Publications by authors named "Kevin P Bateman"

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Molecular Structure and Mass Spectral Data Quality-Driven Processing of High-Resolution Mass Spectrometry for Quantitative Analysis.
Fabien Fontaine, Luca Morettoni, Ken Anderson, Bernard Choi, Ismael Zamora, Kevin P Bateman

Rapid Commun Mass Spectrom· February 2025

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High-Throughput Covalent Modifier Screening with Acoustic Ejection Mass Spectrometry.
Xiujuan Wen, Chang Liu, Kiersten Tovar, Patrick Curran, Matthew Richards, Kevin P Bateman

J Am Chem Soc· July 2024

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Automated Bioanalytical Workflow for Ligand Binding-Based Pharmacokinetic Assay Development.
Brad R Evans, Armen G Beck, Lai Yeung, Annie Li, Dong Hun Lee, Kevin P Bateman

Anal Chem· January 2024

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Quantitative LC-MS/MS. 1. Impact of Points across a Peak on the Accuracy and Precision of Peak Area Measurements.
Wei Zeng, Kevin P Bateman

J Am Soc Mass Spectrom· June 2023

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Ultrahigh-Throughput Intact Protein Analysis with Acoustic Ejection Mass Spectrometry.
Adway O Zacharias, Chang Liu, Zachary L VanAernum, Thomas R Covey, Kevin P Bateman

J Am Soc Mass Spectrom· January 2023

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Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes.
Nanyan Rena Zhang, Nathan G Hatcher, Kim Ekroos, Komal Kedia, Monika Kandebo, Kevin P Bateman

J Lipid Res· June 2022

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A Model-Based Approach to Bridging Plasma and Dried Blood Spot Concentration Data for Phase 3 Verubecestat Trials.
Marissa F Dockendorf, David Jaworowicz, Rebecca Humphrey, Melanie Anderson, Sheila Breidinger, Kevin P Bateman

AAPS J· April 2022

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An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat.
Melanie Anderson, Marissa F Dockendorf, Ian McIntosh, Iris Xie, Sheila Breidinger, Kevin P Bateman

AAPS J· April 2022

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Intact Mass Quantitation of Therapeutic Antibodies for Pharmacokinetic Studies Using Immuno-Purification.
Lisa A Vasicek, Daniel S Spellman, Kevin P Bateman

Methods Mol Biol· January 2022

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Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics, and Biotransformation in Preclinical and Clinical Studies: An Industry Perspective.
John F Kellie, John C Tran, Wenying Jian, Barry Jones, John T Mehl, Kevin P Bateman

J Am Soc Mass Spectrom· August 2021

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Direct Analysis from Phase-Separated Liquid Samples using ADE-OPI-MS: Applicability to High-Throughput Screening for Inhibitors of Diacylglycerol Acyltransferase 2.
Xiujuan Wen, Chang Liu, Lucien Ghislain, Kiersten Tovar, Vinit Shah, Kevin P Bateman

Anal Chem· April 2021

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Digitally Enabled, Patient-Centric Clinical Trials: Shifting the Drug Development Paradigm.
Marissa F Dockendorf, Bryan J Hansen, Kevin P Bateman, Matthew Moyer, Jyoti K Shah

Clin Transl Sci· March 2021

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Volumetric absorptive microsampling (VAMS®) in therapeutic protein quantification by LC-MS/MS: Investigation of anticoagulant impact on assay performance and recommendations for best practices in method development.
Xinliu Gao, Cindy Chen, Dong Geng, Kevin P Bateman, Shuangping Shi

J Pharm Biomed Anal· March 2021

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Development of an automated and High throughput UHPLC/MS based workflow for cleaning verification of potent compounds in the pharmaceutical manufacturing environment.
Huaming Sheng, Dae Kim, Alexander S Chin, Yuejie Zhao, Yong Liu, Kevin P Bateman

J Pharm Biomed Anal· September 2020

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The development of patient-centric sampling as an enabling technology for clinical trials.
Kevin P Bateman

Bioanalysis· July 2020

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IQ consortium perspective: complementary LBA and LC-MS in protein therapeutics bioanalysis and biotransformation assessment.
Surinder Kaur, Kevin P Bateman, Jim Glick, Mark Jairaj, John F Kellie

Bioanalysis· February 2020

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Direct quantitation of therapeutic antibodies for pharmacokinetic studies using immuno-purification and intact mass analysis.
Lisa A Vasicek, Xin Zhu, Daniel S Spellman, Kevin P Bateman

Bioanalysis· February 2019

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Leveraging Digital Health Technologies and Outpatient Sampling in Clinical Drug Development: A Phase I Exploratory Study.
Marissa F Dockendorf, Gowri Murthy, Kevin P Bateman, Prajakti A Kothare, Melanie Anderson

Clin Pharmacol Ther· January 2019

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Microdosing Cocktail Assay Development for Drug-Drug Interaction Studies.
Cynthia M Chavez-Eng, Ryan W Lutz, Dina Goykhman, Kevin P Bateman

J Pharm Sci· July 2018

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Extractability-mediated stability bias and hematocrit impact: High extraction recovery is critical to feasibility of volumetric adsorptive microsampling (VAMS) in regulated bioanalysis.
Iris Xie, Yang Xu, Melanie Anderson, Ming Wang, Lingling Xue, Kevin P Bateman

J Pharm Biomed Anal· July 2018

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Top-down LC-MS quantitation of intact denatured and native monoclonal antibodies in biological samples.
Liyun Zhang, Lisa A Vasicek, SuChun Hsieh, Shuli Zhang, Kevin P Bateman

Bioanalysis· July 2018

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Population PK Analyses of Ubrogepant (MK-1602), a CGRP Receptor Antagonist: Enriching In-Clinic Plasma PK Sampling With Outpatient Dried Blood Spot Sampling.
Chi-Chung Li, Marissa Dockendorf, Ken Kowalski, Bei Yang, Yang Xu, Kevin P Bateman

J Clin Pharmacol· March 2018

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Quantitation of a Therapeutic Antibody in Serum Using Intact Sequential Affinity Capture, Trypsin Digestion, and LC-MS/MS.
Lisa A Vasicek, Daniel S Spellman, SuChun Hsieh, Wolfgang Seghezzi, Shuli Zhang, Kevin P Bateman

Anal Chem· January 2018

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Using miniature MS system with automatic blood sampler for preclinical pharmacokinetics study.
Fan Pu, Wenpeng Zhang, Kevin P Bateman, Yong Liu, Roy Helmy

Bioanalysis· November 2017

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Insulin glargine and its two active metabolites: A sensitive (16pM) and robust simultaneous hybrid assay coupling immunoaffinity purification with LC-MS/MS to support biosimilar clinical studies.
Yang Xu, Li Sun, Melanie Anderson, Philippe Bélanger, Vincent Trinh, Kevin P Bateman

J Chromatogr B Analyt Technol Biomed Life Sci· September 2017

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