Publications by authors named "Kevin D Raney"

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Template switching by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir.
Asif Rakib, Arnab Das, Subhas C Bera, Pim P B America, Misha Klein, Kevin D Raney

bioRxiv· October 2025

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RNA virus polymerase-helicase coupling enables rapid elongation through duplex RNA.
Pim P B America, Subhas C Bera, Arnab Das, Thomas K Anderson, John C Marecki, Kevin D Raney

bioRxiv· June 2025

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A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent.
Misha Klein, Arnab Das, Subhas C Bera, Thomas K Anderson, Dana Kocincova, Kevin D Raney

Nucleic Acids Res· May 2025

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Biomolecular condensates control and are defined by RNA-RNA interactions that arise in viral replication.
Dilimulati Aierken, Vita Zhang, Rachel Sealfon, John C Marecki, Kevin D Raney

Res Sq· May 2025

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Autophosphorylation of the Tousled-like kinases TLK1 and TLK2 regulates recruitment to damaged chromatin via PCNA interaction.
Kirk L West, Tram T N Nguyen, Kyle A Tengler, Natasha Kreiling, Kevin D Raney

Nucleic Acids Res· February 2025

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A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent.
Misha Klein, Arnab Das, Subhas C Bera, Thomas K Anderson, Dana Kocincova, Kevin D Raney

bioRxiv· January 2025

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Biomolecular condensates control and are defined by RNA-RNA interactions that arise in viral replication.
Dilimulati Aierken, Vita Zhang, Rachel Sealfon, John C Marecki, Kevin D Raney

bioRxiv· December 2024

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Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge.
Zebin Hong, Alicia K Byrd, Jun Gao, Poulomi Das, Vanessa Qianmin Tan, Kevin D Raney

Nat Commun· July 2024

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Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth.
Jun Gao, David R Proffitt, John C Marecki, Reine U Protacio, Wayne P Wahls, Kevin D Raney

Nucleic Acids Res· June 2024

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Autophosphorylation of the Tousled-like kinases TLK1 and TLK2 regulates recruitment to damaged chromatin via PCNA interaction.
Kirk L West, Natasha Kreiling, Kevin D Raney, Gargi Ghosal, Justin W Leung

bioRxiv· April 2024

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Pif1 Helicase Mediates Remodeling of Protein-Nucleic Acid Complexes by Promoting Dissociation of Sub1 from G-Quadruplex DNA and Cdc13 from G-Rich Single-Stranded DNA.
Shubeena Chib, Wezley C Griffin, Jun Gao, David R Proffitt, Alicia K Byrd, Kevin D Raney

Biochemistry· December 2023

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Hepatitis C virus nonstructural protein NS3 unfolds viral G-quadruplex RNA structures.
Binyam Belachew, Jun Gao, Alicia K Byrd, Kevin D Raney

J Biol Chem· November 2022

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Alignment of helicases on single-stranded DNA increases activity.
Deniz Ozaslan, Alicia K Byrd, Binyam Belachew, Kevin D Raney

Methods Enzymol· August 2022

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Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways.
Magdalena Delgado, Randall R Rainwater, Billie Heflin, Alicja Urbaniak, Kaitlynn Butler, Kevin D Raney

J Biol Chem· June 2022

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A structural feature of Dda helicase which enhances displacement of streptavidin and trp repressor from DNA.
Alicia K Byrd, Emory G Malone, Lindsey Hazeslip, Maroof Khan Zafar, David K Harrison, Kevin D Raney

Protein Sci· February 2022

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RNA helicases required for viral propagation in humans.
John C Marecki, Binyam Belachew, Jun Gao, Kevin D Raney

Enzymes· December 2021

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G-quadruplex DNA inhibits unwinding activity but promotes liquid-liquid phase separation by the DEAD-box helicase Ded1p.
Jun Gao, Zhaofeng Gao, Andrea A Putnam, Alicia K Byrd, Sarah L Venus, Kevin D Raney

Chem Commun (Camb)· July 2021

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Identifying RNA Helicase Inhibitors Using Duplex Unwinding Assays.
John C Marecki, Alicia K Byrd, Kevin D Raney

Methods Mol Biol· March 2021

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G-Quadruplex loops regulate PARP-1 enzymatic activation.
Andrea D Edwards, John C Marecki, Alicia K Byrd, Jun Gao, Kevin D Raney

Nucleic Acids Res· January 2021

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Genome-wide Cas9 binding specificity in .
Zachary J Waldrip, Piroon Jenjaroenpun, Oktawia DeYoung, Intawat Nookaew, Sean D Taverna, Kevin D Raney

PeerJ· July 2020

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Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro.
Thomas J Butler, Katrina N Estep, Joshua A Sommers, Robert W Maul, Ann Zenobia Moore, Kevin D Raney

Hum Mol Genet· May 2020

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Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles.
Anupam Singh, Manjula Pandey, Divya Nandakumar, Kevin D Raney, Y Whitney Yin

EMBO J· March 2020

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Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases.
Nannan Su, Alicia K Byrd, Sakshibeedu R Bharath, Olivia Yang, Yu Jia, Kevin D Raney

Nat Commun· November 2019

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Direct quantification of the translocation activities of Saccharomyces cerevisiae Pif1 helicase.
Chen Lu, Shimin Le, Jin Chen, Alicia K Byrd, Daniela Rhodes, Kevin D Raney

Nucleic Acids Res· August 2019

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DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA.
Jun Gao, Alicia K Byrd, Boris L Zybailov, John C Marecki, Michael J Guderyon, Kevin D Raney

Chem Commun (Camb)· April 2019

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