Publications by authors named "Kevan Jacobson"

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Metabolomics reveal distinct molecular pathways associated with future risk of Crohn's Disease.
Mingyue Xue, Sun-Ho Lee, Jingchen Shao, Haim Leibovitzh, Hien Q Huynh, Kevan Jacobson

Gut Microbes· December 2025

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Preclinical stages of Crohn's disease defined by faecal calprotectin in asymptomatic first-degree relatives: screening framework for prevention trials.
Dan Turner, Sarah Kenigsberg, Gili Focht, Williams Turpin, Oren Ledder, Kevan Jacobson

Gut· December 2025

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Author Correction: E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis.
Jay V Patankar, Tanja M Müller, Srinivas Kantham, Miguel Gonzalez Acera, Fabrizio Mascia, Kevan Jacobson

Nat Cell Biol· December 2025

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Serum C-X-C motif chemokine ligand 9, interleukin 8, and interleukin 22 as key biomarkers in pediatric inflammatory bowel disease.
Adi Eindor-Abarbanel, Kevin Tsai, Ash Sandhu, Bruce Vallance, Kevan Jacobson

World J Gastroenterol· December 2025

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Pyridostigmine as treatment for chronic gastrointestinal dysmotility in a child with Mowat-Wilson syndrome: A case report and literature review.
Grace J Lin, Shreya B Kishore, Sally Samaan, Lisa S Hackett, Kevan Jacobson

JPGN Rep· November 2025

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Using machine learning to predict clinical remission with exclusive enteral nutrition in pediatric Crohn disease.
Ricardo G Suarez Suarez, Daniel G McClement, Roberto Vega, Hien Q Huynh, Ayub Shaikh, Kevan Jacobson

J Pediatr Gastroenterol Nutr· November 2025

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Nociceptor neurons suppress alveolar macrophage-induced Siglec-F neutrophil-mediated inflammation to protect against pulmonary fibrosis.
Carlos H Hiroki, Mortaza F Hassanabad, Manon Defaye, Nicole Sarden, Alexandria Bartlett, Kevan Jacobson

Immunity· August 2025

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Fasting elicits gut microbiome signature changes that extend to type 1 diabetes patients.
Franziska A Graef, Bettina Berger, Lina S Bahr, Rainer Stange, Andreas Michalsen, Kevan Jacobson

Front Endocrinol (Lausanne)· August 2025

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Crosstalk with infant-derived Th17 cells, as well as exposure to IL-22 promotes maturation of intestinal epithelial cells in an enteroid model.
Zohreh Sharafian, Paula T Littlejohn, Christina Michalski, James A Sousa, Janelle Cheung, Kevan Jacobson

Front Immunol· May 2025

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Durability of Antibody Responses to SARS-CoV-2 Vaccination over 12 Months in Pediatric Inflammatory Bowel Disease.
Sally J Lawrence, Marina Viñeta Paramo, Frederic Reicherz, Jeffrey N Bone, Zahra Jama Hussein Shire, Kevan Jacobson

Vaccines (Basel)· May 2025

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Development of novel GI-centric prostaglandin E receptor type 4 (EP4) agonist prodrugs as treatment for ulcerative colitis and other intestinal inflammatory diseases.
Srinivas Kantham, Hongbing Yu, Christophe R Cantelli, Gang Chen, Caixia Ma, Kevan Jacobson

Bioorg Med Chem Lett· April 2025

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Neutrophil-to-Lymphocyte Ratio at Diagnosis Predicts Colonoscopic Activity in Pediatric Inflammatory Bowel Diseases.
Bishoi Aziz, Reza Belaghi, Hien Huynh, Kevan Jacobson, David R Mack

Clin Transl Gastroenterol· April 2025

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Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease.
Sun-Ho Lee, Maham Bushra, Lanhui Qiu, Anne M Griffiths, Williams Turpin, Kevan Jacobson

Gastroenterology· February 2025

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Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn's Disease.
Pablo A Olivera, Helena Martinez-Lozano, Haim Leibovitzh, Mingyue Xue, Anna Neustaeter, Kevan Jacobson

Gastroenterology· January 2025

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Health Services Utilization and Specialist Care in Pediatric Inflammatory Bowel Disease: A Multiprovince Population-Based Cohort Study.
M Ellen Kuenzig, Alain Bitton, Matthew W Carroll, Anthony R Otley, Harminder Singh, Kevan Jacobson

Inflamm Bowel Dis· December 2024

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Landscape of TPMT and NUDT15 Pharmacogenetic Variation in a Cohort of Canadian Pediatric Inflammatory Bowel Disease Patients.
April M Kennedy, Anne M Griffiths, Aleixo M Muise, Thomas D Walters, Amanda Ricciuto, Kevan Jacobson

Inflamm Bowel Dis· December 2024

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Bolstering connectedness through peer support: Randomized-controlled trial of a web-based peer support program for adolescents with inflammatory bowel disease.
Meghan K Ford, Armanda Iuliano, Thomas D Walters, Anthony R Otley, David R Mack, Kevan Jacobson

Health Care Transit· November 2024

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Forecasting the Incidence and Prevalence of Inflammatory Bowel Disease: A Canadian Nationwide Analysis.
Stephanie Coward, Eric I Benchimol, Charles N Bernstein, Antonio Avina-Zubieta, Alain Bitton, Kevan Jacobson

Am J Gastroenterol· August 2024

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The role of upper gastrointestinal endoscopy in the diagnosis of pediatric inflammatory bowel disease.
Becky Biqi Chen, Zachary Hamilton, Mohammed Hasosah, Peter Zetler, Oana Popescu, Kevan Jacobson

Am J Clin Pathol· June 2024

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Pre-Diagnosis Diet Predicts Response to Exclusive Enteral Nutrition and Correlates with Microbiome in Pediatric Crohn Disease.
Stephanie Dijk, Megan Jarman, Zhengxiao Zhang, Morgan Lawley, Muzammil Ahmad, Kevan Jacobson

Nutrients· April 2024

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Adalimumab vs Infliximab in Luminal Pediatric Crohn's Disease: Comparable Outcomes in a Prospective Multicenter Cohort Study.
Jennifer C deBruyn, Hien Q Huynh, Anne M Griffiths, Kevan Jacobson, David Mack

Am J Gastroenterol· March 2024

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Outcomes Following Acute Severe Colitis at Initial Presentation: A Multi-centre, Prospective, Paediatric Cohort Study.
Jasbir Dhaliwal, Dominique Tertigas, Nicholas Carman, Sally Lawrence, Jennifer C Debruyn, Kevan Jacobson

J Crohns Colitis· February 2024

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Insights Into Inflammatory Bowel Disease and Effects of Dietary Fatty Acid Intake With a Focus on Polyunsaturated Fatty Acids Using Preclinical Models.
Matthew Smyth, Genelle Lunken, Kevan Jacobson

J Can Assoc Gastroenterol· February 2024

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Variation in the Care of Children with Inflammatory Bowel Disease Within and Across Canadian Provinces: A Multi-Province Population-Based Cohort Study.
M Ellen Kuenzig, Therese A Stukel, Matthew W Carroll, Gilaad G Kaplan, Anthony R Otley, Kevan Jacobson

Clin Epidemiol· February 2024

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User testing to modify the MyHealthyGut digital health application for inflammatory bowel disease.
Madeline Erlich, Sarah Lindblad, Natasha Haskey, Darlene Higbee Clarkin, Taojie Dong, Kevan Jacobson

Digit Health· September 2023

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