Publications by authors named "Kevin Blake"

Claim this Profile
S
State of omics-based microbial diagnostics of CRC.
Jerome Prusa, Mark G Gorelik, Kevin S Blake, Gautam Dantas

Gut Microbes· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A survey of regulatory recommendations for waivers of bioequivalence studies of generic products for certain dosage forms by participating regulators and organisations of the International Pharmaceutical Regulators Programme. Part 2.
Alfredo García-Arieta, Andrew Tam, Florencia Tiseyra, Eduardo Agostinho Freitas Fernandes, Kelen Carine Costa Soares, Kevin Blake

J Pharm Pharm Sci· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reply to: "Current Use of PBPK Modeling in New Medicinal Product Approvals at EMA: A Clinical Appraisal of Voclosporin in Lupus Nephritis".
Polly Paul, Pieter J Colin, Flora Musuamba Tshinanu, Carolien Versantvoort, Efthymios Manolis, Kevin Blake

Clin Pharmacol Ther· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Current Use of Physiologically Based Pharmacokinetic modeling in New Medicinal Product Approvals at EMA.
Polly Paul, Pieter J Colin, Flora Musuamba Tshinanu, Carolien Versantvoort, Efthymios Manolis, Kevin Blake

Clin Pharmacol Ther· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
C10-Benzoate Esters of Anhydrotetracycline Inhibit Tetracycline Destructases and Recover Tetracycline Antibacterial Activity.
Emily E Williford, Yao-Peng Xue, Wai Kwan Tang, Ruihao Li, Katherine V Jones, Kevin S Blake

ACS Infect Dis· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation.
Kevin S Blake, Yao-Peng Xue, Vincent J Gillespie, Skye R S Fishbein, Niraj H Tolia

Nat Commun· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Missing microbiomes: global underrepresentation restricts who research will benefit.
Kevin S Blake

J Clin Invest· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Two-Way Proposal for the Determination of Bioequivalence for Narrow Therapeutic Index Drugs in the European Union.
Paulo Paixao, Alfredo Garcia Arieta, Nuno Silva, Zvonimir Petric, Milton Bonelli, Kevin Blake

Pharmaceutics· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.
Kevin S Blake, Hirdesh Kumar, Anisha Loganathan, Emily E Williford, Luke Diorio-Toth

Commun Biol· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Gut microbiome and antibiotic resistance effects during travelers' diarrhea treatment and prevention.
Kevin S Blake, Drew J Schwartz, Srinand Paruthiyil, Bin Wang, Jie Ning

mBio· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Using mechanistic models to support development of complex generic drug products: European Medicines Agency perspective.
Efthymios Manolis, Alfredo García-Arieta, Anders Lindahl, Evangelos Kotzagiorgis, Jobst Limberg, Kevin Blake

CPT Pharmacometrics Syst Pharmacol· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Publisher Correction: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas

Commun Biol· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas

Commun Biol· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling.
Emily E Williford, Caitlin M DeAngelo, Kevin S Blake, Hirdesh Kumar, Kendrick K Lam

J Med Chem· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metagenomic Insight into Microbiome and Antibiotic Resistance Genes of High Clinical Concern in Urban and Rural Hospital Wastewater of Northern India Origin: a Major Reservoir of Antimicrobial Resistance.
Absar Talat, Kevin S Blake, Gautam Dantas, Asad U Khan

Microbiol Spectr· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Impact of international travel and diarrhea on gut microbiome and resistome dynamics.
Manish Boolchandani, Kevin S Blake, Drake H Tilley, Miguel M Cabada, Drew J Schwartz

Nat Commun· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of a Proposed Approach for the Determination of the Bioequivalence Acceptance Range for Narrow Therapeutic Index Drugs in the European Union.
Paulo Paixão, Nuno Silva, Rita Bento Guerreiro, Kevin Blake, Milton Bonelli

Pharmaceutics· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Proposed Approach for the Determination of the Bioequivalence Acceptance Range for Narrow Therapeutic Index Drugs in the European Union.
Paulo Paixão, Rita Bento Guerreiro, Nuno Silva, Kevin Blake, Milton Bonelli

Clin Pharmacol Ther· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Approaches for characterizing and tracking hospital-associated multidrug-resistant bacteria.
Kevin S Blake, JooHee Choi, Gautam Dantas

Cell Mol Life Sci· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Overview of the European Medicines Agency's Experience With Biowaivers in Centralized Applications.
Ines Lenić, Kevin Blake, Alfredo Garcia-Arieta, Henrike Potthast, Jan Welink

Clin Transl Sci· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A European multicentre drug utilisation study of the impact of regulatory measures on prescribing of codeine for pain in children.
Karin Hedenmalm, Kevin Blake, Katherine Donegan, Miguel-Angel Macia, Miguel Gil

Pharmacoepidemiol Drug Saf· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Commentary on the EMA Reflection Paper on the use of extrapolation in the development of medicines for paediatrics.
Cécile Ollivier, Andrew Thomson, Efthymios Manolis, Kevin Blake, Kristin E Karlsson

Br J Clin Pharmacol· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Response to: "The Role of Quantitative Systems Pharmacology in the Design of First-in-Human Trials".
Kevin Blake, Milton Bonelli, Stefano Ponzano, Harald Enzmann,

Clin Pharmacol Ther· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Overview of the European Medicines Agency's Development of Product-Specific Bioequivalence Guidelines.
Jane O' Sullivan, Kevin Blake, Michael Berntgen, Tomas Salmonson, Jan Welink

Clin Pharmacol Ther· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Promoting Safe Early Clinical Research of Novel Drug Candidates: A European Union Regulatory Perspective.
Stefano Ponzano, Kevin Blake, Milton Bonelli, Harald Enzmann,

Clin Pharmacol Ther· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis