Publications by authors named "Kent Sakai"

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IL-33 Sensitizes Mast Cells to PIEZO1 Stimulation Leading to Degranulation.
Yoshiaki Kobayashi, Kent Sakai, Nguyen Quoc Vuong Tran, Kayoko Ishimaru, Takuya Sato

Allergy· December 2024

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Microglia sense astrocyte dysfunction and prevent disease progression in an Alexander disease model.
Kozo Saito, Eiji Shigetomi, Youichi Shinozaki, Kenji Kobayashi, Bijay Parajuli, Kent Sakai

Brain· February 2024

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Extracellular ATP/adenosine dynamics in the brain and its role in health and disease.
Eiji Shigetomi, Kent Sakai, Schuichi Koizumi

Front Cell Dev Biol· January 2024

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Severity of Peripheral Infection Differentially Affects Brain Functions in Mice via Microglia-Dependent and -Independent Mechanisms.
Yen-Phung Le, Kozo Saito, Bijay Parajuli, Kent Sakai, Yuto Kubota

Int J Mol Sci· December 2023

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Dynorphinergic Projections from the Central Amygdala to the Parabrachial Nucleus Regulate Itch.
Hideki Funahashi, Darya Pavlenko, Kent Sakai, Rebecca Verpile, Kristen M Sanders

J Neurosci· July 2023

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IL-23 modulates histamine-evoked itch and responses of pruriceptors in mice.
Darya Pavlenko, Hideki Funahashi, Kent Sakai, Takashi Hashimoto, Taisa Lozada

Exp Dermatol· December 2020

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Low-Threshold Mechanosensitive VGLUT3-Lineage Sensory Neurons Mediate Spinal Inhibition of Itch by Touch.
Kent Sakai, Kristen M Sanders, Shing-Hong Lin, Darya Pavlenko, Hideki Funahashi

J Neurosci· September 2020

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Peripheral circadian rhythms in the liver and white adipose tissue of mice are attenuated by constant light and restored by time-restricted feeding.
Daisuke Yamamuro, Manabu Takahashi, Shuichi Nagashima, Tetsuji Wakabayashi, Hisataka Yamazaki, Kent Sakai

PLoS One· August 2020

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New insights into the mechanisms behind mechanical itch.
Kent Sakai, Tasuku Akiyama

Exp Dermatol· August 2020

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Signal Transducer and Activator of Transcription 3 in Keratinocytes Regulates Histaminergic Itch but Not Nonhistaminergic Itch.
Takashi Hashimoto, Kent Sakai, Gil Yosipovitch, Tasuku Akiyama

Acta Derm Venereol· September 2019

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Disinhibition of Touch-Evoked Itch in a Mouse Model of Psoriasis.
Kent Sakai, Tasuku Akiyama

J Invest Dermatol· June 2019

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A Subpopulation of Amygdala Neurons Mediates the Affective Component of Itch.
Kristen M Sanders, Kent Sakai, Tyler D Henry, Takashi Hashimoto, Tasuku Akiyama

J Neurosci· April 2019

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Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells.
Hisataka Yamazaki, Manabu Takahashi, Tetsuji Wakabayashi, Kent Sakai, Daisuke Yamamuro

J Atheroscler Thromb· March 2019

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Antipruritic Effects of Janus Kinase Inhibitor Tofacitinib in a Mouse Model of Psoriasis.
Takashi Hashimoto, Kent Sakai, Kristen M Sanders, Gil Yosipovitch, Tasuku Akiyama

Acta Derm Venereol· March 2019

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Myeloid HMG-CoA (3-Hydroxy-3-Methylglutaryl-Coenzyme A) Reductase Determines Atherosclerosis by Modulating Migration of Macrophages.
Kent Sakai, Shuichi Nagashima, Tetsuji Wakabayashi, Bayasgalan Tumenbayar, Hiroko Hayakawa

Arterioscler Thromb Vasc Biol· November 2018

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Modulation of Itch by Localized Skin Warming and Cooling.
Kristen M Sanders, Takashi Hashimoto, Kent Sakai, Tasuku Akiyama

Acta Derm Venereol· October 2018

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Role of neurturin in spontaneous itch and increased nonpeptidergic intraepidermal fiber density in a mouse model of psoriasis.
Kent Sakai, Kristen M Sanders, Marina R Youssef, Kevin M Yanushefski, Liselotte E Jensen

Pain· November 2017

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Expression of Histidine Decarboxylase in the Epidermis of Primates with Chronic Itch.
Yoshihiro Inami, Leigh Ann Nattkemper, Kent Sakai, Gil Yosipovitch, Tasuku Akiyama

Acta Derm Venereol· June 2017

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Mouse model of imiquimod-induced psoriatic itch.
Kent Sakai, Kristen M Sanders, Marina R Youssef, Kevin M Yanushefski, Liselotte Jensen

Pain· November 2016

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Plasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liver.
Shuichi Nagashima, Hiroaki Yagyu, Ryuichi Tozawa, Fumiko Tazoe, Manabu Takahashi, Kent Sakai

J Lipid Res· May 2015

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Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages.
Kent Sakai, Masaki Igarashi, Daisuke Yamamuro, Taichi Ohshiro, Shuichi Nagashima

J Lipid Res· October 2014

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Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages.
Motohiro Sekiya, Daisuke Yamamuro, Taichi Ohshiro, Akira Honda, Manabu Takahashi, Kent Sakai

J Lipid Res· October 2014

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Search method for inhibitors of Staphyloxanthin production by methicillin-resistant Staphylococcus aureus.
Kent Sakai, Nobuhiro Koyama, Takashi Fukuda, Yukiko Mori, Hiroyasu Onaka

Biol Pharm Bull· June 2012

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Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia.
Taichi Ohshiro, Daisuke Matsuda, Kent Sakai, Chiara Degirolamo, Hiroaki Yagyu

Arterioscler Thromb Vasc Biol· May 2011

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Selective inhibition of acyl-CoA:cholesterol acyltransferase 2 isozyme by flavasperone and sterigmatocystin from Aspergillus species.
Kent Sakai, Satoshi Ohte, Taichi Ohshiro, Daisuke Matsuda, Rokuro Masuma

J Antibiot (Tokyo)· September 2008

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