Publications by authors named "Kerstin B Kaufmann"

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Context and timing matters in acute myeloid leukemia: females are the superior hosts.
Kerstin B Kaufmann, Stephanie Z Xie

Haematologica· May 2025

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Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing.
Tomer Itkin, Sean Houghton, Ryan Schreiner, Yang Lin, Chaitanya R Badwe, Kerstin B Kaufmann

Nat Immunol· March 2025

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Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties.
Héléna Boutzen, Alex Murison, Alexa Oriecuia, Suraj Bansal, Christopher Arlidge, Kerstin B Kaufmann

Leukemia· October 2024

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Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle.
Carys S Johnson, Matthew Williams, Kendig Sham, Serena Belluschi, Wenjuan Ma, Kerstin B Kaufmann

Blood· August 2024

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Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Winnie L Kan, Urmi Dhagat, Kerstin B Kaufmann, Timothy R Hercus, Tracy L Nero

Cancer Discov· August 2023

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Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing.
Tomer Itkin, Sean Houghton, Ryan Schreiner, Yang Lin, Chaitanya R Badwe, Kerstin B Kaufmann

bioRxiv· March 2023

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A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.
Héléna Boutzen, Seyed Ali Madani Tonekaboni, Michelle Chan-Seng-Yue, Alex Murison, Naoya Takayama, Kerstin B Kaufmann

Leukemia· November 2022

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The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.
Geethu Emily Thomas, Grace Egan, Laura García-Prat, Aaron Botham, Veronique Voisin, Kerstin B Kaufmann

Nat Cell Biol· June 2022

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TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate.
Laura García-Prat, Kerstin B Kaufmann, Florin Schneiter, Veronique Voisin, Alex Murison

Cell Stem Cell· October 2021

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A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness.
Kerstin B Kaufmann, Andy G X Zeng, Etienne Coyaud, Laura Garcia-Prat, Efthymia Papalexi

Nat Immunol· June 2021

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The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.
Naoya Takayama, Alex Murison, Shin-Ichiro Takayanagi, Christopher Arlidge, Stanley Zhou, Kerstin B Kaufmann

Cell Stem Cell· March 2021

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Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation.
Stephanie Z Xie, Kerstin B Kaufmann, Weijia Wang, Michelle Chan-Seng-Yue, Olga I Gan

Blood Cancer Discov· January 2021

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Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal.
Stephanie Z Xie, Laura Garcia-Prat, Veronique Voisin, Robin Ferrari, Olga I Gan, Kerstin B Kaufmann

Cell Stem Cell· November 2019

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A stemness screen reveals as a promoter of human leukemia stem cell latency.
Kerstin B Kaufmann, Laura Garcia-Prat, Qiang Liu, Stanley W K Ng, Shin-Ichiro Takayanagi

Blood· May 2019

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Surface Functionalization of Orthopedic Titanium Implants with Bone Sialoprotein.
Andreas Baranowski, Anja Klein, Ulrike Ritz, Angelika Ackermann, Joris Anthonissen, Kerstin B Kaufmann

PLoS One· March 2017

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Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.
Jinghui Zhang, Kelly McCastlain, Hiroki Yoshihara, Beisi Xu, Yunchao Chang, Kerstin B Kaufmann

Nat Genet· December 2016

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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.
Eric R Lechman, Bernhard Gentner, Stanley W K Ng, Erwin M Schoof, Peter van Galen, Kerstin B Kaufmann

Cancer Cell· April 2016

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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.
Eric R Lechman, Bernhard Gentner, Stanley W K Ng, Erwin M Schoof, Peter van Galen, Kerstin B Kaufmann

Cancer Cell· February 2016

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Distinct routes of lineage development reshape the human blood hierarchy across ontogeny.
Faiyaz Notta, Sasan Zandi, Naoya Takayama, Stephanie Dobson, Olga I Gan, Kerstin B Kaufmann

Science· January 2016

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Gene therapy for chronic granulomatous disease: current status and future perspectives.
Kerstin B Kaufmann, Maria Chiriaco, Ulrich Siler, Andrea Finocchi, Janine Reichenbach

Curr Gene Ther· July 2015

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Generation of X-CGD cells for vector evaluation from healthy donor CD34(+) HSCs by shRNA-mediated knock down of gp91(phox).
Christian Brendel, Kerstin B Kaufmann, Anja Krattenmacher, Shweta Pahujani, Manuel Grez

Mol Ther Methods Clin Dev· May 2015

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CD105 is a surface marker for receptor-targeted gene transfer into human long-term repopulating hematopoietic stem cells.
Sarah-Katharina Kays, Kerstin B Kaufmann, Tobias Abel, Christian Brendel, Halvard Bonig

Stem Cells Dev· March 2015

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CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells.
Christian Brendel, Benjamin Goebel, Abriss Daniela, Martijn Brugman, Sabrina Kneissl, Kerstin B Kaufmann

Mol Ther· January 2015

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Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment.
Aya Ludin, Shiri Gur-Cohen, Karin Golan, Kerstin B Kaufmann, Tomer Itkin

Antioxid Redox Signal· October 2014

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Gene therapy on the move.
Kerstin B Kaufmann, Hildegard Büning, Anne Galy, Axel Schambach, Manuel Grez

EMBO Mol Med· November 2013

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