Publications by authors named "Kevin Coote"

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Author Correction: A streamlined base editor engineering strategy to reduce bystander editing.
Izabella Valdez, Ian O'Connor, Divesh Patel, Katherine Gierer, Jan Harrington, Kevin Coote

Nat Commun· November 2025

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A streamlined base editor engineering strategy to reduce bystander editing.
Izabella Valdez, Ian O'Connor, Divesh Patel, Katherine Gierer, Jan Harrington, Kevin Coote

Nat Commun· August 2025

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ACE-tRNAs are a platform technology for suppressing nonsense mutations that cause cystic fibrosis.
Wooree Ko, Joseph J Porter, Sacha Spelier, Emily G Sorensen, Priyanka Bhatt, Kevin Coote

Nucleic Acids Res· July 2025

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A multimodal iPSC platform for cystic fibrosis drug testing.
Andrew Berical, Rhianna E Lee, Junjie Lu, Mary Lou Beermann, Jake A Le Suer, Kevin Coote

Nat Commun· July 2022

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Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope.
Tingting Jiang, Jordana M Henderson, Kevin Coote, Yi Cheng, Hillary C Valley

Nat Commun· April 2020

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Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 2: α-Branched quaternary amines.
Thomas Hunt, Hazel C Atherton-Watson, Stephen P Collingwood, Kevin J Coote, Sarah Czarnecki

Bioorg Med Chem Lett· April 2012

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Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 1: quaternary amines.
Thomas Hunt, Hazel C Atherton-Watson, Jake Axford, Stephen P Collingwood, Kevin J Coote

Bioorg Med Chem Lett· January 2012

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In vivo assessments of mucus dynamics in the rat lung using a Gd-Cy5.5-bilabeled contrast agent for magnetic resonance and optical imaging.
François-Xavier Blé, Philipp Schmidt, Catherine Cannet, Rainer Kneuer, Harry Karmouty-Quintana, Kevin Coote

Magn Reson Med· November 2009

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Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect.
Christopher S Stevenson, Kevin Coote, Ruth Webster, Helinor Johnston, Hazel C Atherton

Am J Physiol Lung Cell Mol Physiol· March 2005

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Mucociliary clearance is enhanced in rat models of cigarette smoke and lipopolysaccharide-induced lung disease.
Kevin Coote, Andy Nicholls, Hazel C Atherton, Rosemary Sugar, Henry Danahay

Exp Lung Res· August 2004

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