Publications by authors named "Kerstin N Timm"

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Impaired striatal glutathione-ascorbate metabolism induces transient dopamine increase and motor dysfunction.
Mohd Yaseen Malik, Fei Guo, Aman Asif-Malik, Vasileios Eftychidis, Nikolaos Barkas, Kerstin N Timm

Nat Metab· November 2024

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AICAR confers prophylactic cardioprotection in doxorubicin-induced heart failure in rats.
Anurag Choksey, Ryan D Carter, Benjamin D Thackray, Vicky Ball, Brett W C Kennedy, Kerstin N Timm

J Mol Cell Cardiol· June 2024

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Mechanisms of trastuzumab induced cardiotoxicity - is exercise a potential treatment?
Holden Eaton, Kerstin Nina Timm

Cardiooncology· April 2023

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Metabolic Effects of Doxorubicin on the Rat Liver Assessed With Hyperpolarized MRI and Metabolomics.
Kerstin N Timm, Vicky Ball, Jack J Miller, Dragana Savic, James A West

Front Physiol· January 2022

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Cancer Therapy-Induced Cardiotoxicity-A Metabolic Perspective on Pathogenesis, Diagnosis and Therapy.
Anurag Choksey, Kerstin N Timm

Int J Mol Sci· December 2021

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Rapid, -insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.
Jack J Miller, Ladislav Valkovič, Matthew Kerr, Kerstin N Timm, William D Watson

Magn Reson Med· June 2021

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Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart.
Dragana Savic, Vicky Ball, Lorenz Holzner, David Hauton, Kerstin N Timm

NMR Biomed· April 2021

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L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI.
Dragana Savic, Vicky Ball, M Kate Curtis, Maria da Luz Sousa Fialho, Kerstin N Timm

Metabolites· March 2021

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A 3D hybrid-shot spiral sequence for hyperpolarized imaging.
Andrew Tyler, Justin Y C Lau, Vicky Ball, Kerstin N Timm, Tony Zhou

Magn Reson Med· February 2021

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Probing hepatic metabolism of [2-C]dihydroxyacetone in vivo with H-decoupled hyperpolarized C-MR.
Irene Marco-Rius, Alan J Wright, De-En Hu, Dragana Savic, Jack J Miller, Kerstin N Timm

MAGMA· February 2021

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Nicotinic acid receptor agonists impair myocardial contractility by energy starvation.
William D Watson, Kerstin N Timm, Andrew J Lewis, Jack J J Miller, Yaso Emmanuel

FASEB J· November 2020

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Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.
Kerstin N Timm, Charith Perera, Vicky Ball, John A Henry, Jack J Miller

Commun Biol· November 2020

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Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol.
Matthew Kerr, Jack J Miller, Dharendra Thapa, Sophie Stiewe, Kerstin N Timm

JCI Insight· September 2020

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The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity.
Kerstin N Timm, Damian J Tyler

Cardiovasc Drugs Ther· April 2020

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Cardiac applications of hyperpolarised magnetic resonance.
Kerstin N Timm, Jack J Miller, John A Henry, Damian J Tyler

Prog Nucl Magn Reson Spectrosc· July 2019

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Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS.
Kerstin N Timm, Andrew Apps, Jack J Miller, Vicky Ball, Cher-Rin Chong

NMR Biomed· September 2018

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Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes.
Michael S Dodd, Maria da Luz Sousa Fialho, Claudia N Montes Aparicio, Matthew Kerr, Kerstin N Timm

JACC Basic Transl Sci· August 2018

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Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-13C]Dehydroascorbic Acid Reduction Using 13C Magnetic Resonance Spectroscopy.
Kerstin N Timm, De-En Hu, Michael Williams, Alan J Wright, Mikko I Kettunen

J Biol Chem· February 2017

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Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response.
Kerstin N Timm, Brett W C Kennedy, Kevin M Brindle

Clin Cancer Res· November 2016

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(13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.
Piotr Dzien, Sui-Seng Tee, Mikko I Kettunen, Scott K Lyons, Timothy J Larkin, Kerstin N Timm

Magn Reson Med· August 2016

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Hyperpolarized [U-(2) H, U-(13) C]Glucose reports on glycolytic and pentose phosphate pathway activity in EL4 tumors and glycolytic activity in yeast cells.
Kerstin N Timm, Johannes Hartl, Markus A Keller, De-En Hu, Mikko I Kettunen

Magn Reson Med· December 2015

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(13) C magnetic resonance spectroscopic imaging of hyperpolarized [1-(13) C, U-(2) H5 ] ethanol oxidation can be used to assess aldehyde dehydrogenase activity in vivo.
Piotr Dzien, Mikko I Kettunen, Irene Marco-Rius, Eva M Serrao, Tiago B Rodrigues, Kerstin N Timm

Magn Reson Med· May 2015

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Detection of transgene expression using hyperpolarized 13C urea and diffusion-weighted magnetic resonance spectroscopy.
P Stephen Patrick, Mikko I Kettunen, Sui-Seng Tee, Tiago B Rodrigues, Eva Serrao, Kerstin N Timm

Magn Reson Med· April 2015

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Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse.
Irene Marco-Rius, Michael C D Tayler, Mikko I Kettunen, Timothy J Larkin, Kerstin N Timm

NMR Biomed· December 2013

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