Publications by authors named "Kevin A Cassady"

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CAR T-cell and oncolytic virus dynamics and determinants of combination therapy success for glioblastoma.
Martina Conte, Agata Xella, Ryan T Woodall, Kevin A Cassady, Sergio Branciamore

Math Biosci· November 2025

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Direct oHSV Infection Induces DC Maturation and a Tumor Therapeutic Response.
Doyeon Kim, Michael Kelly, Jack Hedberg, Alexia K Martin, Ilse Hernandez-Aguirre, Kevin A Cassady

Viruses· August 2025

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Oncolytic HSV-IL27 expression improves CD8 T cell function and therapeutic activity in syngeneic glioma models.
Alexia K Martin, Jack Hedberg, Ilse Hernandez-Aguirre, Uksha Saini, Doyeon Kim, Kevin A Cassady

J Immunother Cancer· July 2025

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Oncolytic HSV-IL27 expression improves CD8 T cell function and therapeutic activity in syngeneic glioma models.
Alexia Martin, Jack Hedberg, Ilse Aguirre-Hernandez, Uksha Saini, Doyeon Kim, Kevin A Cassady

bioRxiv· May 2025

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Ruxolitinib and oHSV combination therapy increases CD4 T cell activity and germinal center B cell populations in murine sarcoma.
Ravi Dhital, Yeaseul Kim, Doyeon Kim, Ilse Hernandez-Aguirre, Jack Hedberg, Kevin A Cassady

Mol Ther Oncol· March 2025

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Combinatorial immunotherapy with anti-ROR1 CAR NK cells and an IL-21 secreting oncolytic virus against neuroblastoma.
Yaya Chu, Meijuan Tian, Uksha Saini, Jessica Ayala-Cuesta, Kayleigh Klose, Kevin A Cassady

Mol Ther Oncol· March 2025

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CAR T-cell and oncolytic virus dynamics and determinants of combination therapy success for glioblastoma.
Martina Conte, Agata Xella, Ryan T Woodall, Kevin A Cassady, Sergio Branciamore

bioRxiv· January 2025

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Combinatorial macrophage induced innate immunotherapy against Ewing sarcoma: Turning "Two Keys" simultaneously.
Wen Luo, Hai Hoang, Katherine E Miller, Hongwen Zhu, Serena Xu, Kevin A Cassady

J Exp Clin Cancer Res· July 2024

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Corrigendum: Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors.
Siddhi N Paudel, Brian J Hutzen, Katherine E Miller, Elizabeth A R Garfinkle, Chun-Yu Chen, Kevin A Cassady

Front Immunol· July 2024

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Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors.
Siddhi N Paudel, Brian J Hutzen, Katherine E Miller, Elizabeth A R Garfinkle, Chun-Yu Chen, Kevin A Cassady

Front Immunol· July 2024

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Enhanced IL-12 transgene expression improves oncolytic viroimmunotherapy.
Yeaseul Kim, Uksha Saini, Doyeon Kim, Ilse Hernandez-Aguirre, Jack Hedberg, Kevin A Cassady

Front Immunol· June 2024

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Oncolytic virus-driven immune remodeling revealed in mouse medulloblastomas at single cell resolution.
Jack Hedberg, Adam Studebaker, Luke Smith, Chun-Yu Chen, Jesse J Westfall, Kevin A Cassady

Mol Ther Oncolytics· September 2023

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Pediatric versus adult high grade glioma: Immunotherapeutic and genomic considerations.
Payal Aggarwal, Wen Luo, Katherine C Pehlivan, Hai Hoang, Prajwal Rajappa, Kevin A Cassady

Front Immunol· December 2022

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Immune Activity and Response Differences of Oncolytic Viral Therapy in Recurrent Glioblastoma: Gene Expression Analyses of a Phase IB Study.
Katherine E Miller, Kevin A Cassady, Justin C Roth, Jennifer Clements, Kathleen M Schieffer

Clin Cancer Res· February 2022

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Eliciting an immune-mediated antitumor response through oncolytic herpes simplex virus-based shared antigen expression in tumors resistant to viroimmunotherapy.
Mohammed G Ghonime, Uksha Saini, Michael C Kelly, Justin C Roth, Pin-Yi Wang, Kevin A Cassady

J Immunother Cancer· October 2021

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Inosine is an alternative carbon source for CD8-T-cell function under glucose restriction.
Tingting Wang, J N Rashida Gnanaprakasam, Xuyong Chen, Siwen Kang, Xuequn Xu, Kevin A Cassady

Nat Metab· July 2020

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Immunotherapeutic Challenges for Pediatric Cancers.
Brian Hutzen, Mohammed Ghonime, Joel Lee, Elaine R Mardis, Ruoning Wang, Kevin A Cassady

Mol Ther Oncolytics· December 2019

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STING Restricts oHSV Replication and Spread in Resistant MPNSTs but Is Dispensable for Basal IFN-Stimulated Gene Upregulation.
Joel M Lee, Mohammed G Ghonime, Kevin A Cassady

Mol Ther Oncolytics· December 2019

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Immunotherapies for pediatric cancer: current landscape and future perspectives.
Brian Hutzen, Siddhi Nath Paudel, Meisam Naeimi Kararoudi, Kevin A Cassady, Dean A Lee

Cancer Metastasis Rev· December 2019

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Adjuvant haploidentical virus-specific T lymphocytes for treatment of disseminated adenovirus infection in a premature infant.
Jeffery J Auletta, Pablo J Sánchez, Erin K Meyer, Lynn C O'Donnell, Kevin A Cassady

J Allergy Clin Immunol· August 2019

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The Antiviral Apparatus: STING and Oncolytic Virus Restriction.
Joel Lee, Mohammed G Ghonime, Ruoning Wang, Kevin A Cassady

Mol Ther Oncolytics· June 2019

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Oncolytic Virus-Based Cytokine Expression to Improve Immune Activity in Brain and Solid Tumors.
Taylor M Pearl, James M Markert, Kevin A Cassady, Mohammed G Ghonime

Mol Ther Oncolytics· June 2019

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Combination Therapy Using Ruxolitinib and Oncolytic HSV Renders Resistant MPNSTs Susceptible to Virotherapy.
Mohammed G Ghonime, Kevin A Cassady

Cancer Immunol Res· December 2018

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Myelolytic Treatments Enhance Oncolytic Herpes Virotherapy in Models of Ewing Sarcoma by Modulating the Immune Microenvironment.
Nicholas L Denton, Chun-Yu Chen, Brian Hutzen, Mark A Currier, Thomas Scott, Kevin A Cassady

Mol Ther Oncolytics· December 2018

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Please stand by: how oncolytic viruses impact bystander cells.
Leslee Sprague, Lynne Braidwood, Joe Conner, Kevin A Cassady, Fabian Benencia

Future Virol· September 2018

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