Publications by authors named "Kevin D Wells"

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Pre-Existing Anti-Adeno-Associated Virus Immunity in Gene Therapy: Mechanisms, Challenges, and Potential Solutions.
Godwin I Iroanya, Pradeep N Subramanyam, Kevin D Wells, Jonathan A Green

Hum Gene Ther· December 2025

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Programming of the endometrial immune milieu by interferon gamma during early pregnancy in pigs†.
Mariana Sponchiado, Weihong Gu, Darling Melany de C Madrid, Rachel A Carroll, Kimberly M Davenport, Kevin D Wells

Biol Reprod· December 2025

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Efficient mammalian neuron editing using peptide-mediated CRISPR enzyme delivery.
Brigette D Manohar, Meika Travis, Vikas Munjal, Christopher M Baehr, Lily M A Rahnama, Kevin D Wells

bioRxiv· November 2025

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A porcine model of Fanconi anemia.
Brandon Hergert, Kristin M Whitworth, Devorah C Goldman, Lisa Moreau, Kelsey McQueen, Kevin D Wells

PLoS One· October 2025

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RHO1-2 meganuclease gene editing targets human P23H rhodopsin-induced retinitis pigmentosa to rejuvenate rods and maintain cones.
Archana Jalligampala, Jacob M Young, Jack Feist, Wei Wang, Francesca Barone, Kevin D Wells

bioRxiv· September 2025

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Expression of tripartite motif family-like protein 1 and 2 in early conceptus development and placentation in the pig.
Emily K Eitel, Mariana Sponchiado, Riley M Sullivan, Caroline G Lucas, Bethany K Redel, Kevin D Wells

Reprod Fertil· April 2025

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Gene editing of pigs to control influenza A virus infections.
Taeyong Kwon, Bianca L Artiaga, Chester D McDowell, Kristin M Whitworth, Kevin D Wells

Emerg Microbes Infect· December 2024

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Extended survival of 9- and 10-gene-edited pig heart xenografts with ischemia minimization and CD154 costimulation blockade-based immunosuppression.
Ryan Chaban, Ikechukwu Ileka, Gannon McGrath, Kohei Kinoshita, Zahra Habibabady, Kevin D Wells

J Heart Lung Transplant· December 2024

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Oral fluid testing can be used to monitor xenotransplant donor herds for porcine cytomegalovirus/roseolovirus status.
Susan K Schommer, Melissa S Samuel, Kristin M Whitworth, Addison K Byrne, Kevin D Wells

Front Vet Sci· December 2024

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Conceptus estrogen and prostaglandins provide the maternal recognition of pregnancy signal to prevent luteolysis during early pregnancy in the pig†.
Riley M Sullivan, Caroline G Lucas, Mariana Sponchiado, Emily K Eitel, Lee D Spate, Kevin D Wells

Biol Reprod· October 2024

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Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency.
Kaylynn Monarch, Junchul Yoon, Kyungjun Uh, Emily Reese, Diana Canaveral Restrepo, Kevin D Wells

Lab Anim (NY)· October 2024

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Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells.
Katarina Kulhankova, Anna X Cheng, Soumba Traore, Maud Auger, Mia Pelletier, Kevin D Wells

Nucleic Acids Res· October 2024

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Gene editing of pigs to control influenza A virus infections.
Taeyong Kwon, Bianca L Artiaga, Chester D McDowell, Kristin M Whitworth, Kevin D Wells

bioRxiv· January 2024

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Porcine-specific expression of the three functional CYP19 paralogs in early conceptus, placenta, and gonads.
Caroline Gomes Lucas, Riley M Sullivan, Caroline A Pfeiffer, Paula R Chen, JaeWoo Kim, Kevin D Wells

Reproduction· October 2023

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Gene editing provides a tool to investigate genes involved in reproduction of pigs.
Rodney D Geisert, Destiny N Johns, Caroline A Pfeiffer, Riley M Sullivan, Caroline G Lucas, Kevin D Wells

Mol Reprod Dev· July 2023

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Profiling development of abdominal organs in the pig.
George C Gabriel, William A Devine, Bethany K Redel, Kristin M Whitworth, Melissa Samuel, Kevin D Wells

Sci Rep· September 2022

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Chloride channel accessory 1 gene deficiency causes selective loss of mucus production in a new pig model.
Shamus P Keeler, Jennifer Yantis, Benjamin J Gerovac, Samuel L Youkilis, Stephanie Podgorny, Kevin D Wells

Am J Physiol Lung Cell Mol Physiol· June 2022

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Improvements in pig agriculture through gene editing.
Kristin M Whitworth, Jonathan A Green, Bethany K Redel, Rodney D Geisert, Kiho Lee, Kevin D Wells

CABI Agric Biosci· June 2022

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Future of biomedical, agricultural, and biological systems research using domesticated animals.
Thomas E Spencer, Kevin D Wells, Kiho Lee, Bhanu P Telugu, Peter J Hansen

Biol Reprod· April 2022

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Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection.
Paula R Chen, Raymond R R Rowland, Ana M Stoian, Vlad Petrovan, Maureen Sheahan, Kevin D Wells

Sci Rep· March 2022

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Conceptus interferon gamma is essential for establishment of pregnancy in the pig†.
Destiny N Johns, Caroline G Lucas, Caroline A Pfeiffer, Paula R Chen, Ashley E Meyer, Kevin D Wells

Biol Reprod· December 2021

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Serologic titers to Leptospira in vaccinated pigs and interpretation for surveillance.
Susan K Schommer, Nicholas Harrison, Michael Linville, Melissa S Samuel, Sabrina L Hammond, Kevin D Wells

PLoS One· December 2021

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Disrupting porcine glutaminase does not block preimplantation development and elongation nor decrease mTORC1 activation in conceptuses†.
Paula R Chen, Caroline G Lucas, Raissa F Cecil, Caroline A Pfeiffer, Melissa A Fudge, Kevin D Wells

Biol Reprod· November 2021

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Cardiovascular Development and Congenital Heart Disease Modeling in the Pig.
George C Gabriel, William Devine, Bethany K Redel, Kristin M Whitworth, Melissa Samuel, Kevin D Wells

J Am Heart Assoc· July 2021

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The NIH Somatic Cell Genome Editing program.
Krishanu Saha, Erik J Sontheimer, P J Brooks, Melinda R Dwinell, Charles A Gersbach, Kevin D Wells

Nature· April 2021

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