Publications by authors named "Kequan Lin"

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Heat shock protein DNAJA2 controls insulin signaling and glucose homeostasis by preventing spontaneous insulin receptor endocytosis.
Yuanhua Qin, Wenjun Wu, Kequan Lin, Anthony J Davis, Yaping Huang

Nat Commun· November 2025

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Gene Signature-Based Drug Screening Reveals Ponatinib Enhances Immunotherapy Efficacy in Triple-Negative Breast Cancer by Reversing MDSC-Mediated Immunosuppressive Tumor Microenvironment.
Qianyu Wang, Shasha Li, Yuan Wu, Xiankuo Yu, Yifei Dai, Kequan Lin

Research (Wash D C)· October 2025

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Identification of chemical inhibitors targeting long noncoding RNA through gene signature-based high throughput screening.
Jun An, Huili Wang, Mingming Wei, Xiankuo Yu, Yile Liao, Kequan Lin

Int J Biol Macromol· March 2025

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Chromatin accessibility dynamics in colorectal cancer liver metastasis: Uncovering the liver tropism at single cell resolution.
Shasha Li, Ming Yang, Shuaishuai Teng, Kequan Lin, Yumei Wang

Pharmacol Res· September 2023

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IMPACT: A web server for exploring immunotherapeutic predictive and cancer prognostic biomarkers.
Yutao Liu, Yundi Zhang, Wenchuan Xie, Jing Zhao, Yiting Dong, Kequan Lin

Clin Transl Med· September 2023

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Long non-coding RNA DARS-AS1 promotes tumor progression by directly suppressing PACT-mediated cellular stress.
Liuqing Yang, Kequan Lin, Lin Zhu, Huili Wang, Shuaishuai Teng

Commun Biol· August 2022

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Genetic association and single-cell transcriptome analyses reveal distinct features connecting autoimmunity with cancers.
Shasha Li, Chenyang Lu, Yuan Zhang, Xiaolu Zhao, Kequan Lin

iScience· July 2022

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Oncogenic lncRNA LINC00973 promotes Warburg effect by enhancing LDHA enzyme activity.
Huili Wang, Kequan Lin, Lin Zhu, Shaojun Zhang, Le Li

Sci Bull (Beijing)· July 2021

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A large-scale transcriptional study reveals inhibition of COVID-19 related cytokine storm by traditional Chinese medicines.
Yifei Dai, Weijie Qiang, Yu Gui, Xue Tan, Tianli Pei, Kequan Lin

Sci Bull (Beijing)· May 2021

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An immune-related gene signature for predicting survival and immunotherapy efficacy in hepatocellular carcinoma.
Yifei Dai, Weijie Qiang, Kequan Lin, Yu Gui, Xun Lan

Cancer Immunol Immunother· April 2021

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Tumor immunological phenotype signature-based high-throughput screening for the discovery of combination immunotherapy compounds.
Haiyan Wang, Shasha Li, Qianyu Wang, Zhengshuo Jin, Wei Shao, Kequan Lin, Lin Zhu

Sci Adv· January 2021

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A comprehensive evaluation of connectivity methods for L1000 data.
Kequan Lin, Lu Li, Yifei Dai, Huili Wang, Shuaishuai Teng, Xilinqiqige Bao

Brief Bioinform· December 2020

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Guizhi Fuling Decoction inhibiting the PI3K and MAPK pathways in breast cancer cells revealed by HTS technology and systems pharmacology.
Yifei Dai, Weijie Qiang, Xiankuo Yu, Siwei Cai, Kequan Lin

Comput Struct Biotechnol J· May 2020

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Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer.
Shuaishuai Teng, Yang Eric Li, Ming Yang, Rui Qi, Yiming Huang, Kequan Lin

Cell Res· January 2020

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Chemical genomics reveals inhibition of breast cancer lung metastasis by Ponatinib via c-Jun.
Wei Shao, Shasha Li, Lu Li, Kequan Lin, Xinhong Liu

Protein Cell· March 2019

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