Publications by authors named "Kevin D Cook"

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Utility of Cellular Measurements of Non-Specific Endocytosis to Assess the Target-Independent Clearance of Monoclonal Antibodies.
Mark A Bryniarski, Md Tariqul Haque Tuhin, Carolyn D Shomin, Fatemeh Nasrollahi, Eunkyung Clare Ko, Kevin D Cook

J Pharm Sci· October 2024

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Cellular Neonatal Fc Receptor Recycling Efficiencies can Differentiate Target-Independent Clearance Mechanisms of Monoclonal Antibodies.
Mark A Bryniarski, Md Tariqul Haque Tuhin, Timothy M Acker, Devin L Wakefield, Panijaya Gemy Sethaputra, Kevin D Cook

J Pharm Sci· September 2024

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Rapid depletion of "catch-and-release" anti-ASGR1 antibody in vivo.
Siva Charan Devanaboyina, Peng Li, Edward L LaGory, Carrie Poon-Andersen, Kevin D Cook

MAbs· July 2024

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Corrigendum: Translatability of findings from cynomolgus monkey to human suggests a mechanistic role for IL-21 in promoting immunogenicity to an anti-PD-1/IL-21 mutein fusion protein.
Mark A Kroenke, Marta Starcevic Manning, Christina L Zuch de Zafra, Xinwen Zhang, Kevin D Cook

Front Immunol· June 2024

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Correlation of In Vitro Kinetic Stability to Preclinical In Vivo Pharmacokinetics for a Panel of Anti-PD-1 Monoclonal Antibody Interleukin 21 Mutein Immunocytokines.
Kevin D Cook, Thuy Tran, Veena A Thomas, Siva Charan Devanaboyina, Dan A Rock

Drug Metab Dispos· February 2024

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Translatability of findings from cynomolgus monkey to human suggests a mechanistic role for IL-21 in promoting immunogenicity to an anti-PD-1/IL-21 mutein fusion protein.
Mark A Kroenke, Marta Starcevic Manning, Christina L Zuch de Zafra, Xinwen Zhang, Kevin D Cook

Front Immunol· February 2024

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Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies.
Marissa Mock, Alex W Jacobitz, Christopher James Langmead, Athena Sudom, Daniel Yoo, Kevin D Cook

MAbs· November 2023

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Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice.
Shufang Liu, Sara C Humphreys, Kevin D Cook, Kip P Conner, Ana R Correia

MAbs· November 2023

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Development of an immunoassay for aglycosylated murine IgG1 in mouse serum via generation of a specific tool antibody.
Carrie Poon-Andersen, Hamsini Dhoolypala, Diana Wong, Marcus Soto, Hossein Salimi-Moosavi, Kevin D Cook

Bioanalysis· May 2022

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POE Immunoassay: Plate-based oligonucleotide electro-chemiluminescent immunoassay for the quantification of nucleic acids in biological matrices.
Mai B Thayer, Sara C Humphreys, Kyu S Chung, Julie M Lade, Kevin D Cook

Sci Rep· June 2020

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A quantitative method for detection of circulating fms related tyrosine kinase 3 (FLT-3) in acute myeloid leukemia (AML) patients.
Kevin D Cook, Elizabeth C Finger, Cedric Dos Santos, Dan A Rock

J Immunol Methods· July 2019

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Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection.
Ichiro Misumi, Kevin D Cook, Joseph E Mitchell, Makayla M Lund, Sarah C Vick

Cell Rep· April 2019

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The Innate Immune Sensor NLRC3 Acts as a Rheostat that Fine-Tunes T Cell Responses in Infection and Autoimmunity.
Toru Uchimura, Yoshitaka Oyama, Meng Deng, Haitao Guo, Justin E Wilson, Kevin D Cook

Immunity· December 2018

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LAG-3 Confers a Competitive Disadvantage upon Antiviral CD8+ T Cell Responses.
Kevin D Cook, Jason K Whitmire

J Immunol· July 2016

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The Mouse Universal Genotyping Array: From Substrains to Subspecies.
Andrew P Morgan, Chen-Ping Fu, Chia-Yu Kao, Catherine E Welsh, John P Didion, Kevin D Cook

G3 (Bethesda)· December 2015

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Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium.
Vivien I Maltez, Alan L Tubbs, Kevin D Cook, Youssef Aachoui, E Liana Falcone

Immunity· November 2015

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T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX.
Kevin D Cook, Karl B Shpargel, Joshua Starmer, Fatima Whitfield-Larry, Bridget Conley

Immunity· October 2015

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NK cells inhibit humoral immunity by reducing the abundance of CD4+ T follicular helper cells during a chronic virus infection.
Kevin D Cook, Hannah C Kline, Jason K Whitmire

J Leukoc Biol· August 2015

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NK cells and their ability to modulate T cells during virus infections.
Kevin D Cook, Stephen N Waggoner, Jason K Whitmire

Crit Rev Immunol· July 2015

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The depletion of NK cells prevents T cell exhaustion to efficiently control disseminating virus infection.
Kevin D Cook, Jason K Whitmire

J Immunol· January 2013

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TCR-dependent translational control of GATA-3 enhances Th2 differentiation.
Kevin D Cook, Jim Miller

J Immunol· September 2010

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