Publications by authors named "Kevin Couper"

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The tumour immune microenvironment is enriched but suppressed in vestibular schwannoma compared to meningioma: therapeutic implications for NF2-related schwannomatosis.
Grace E Gregory, Michael J Haley, Adam Paul Jones, Leo A H Zeef, D Gareth Evans, Kevin N Couper

Acta Neuropathol Commun· December 2025

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Skull-meninges-brain connectivity and extra-axial brain tumours.
Abdurrahman I Islim, Alexandros Vyziotis, Omar N Pathmanaban, David J Coope, Andrew T King, Kevin N Couper

Brain Commun· August 2025

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Spatial gene regulatory networks driving cell state transitions during human liver disease.
Nigel L Hammond, Syed Murtuza Baker, Sokratia Georgaka, Ali Al-Anbaki, Elliot Jokl, Kevin N Couper

EMBO Mol Med· June 2025

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SOX9 plays an essential role in myofibroblast driven hepatic granuloma integrity and parenchymal repair during schistosomiasis-induced liver damage.
Kim Su, Elliot Jokl, Alice Costain, Kara Simpson, Antonn Cheeseman, Kevin N Couper

PLoS Pathog· June 2025

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Spatial mapping of immune cell environments in NF2-related schwannomatosis vestibular schwannoma.
Adam P Jones, Michael J Haley, Miriam H Meadows, Grace E Gregory, Cathal J Hannan, Kevin N Couper

Nat Commun· March 2025

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Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population.
James Nyirenda, Olympia M Hardy, João Da Silva Filho, Vanessa Herder, Charalampos Attipa, Kevin Couper

Nat Med· December 2024

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Synergistic blockade of TIGIT and PD-L1 increases type-1 inflammation and improves parasite control during murine blood-stage non-lethal infection.
Rebecca S Dookie, Ana Villegas-Mendez, Antonn Cheeseman, Adam P Jones, Ruben Barroso, Kevin N Couper

Infect Immun· November 2024

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Alternatively activated macrophages are associated with faster growth rate in vestibular schwannoma.
Grace E Gregory, Michael J Haley, Adam P Jones, Cathal J Hannan, D Gareth Evans, Kevin N Couper

Brain Commun· November 2024

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Ouroboros: cross-linking protein expression perturbations and cancer histology imaging with generative-predictive modeling.
Srijay Deshpande, Sokratia Georgaka, Michael Haley, Robert Sellers, James Minshull, Kevin Couper

Bioinformatics· September 2024

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A spatially resolved single-cell lung atlas integrated with clinical and blood signatures distinguishes COVID-19 disease trajectories.
João Da Silva Filho, Vanessa Herder, Matthew P Gibbins, Monique Freire Dos Reis, Gisely Cardoso Melo, Kevin N Couper

Sci Transl Med· September 2024

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Lymphatic network drainage resolves cerebral edema and facilitates recovery from experimental cerebral malaria.
Michael J Haley, Ruben Barroso, Dhifaf A Jasim, Megan Haigh, Jack Green, Kevin N Couper

Cell Rep· May 2024

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Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival.
Michael J Haley, Leoma Bere, James Minshull, Sokratia Georgaka, Natalia Garcia-Martin, Kevin N Couper

Sci Adv· May 2024

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Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture.
Basim Othman, Leo Zeef, Tadge Szestak, Zineb Rchiad, Janet Storm, Kevin Couper

PLoS One· December 2023

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Squaramides enhance NLRP3 inflammasome activation by lowering intracellular potassium.
Paula I Seoane, James A Beswick, Andrew G Leach, Tessa Swanton, Lucy V Morris, Kevin Couper

Cell Death Discov· December 2023

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Evaluation of 4-Aminoquinoline Hydrazone Analogues as Potential Leads for Drug-Resistant Malaria.
Rachael N Magwaza, Muna Abubaker, Buthaina Hussain, Michael Haley, Kevin Couper

Molecules· September 2023

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The comparable tumour microenvironment in sporadic and -related schwannomatosis vestibular schwannoma.
Grace E Gregory, Adam Paul Jones, Michael J Haley, Christopher Hoyle, Leo A H Zeef, Kevin N Couper

Brain Commun· July 2023

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Plasmodium falciparum-infected erythrocyte co-culture with the monocyte cell line THP-1 does not trigger production of soluble factors reducing brain microvascular barrier function.
Janet Storm, Grazia Camarda, Michael J Haley, David Brough, Kevin N Couper

PLoS One· May 2023

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The clinical, genetic, and immune landscape of meningioma in patients with NF2-schwannomatosis.
Grace E Gregory, Abdurrahman I Islim, Cathal John Hannan, Adam P Jones, Charlotte Hammerbeck-Ward, Kevin Couper

Neurooncol Adv· May 2023

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The NLRP3 inflammasome as a target for sensorineural hearing loss.
Grace E Gregory, Kevin J Munro, Kevin N Couper, Omar N Pathmanaban, David Brough

Clin Immunol· April 2023

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Increased Circulating Chemokines and Macrophage Recruitment in Growing Vestibular Schwannomas.
Cathal John Hannan, Daniel Lewis, Claire O'Leary, Mueez Waqar, David Brough, Kevin N Couper

Neurosurgery· March 2023

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Treatment with specific and pan-plasma membrane calcium ATPase (PMCA) inhibitors reduces malaria parasite growth in vitro and in vivo.
Puji B S Asih, Josephine E Siregar, Farahana K Dewayanti, Normalita E Pravitasari, Ismail E Rozi, Kevin N Couper

Malar J· June 2022

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Memory CD8 T cells exhibit tissue imprinting and non-stable exposure-dependent reactivation characteristics following blood-stage Plasmodium berghei ANKA infections.
Tovah N Shaw, Michael J Haley, Rebecca S Dookie, Jenna J Godfrey, Antonn J Cheeseman, Kevin N Couper

Immunology· December 2021

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The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria.
Ana Villegas-Mendez, Nicholas Stafford, Michael J Haley, Normalita Eka Pravitasari, Florence Baudoin, Kevin N Couper

Malar J· July 2021

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The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function.
Faisal Minshawi, Sebastian Lanvermann, Edward McKenzie, Rebecca Jeffery, Kevin Couper

Front Immunol· April 2021

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The impact of COVID-19 pandemic on malaria elimination.
Ayat Zawawi, Maimonah Alghanmi, Isra Alsaady, Hattan Gattan, Haytham Zakai, Kevin Couper

Parasite Epidemiol Control· November 2020

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