Publications by authors named "Key-Hwan Lim"

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CRISPR editing of miR-33 restores ApoE lipidation and amyloid-β metabolism in ApoE4 sporadic Alzheimer's disease.
Boyoung Kim, Minju Yuk, Moonsu Park, Hongji Ryu, Junhang Park, Key-Hwan Lim

Brain· December 2025

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CRISPRa Lipid Nanocomplex-Mediated Mt3 Targeting Enhances Astrocytic Endocytosis of Amyloid-β in an Alzheimer's Disease Mouse Model.
Junhang Park, Boyoung Kim, Minki Ha, Moonsu Park, Hongji Ryu, Key-Hwan Lim

Adv Sci (Weinh)· December 2025

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CHI3L1 promotes cell division through activation of RhoA in lung cancer cells.
Ji Eun Yu, Jung-Hyun Shim, In Jun Yeo, Dong Ju Son, Jaesuk Yun, Key-Hwan Lim

Cell Commun Signal· December 2025

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Chitinase-3-Like Protein 1 as a Therapeutic Target for Inflammatory Diseases.
Sun Mi Gu, Tae Hun Kim, Jeong Ho Park, Key-Hwan Lim, Po Myoung Jun

Biomol Ther (Seoul)· September 2025

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A genome-wide association study for lifetime estrogen exposure identifies novel loci and polygenic signals in East Asian postmenopausal women.
Minju Yuk, Soyoun Yang, Dabin Yun, Kwangyeon Oh, Ji Min Han, Key-Hwan Lim

Maturitas· August 2025

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Preclinical studies and transcriptome analysis in a model of Parkinson's disease with dopaminergic ZNF746 expression.
Ji Hun Kim, Sumin Yang, Hyojung Kim, Dang-Khoa Vo, Han-Joo Maeng, Key-Hwan Lim

Mol Neurodegener· February 2025

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Targeted demethylation of cathepsin D via epigenome editing rescues pathology in Alzheimer's disease mouse model.
Moonsu Park, Hongji Ryu, Suyeon Heo, Boyoung Kim, Junhang Park, Key-Hwan Lim

Theranostics· January 2025

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Transport of Golgi-localized β-catenin p-S47 by KIF11 or KIFC3 induces primary ciliogenesis.
Na Yeong Lee, Mi-Lang Kyun, Ji Eun Yu, Sun-Ok Kim, Key-Hwan Lim

Mol Cells· December 2024

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Ingenol-3-Angelate Enhances the B Cell Inhibitory Potential of Mesenchymal Stem Cells, Leading to Marked Alleviation of Lupus Symptoms in MRL. Mice.
Hong Kyung Lee, Hwa Kyung Kim, Ji Yeon Kim, Ji Su Kim, JinKyung Park, Key-Hwan Lim

Int J Mol Sci· November 2024

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Corrigendum to "(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol alleviates inflammatory responses in LPS-induced mice liver sepsis through inhibition of STAT3 phosphorylation" [Int. Immunopharmacol. 125(Part B) (2023) 111124].
Boyoung Kim, Ji Eun Yu, In Jun Yeo, Dong Ju Son, Hee Pom Lee, Key-Hwan Lim

Int Immunopharmacol· August 2024

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Self-Reported Findings of the Korean Intermittent Exotropia Multicenter Study Questionnaire.
Hee Kyung Yang, Shin Hae Park, Haeng-Jin Lee, Sook-Young Kim, Hyo Jung Gye, Key Hwan Lim

Korean J Ophthalmol· June 2024

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Developing theragnostics for Alzheimer's disease: Insights from cancer treatment.
Hyun-Ju Lee, Hee-Jeong Choi, Yoo Joo Jeong, Yoon-Hee Na, Jin Tae Hong, Key-Hwan Lim

Int J Biol Macromol· June 2024

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(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol alleviates inflammatory responses in LPS-induced mice liver sepsis through inhibition of STAT3 phosphorylation.
Boyoung Kim, Ji Eun Yu, In Jun Yeo, Dong Ju Son, Hee Pom Lee, Key-Hwan Lim

Int Immunopharmacol· December 2023

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Cryptic mutations of PLC family members in brain disorders: recent discoveries and a deep-learning-based approach.
Key-Hwan Lim, Sumin Yang, Sung-Hyun Kim, Euiseong Ko, Mingon Kang

Brain· April 2023

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Boosting of tau protein aggregation by CD40 and CD48 gene expression in Alzheimer's disease.
Sung-Hyun Kim, Key-Hwan Lim, Sumin Yang, Jae-Yeol Joo

FASEB J· January 2023

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Prediction of genetic alteration of phospholipase C isozymes in brain disorders: Studies with deep learning.
Jae-Yeol Joo, Key-Hwan Lim, Sumin Yang, Sung-Hyun Kim, Lucio Cocco

Adv Biol Regul· December 2021

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An Overview of the Korean Intermittent Exotropia Multicenter Study by the Korean Association for Pediatric Ophthalmology and Strabismus.
Dae Hee Kim, Seung-Hee Baek, Hee-Young Choi, Dong Gyu Choi, Dong Cheol Lee, Han Woong Lim, Hyun Taek Lim, Key Hwan Lim

Korean J Ophthalmol· October 2021

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Identifying New COVID-19 Receptor Neuropilin-1 in Severe Alzheimer's Disease Patients Group Brain Using Genome-Wide Association Study Approach.
Key-Hwan Lim, Sumin Yang, Sung-Hyun Kim, Jae-Yeol Joo

Front Genet· October 2021

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Long non-coding RNAs in brain tumors: roles and potential as therapeutic targets.
Sung-Hyun Kim, Key-Hwan Lim, Sumin Yang, Jae-Yeol Joo

J Hematol Oncol· May 2021

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Molecular landscape of long noncoding RNAs in brain disorders.
Sumin Yang, Key-Hwan Lim, Sung-Hyun Kim, Jae-Yeol Joo

Mol Psychiatry· April 2021

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Advances in multiplex PCR for Alzheimer's disease diagnostics targeting CDK genes.
Key-Hwan Lim, Sung-Hyun Kim, Sumin Yang, Sungkun Chun, Jae-Yeol Joo

Neurosci Lett· April 2021

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Prediction of Alzheimer's disease-specific phospholipase c gamma-1 SNV by deep learning-based approach for high-throughput screening.
Sung-Hyun Kim, Sumin Yang, Key-Hwan Lim, Euiseng Ko, Hyun-Jun Jang

Proc Natl Acad Sci U S A· January 2021

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Discoveries for Long Non-Coding RNA Dynamics in Traumatic Brain Injury.
Key-Hwan Lim, Sumin Yang, Sung-Hyun Kim, Sungkun Chun, Jae-Yeol Joo

Biology (Basel)· December 2020

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Elevation of ACE2 as a SARS-CoV-2 entry receptor gene expression in Alzheimer's disease.
Key-Hwan Lim, Sumin Yang, Sung-Hyun Kim, Jae-Yeol Joo

J Infect· September 2020

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The potential roles of deubiquitinating enzymes in brain diseases.
Key-Hwan Lim, Jae-Yeol Joo, Kwang-Hyun Baek

Ageing Res Rev· August 2020

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