Publications by authors named "Kevin M Crofton"

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European Food Safety Authority database for developmental neurotoxicity studies of pesticides.
Iris Mangas, Eliana Spilioti, Andrea Terron, Martina Panzarea, Monica Nepal, Kevin M Crofton

Crit Rev Toxicol· August 2025

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Developmental neurotoxicity (DNT): A call for implementation of new approach methodologies for regulatory purposes: Summary of the 5th International Conference on DNT Testing.
Ivana Celardo, Michael Aschner, Randolph S Ashton, Kelly E Carstens, Andrea Cediel-Ulloa, Kevin M Crofton

ALTEX· April 2025

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A developmental neurotoxicity adverse outcome pathway (DNT-AOP) with voltage gate sodium channel (VGSC) inhibition as a molecular initiating event (MiE).

EFSA J· August 2024

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Establishment of a human cell-based in vitro battery to assess developmental neurotoxicity hazard of chemicals.
Jonathan Blum, Stefan Masjosthusmann, Kristina Bartmann, Farina Bendt, Xenia Dolde, Kevin M Crofton

Chemosphere· January 2023

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Current status and future directions for a neurotoxicity hazard assessment framework that integrates approaches.
Kevin M Crofton, Arianna Bassan, Mamta Behl, Yaroslav G Chushak, Ellen Fritsche

Comput Toxicol· May 2022

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Evaluating Confidence in Toxicity Assessments Based on Experimental Data and Predictions.
Candice Johnson, Lennart T Anger, Romualdo Benigni, David Bower, Frank Bringezu, Kevin M Crofton

Comput Toxicol· February 2022

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The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.
Ann M Richard, Ruili Huang, Suramya Waidyanatha, Paul Shinn, Bradley J Collins, Kevin M Crofton

Chem Res Toxicol· February 2021

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Harmonized Cross-Species Assessment of Endocrine and Metabolic Disruptors by Ecotox FACTORIAL Assay.
Alexander V Medvedev, Lyubov A Medvedeva, Elena Martsen, Mathew Moeser, Kristen L Gorman, Kevin M Crofton

Environ Sci Technol· October 2020

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Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches.
Pamela D Noyes, Katie Paul Friedman, Patience Browne, Jonathan T Haselman, Mary E Gilbert, Kevin M Crofton

Environ Health Perspect· September 2019

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Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library.
Katie Paul-Friedman, Matt Martin, Kevin M Crofton, Chia-Wen Hsu, Srilatha Sakamuru

Environ Health Perspect· September 2019

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International Regulatory and Scientific Effort for Improved Developmental Neurotoxicity Testing.
Magdalini Sachana, Anna Bal-Price, Kevin M Crofton, Susanne H Bennekou, Timothy J Shafer

Toxicol Sci· January 2019

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Corrigendum to Recommendation on test readiness criteria for new approach methods in toxicology: exemplified for developmental neurotoxicity.
Anna Bal-Price, Helena T Hogberg, Kevin M Crofton, Mardas Daneshian, Rex E FitzGerald

ALTEX· January 2019

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Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity.
Anna Bal-Price, Helena T Hogberg, Kevin M Crofton, Mardas Daneshian, Rex E FitzGerald

ALTEX· November 2018

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The US Federal Tox21 Program: A strategic and operational plan for continued leadership.
Russell S Thomas, Richard S Paules, Anton Simeonov, Suzanne C Fitzpatrick, Kevin M Crofton

ALTEX· October 2018

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Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.
Ellen Fritsche, Philippe Grandjean, Kevin M Crofton, Michael Aschner, Alan Goldberg

Toxicol Appl Pharmacol· September 2018

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OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist

ALTEX· August 2018

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Effects of an environmentally-relevant mixture of pyrethroid insecticides on spontaneous activity in primary cortical networks on microelectrode arrays.
Andrew F M Johnstone, Jenna D Strickland, Kevin M Crofton, Chris Gennings, Timothy J Shafer

Neurotoxicology· May 2017

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Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations.
Gillian R Langley, Ian M Adcock, François Busquet, Kevin M Crofton, Elena Csernok

Drug Discov Today· February 2017

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FutureTox III: Bridges for Translation.
Daland R Juberg, Thomas B Knudsen, Miriam Sander, Nancy B Beck, Elaine M Faustman, Kevin M Crofton

Toxicol Sci· January 2017

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Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens".
Keith A Houck, Richard S Judson, Thomas B Knudsen, Matthew T Martin, Ann M Richard, Kevin M Crofton

Environ Health Perspect· January 2017

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The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions.
Ila Cote, Melvin E Andersen, Gerald T Ankley, Stanley Barone, Linda S Birnbaum, Kevin M Crofton

Environ Health Perspect· November 2016

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Expanding the test set: Chemicals with potential to disrupt mammalian brain development.
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert

Neurotoxicol Teratol· October 2016

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ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology.
Ann M Richard, Richard S Judson, Keith A Houck, Christopher M Grulke, Patra Volarath, Kevin M Crofton

Chem Res Toxicol· August 2016

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Environmentally relevant pyrethroid mixtures: A study on the correlation of blood and brain concentrations of a mixture of pyrethroid insecticides to motor activity in the rat.
Michael F Hughes, David G Ross, James M Starr, Edward J Scollon, Marcelo J Wolansky, Kevin M Crofton

Toxicology· June 2016

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Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
Katie Paul Friedman, Eric D Watt, Michael W Hornung, Joan M Hedge, Richard S Judson, Kevin M Crofton

Toxicol Sci· May 2016

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