Publications by authors named "Kentaro Handa"

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Correction to "An Updated Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Concentrations after Oral Doses in Rats".
Yusuke Kamiya, Kentaro Handa, Tomonori Miura, Junya Ohori, Makiko Shimizu

Chem Res Toxicol· August 2022

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Machine Learning Prediction of the Three Main Input Parameters of a Simplified Physiologically Based Pharmacokinetic Model Subsequently Used to Generate Time-Dependent Plasma Concentration Data in Humans after Oral Doses of 212 Disparate Chemicals.
Yusuke Kamiya, Kentaro Handa, Tomonori Miura, Junya Ohori, Airi Kato

Biol Pharm Bull· January 2022

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Prediction of permeability across intestinal cell monolayers for 219 disparate chemicals using in vitro experimental coefficients in a pH gradient system and in silico analyses by trivariate linear regressions and machine learning.
Yusuke Kamiya, Asuka Omura, Riku Hayasaka, Rie Saito, Izumi Sano, Kentaro Handa

Biochem Pharmacol· October 2021

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An Updated Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Concentrations after Oral Doses in Rats.
Yusuke Kamiya, Kentaro Handa, Tomonori Miura, Junya Ohori, Makiko Shimizu

Chem Res Toxicol· October 2021

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Prediction Models for Agonists and Antagonists of Molecular Initiation Events for Toxicity Pathways Using an Improved Deep-Learning-Based Quantitative Structure-Activity Relationship System.
Yasunari Matsuzaka, Shin Totoki, Kentaro Handa, Tetsuyoshi Shiota, Kota Kurosaki

Int J Mol Sci· October 2021

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Prediction of Input Parameters for Simplified Physiologically Based Pharmacokinetic Models for Estimating Plasma, Liver, and Kidney Exposures in Rats after Oral Doses of 246 Disparate Chemicals.
Yusuke Kamiya, Kentaro Handa, Tomonori Miura, Mayu Yanagi, Kazuki Shigeta

Chem Res Toxicol· February 2021

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