteolysis TArgeting Chimera (PROTAC) Phenotypic Signature.
Maria-Anna Trapotsi, Elizabeth Mouchet, Guy Williams, Tiziana Monteverde, Karolina Juhani, Kenneth R Pryde

ACS Chem Biol· July 2022

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Identification of a novel toxicophore in anti-cancer chemotherapeutics that targets mitochondrial respiratory complex I.
Zoe A Stephenson, Robert F Harvey, Kenneth R Pryde, Sarah Mistry, Rachel E Hardy

Elife· May 2020

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A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.
Kenneth Robert Pryde, Jan Willem Taanman, Anthony Henry Schapira

Cell Rep· December 2016

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PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy.
Kenneth R Pryde, Heather L Smith, Kai-Yin Chau, Anthony H V Schapira

J Cell Biol· April 2016

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Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer.
Kenneth R Pryde, Judy Hirst

J Biol Chem· May 2011

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The production of reactive oxygen species by complex I.
Judy Hirst, Martin S King, Kenneth R Pryde

Biochem Soc Trans· October 2008

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A comparative cell biological analysis reveals only limited functional homology between the NS5A proteins of hepatitis C virus and GB virus B.
Jamel Mankouri, Andrew Milward, Kenneth R Pryde, Lucile Warter, Annette Martin

J Gen Virol· August 2008

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