Publications by authors named "Kiersten Ruff"

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Nuclear speckle proteins form intrinsic and MALAT1-dependent microphases.
Min Kyung Shinn, Dylan T Tomares, Vicky Liu, Avnika Pant, Yuanxin Qiu, Kiersten M Ruff

Cell· December 2025

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Investigating the role of the I-II linker in Nav1.5 channel function.
Emily Wagner, Martina Marras, Shashi Kumar, Jacob Kelley, Kiersten Ruff

J Gen Physiol· November 2025

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Molecular grammars of predicted intrinsically disordered regions that span the human proteome.
Kiersten M Ruff, Matthew R King, Alexander W Ying, Vicky Liu, Avnika Pant

Cell· November 2025

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YAP charge patterning mediates signal integration through transcriptional co-condensates.
Kirstin Meyer, Klaus Yserentant, Rasmi Cheloor-Kovilakam, Kiersten M Ruff, Chan-I Chung

Nat Commun· August 2025

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Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation.
Tapojyoti Das, Fatima K Zaidi, Mina Farag, Kiersten M Ruff, Tharun Selvam Mahendran

Mol Cell· June 2025

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Synapsin Condensation is Governed by Sequence-Encoded Molecular Grammars.
Christian Hoffmann, Kiersten M Ruff, Irina A Edu, Min Kyung Shinn, Johannes V Tromm

J Mol Biol· April 2025

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Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation.
Tapojyoti Das, Fatima K Zaidi, Mina Farag, Kiersten M Ruff, Tharun Selvam Mahendran

bioRxiv· March 2025

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Nuclear speckle proteins form intrinsic and -dependent microphases.
Min Kyung Shinn, Dylan T Tomares, Vicky Liu, Avnika Pant, Yuanxin Qiu, Kiersten M Ruff

bioRxiv· February 2025

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Molecular grammars of intrinsically disordered regions that span the human proteome.
Kiersten M Ruff, Matthew R King, Alexander W Ying, Vicky Liu, Avnika Pant

bioRxiv· February 2025

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Emergent microenvironments of nucleoli.
Matthew R King, Kiersten M Ruff, Rohit V Pappu

Nucleus· December 2024

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Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
Andrea Holla, Erik W Martin, Thomas Dannenhoffer-Lafage, Kiersten M Ruff, Sebastian L B König

JACS Au· December 2024

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Synapsin condensation is governed by sequence-encoded molecular grammars.
Christian Hoffmann, Kiersten M Ruff, Irina Edu, Min Kyung Shinn, Johannes Tromm

bioRxiv· October 2024

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YAP charge patterning mediates signal integration through transcriptional co-condensates.
Kirstin Meyer, Klaus Yserentant, Rasmi Cheloor-Kovilakam, Kiersten M Ruff, Chan-I Chung

bioRxiv· August 2024

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Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient.
Matthew R King, Kiersten M Ruff, Andrew Z Lin, Avnika Pant, Mina Farag

Cell· April 2024

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Dynamical control enables the formation of demixed biomolecular condensates.
Andrew Z Lin, Kiersten M Ruff, Furqan Dar, Ameya Jalihal, Matthew R King

Nat Commun· November 2023

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A disordered region controls cBAF activity via condensation and partner recruitment.
Ajinkya Patil, Amy R Strom, Joao A Paulo, Clayton K Collings, Kiersten M Ruff

Cell· October 2023

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SOURSOP: A Python Package for the Analysis of Simulations of Intrinsically Disordered Proteins.
Jared M Lalmansingh, Alex T Keeley, Kiersten M Ruff, Rohit V Pappu, Alex S Holehouse

J Chem Theory Comput· August 2023

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Dynamical control enables the formation of demixed biomolecular condensates.
Andrew Z Lin, Kiersten M Ruff, Ameya Jalihal, Furqan Dar, Matthew R King

Res Sq· February 2023

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SOURSOP: A Python package for the analysis of simulations of intrinsically disordered proteins.
Jared M Lalmansingh, Alex T Keeley, Kiersten M Ruff, Rohit V Pappu, Alex S Holehouse

bioRxiv· February 2023

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Dynamical control enables the formation of demixed biomolecular condensates.
Andrew Z Lin, Kiersten M Ruff, Ameya Jalihal, Furqan Dar, Matthew R King

bioRxiv· January 2023

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Connecting sequence features within the disordered C-terminal linker of FtsZ to functions and bacterial cell division.
Min Kyung Shinn, Megan C Cohan, Jessie L Bullock, Kiersten M Ruff, Petra A Levin

Proc Natl Acad Sci U S A· October 2022

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Sequence grammar underlying the unfolding and phase separation of globular proteins.
Kiersten M Ruff, Yoon Hee Choi, Dezerae Cox, Angelique R Ormsby, Yoochan Myung

Mol Cell· September 2022

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Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins.
Xiangze Zeng, Kiersten M Ruff, Rohit V Pappu

Proc Natl Acad Sci U S A· May 2022

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AlphaFold and Implications for Intrinsically Disordered Proteins.
Kiersten M Ruff, Rohit V Pappu

J Mol Biol· October 2021

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Polyphasic linkage and the impact of ligand binding on the regulation of biomolecular condensates.
Kiersten M Ruff, Furqan Dar, Rohit V Pappu

Biophys Rev (Melville)· June 2021

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