Publications by authors named "Kevin D Kreutter"

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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
Mark S Tichenor, John J M Wiener, Navin L Rao, Genesis M Bacani, Jianmei Wei, Kevin D Kreutter

J Med Chem· November 2022

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Structural basis for isoform-specific inhibition of human CTPS1.
Eric M Lynch, Michael A DiMattia, Steven Albanese, Gydo C P van Zundert, Jesse M Hansen, Kevin D Kreutter

Proc Natl Acad Sci U S A· October 2021

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Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity.
Mark S Tichenor, John J M Wiener, Navin L Rao, Charlotte Pooley Deckhut, J Kent Barbay, Kevin D Kreutter

ACS Med Chem Lett· May 2021

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Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease.
Kristi A Leonard, Lisa A Madge, Paul J Krawczuk, Aihua Wang, Kevin D Kreutter

J Med Chem· March 2020

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6-Substituted quinolines as RORγt inverse agonists.
J Kent Barbay, Maxwell D Cummings, Marta Abad, Glenda Castro, Kevin D Kreutter

Bioorg Med Chem Lett· December 2017

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Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt.
David A Kummer, Maxwell D Cummings, Marta Abad, Joseph Barbay, Glenda Castro, Kevin D Kreutter

Bioorg Med Chem Lett· May 2017

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Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif.
Kevin D Kreutter, Tianbao Lu, Lily Lee, Edward C Giardino, Sharmila Patel

Bioorg Med Chem Lett· May 2008

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2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors.
Lily Lee, Kevin D Kreutter, Wenxi Pan, Carl Crysler, John Spurlino

Bioorg Med Chem Lett· November 2007

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