Publications by authors named "Kensuke Okuda"

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Elucidation of the acid reactivity of polyhedral orthoformates for the synthesis of carbasugar derivatives.
Kazuki Usuguchi, Akira Takagi, Ippei Takashima, Kensuke Okuda

RSC Adv· June 2025

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Total Synthesis of Antiausterity Agent Callistrilone O Reveals Promising Antitumor Activity in a Melanoma Homograft Mouse Model.
Kensuke Okuda, Akira Takagi, Ryohei Shimizu, Kensuke Nishi, Narumi Hayano

ChemMedChem· April 2025

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A turn-on fluorescent probe containing a β-ketoester moiety for the selective detection of intracellular hydrazine.
Akira Takagi, Ippei Takashima, Kensuke Okuda

RSC Adv· January 2025

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Pilot-scale performance of gravity-driven ultra-high flux fabric membrane systems for removing small-sized microplastics in wastewater treatment plant effluents.
Ibukun Oluwoye, Shuhei Tanaka, Kensuke Okuda

J Environ Manage· July 2024

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Development of 1,3,6-Tribenzoylated Glucose as an Antiausterity Agent Targeting Tumor Microenvironment.
Akira Takagi, Kazuki Usuguchi, Ippei Takashima, Kensuke Okuda

Chem Pharm Bull (Tokyo)· August 2023

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Advances in reaction-based synthetic fluorescent probes for studying the role of zinc and copper ions in living systems.
Kensuke Okuda, Ippei Takashima, Akira Takagi

J Clin Biochem Nutr· January 2023

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Extracts of induce growth inhibition and changes in the protein expression of cell cycle control molecules in human colorectal cancer cell lines.
Harutoshi Matsumoto, Saeko Ando, Eri Yoshimoto, Takamasa Numano, Nahida Sultana, Kensuke Okuda

Oncol Lett· March 2022

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Total Synthesis of Antiausterity Agent (±)-Uvaridacol L by Regioselective Axial Diacylation of a -Inositol Orthoester.
Akira Takagi, Kazuki Usuguchi, Ippei Takashima, Kensuke Okuda

Org Lett· June 2021

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Development of antitumor biguanides targeting energy metabolism and stress responses in the tumor microenvironment.
Takayuki Sakai, Yoshiyuki Matsuo, Kensuke Okuda, Kiichi Hirota, Mieko Tsuji

Sci Rep· March 2021

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A fluorogenic probe using a catalytic reaction for the detection of trace intracellular zinc.
Ippei Takashima, Yohei Inoue, Nobuyuki Matsumoto, Akira Takagi, Kensuke Okuda

Chem Commun (Camb)· November 2020

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Hydrogen sulfide increases copper-dependent neurotoxicity via intracellular copper accumulation.
Norika Goto, Hirokazu Hara, Mao Kondo, Naomi Yasuda, Tetsuro Kamiya, Kensuke Okuda

Metallomics· June 2020

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Effects of 2-(2-Chlorophenyl)ethylbiguanide on ERAD Component Expression in HT-29 Cells Under a Serum- and Glucose-Deprived Condition.
Kentaro Oh-Hashi, Shiori Matsumoto, Takayuki Sakai, Yoko Hirata, Kensuke Okuda

Appl Biochem Biotechnol· August 2019

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Elucidating the rapid action of 2-(2-chlorophenyl)ethylbiguanide on HT-29 cells under a serum- and glucose-deprived condition.
Kentaro Oh-Hashi, Shiori Matsumoto, Takayuki Sakai, Yuki Nomura, Kensuke Okuda

Cell Biol Toxicol· August 2018

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Hydrogen sulfide ameliorates zinc-induced cell death in neuroblastoma SH-SY5Y cells.
Megumi Shimoji, Hirokazu Hara, Tetsuro Kamiya, Kensuke Okuda, Tetsuo Adachi

Free Radic Res· December 2017

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Bismuth-rhodamine: a new red light-excitable photosensitizer.
Tasuku Hirayama, Akari Mukaimine, Kenta Nishigaki, Hitomi Tsuboi, Shusaku Hirosawa, Kensuke Okuda

Dalton Trans· November 2017

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A universal fluorogenic switch for Fe(ii) ion based on N-oxide chemistry permits the visualization of intracellular redox equilibrium shift towards labile iron in hypoxic tumor cells.
Tasuku Hirayama, Hitomi Tsuboi, Masato Niwa, Ayaji Miki, Satoki Kadota, Kensuke Okuda

Chem Sci· July 2017

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In vivo retinal and choroidal hypoxia imaging using a novel activatable hypoxia-selective near-infrared fluorescent probe.
Shinichi Fukuda, Kensuke Okuda, Genichiro Kishino, Sujin Hoshi, Itsuki Kawano

Graefes Arch Clin Exp Ophthalmol· December 2016

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Elucidation of a novel phenformin derivative on glucose-deprived stress responses in HT-29 cells.
Kentaro Oh-Hashi, Nao Irie, Takayuki Sakai, Kensuke Okuda, Hideko Nagasawa

Mol Cell Biochem· August 2016

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Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment.
Kosuke Narise, Kensuke Okuda, Yukihiro Enomoto, Tasuku Hirayama, Hideko Nagasawa

Drug Des Devel Ther· April 2016

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Solution-phase synthesis and biological evaluation of triostin A and its analogues.
Kozo Hattori, Kota Koike, Kensuke Okuda, Tasuku Hirayama, Masahiro Ebihara

Org Biomol Chem· February 2016

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A highly sensitive assay of IRE1 activity using the small luciferase NanoLuc: Evaluation of ALS-related genetic and pathological factors.
Takahiro Hikiji, Junpei Norisada, Yoko Hirata, Kensuke Okuda, Hideko Nagasawa

Biochem Biophys Res Commun· August 2015

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A new class of high-contrast Fe(II) selective fluorescent probes based on spirocyclized scaffolds for visualization of intracellular labile iron delivered by transferrin.
Masato Niwa, Tasuku Hirayama, Kensuke Okuda, Hideko Nagasawa

Org Biomol Chem· September 2014

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Facile one-pot synthesis of [1, 2, 3]triazolo[1, 5-a]pyridines from 2-acylpyridines by copper(II)-catalyzed oxidative N-N bond formation.
Tasuku Hirayama, Satoshi Ueda, Takahiro Okada, Norihiko Tsurue, Kensuke Okuda

Chemistry· April 2014

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FRET-based imaging of transbilayer movement of pepducin in living cells by novel intracellular bioreductively activatable fluorescent probes.
Mieko Tsuji, Satoshi Ueda, Tasuku Hirayama, Kensuke Okuda, Yoshiaki Sakaguchi

Org Biomol Chem· May 2013

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10'-Chloro-3',4'-dihydro-2'H-spiro-[cyclo-propane-1,7'(6'H)-pyrimido[2,1-a]isoquinolin]-6'-one.
Kensuke Okuda, Takashi Hirota, Yuta Nishina, Hiroyuki Ishida

Acta Crystallogr Sect E Struct Rep Online· November 2012

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