Publications by authors named "Killian Hanlon"

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Rapid kinetics of AAV8 delivery of Vglut3 and hearing rescue shown day-by-day via matched IHC and ABR.
Cole W D Peters, Killian Hanlon

Mol Ther Methods Clin Dev· December 2025

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Engineered AAV capsids mediate transduction of murine neurofibroma and sciatic nerve.
Edwina Abou Haidar, Shilpa Prabhakar, Pike See Cheah, Killian S Hanlon, Paula Espinoza

Gene Ther· July 2025

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Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice.
Miguel C Santoscoy, Paula Espinoza, Killian S Hanlon, Luna Yang, Lisa Nieland

bioRxiv· September 2024

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In vivo selection in non-human primates identifies AAV capsids for on-target CSF delivery to spinal cord.
Killian S Hanlon, Ming Cheng, Roberto Montoro Ferrer, Jae Ryun Ryu, Boram Lee

Mol Ther· August 2024

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selection in non-human primates identifies superior AAV capsids for on-target CSF delivery to spinal cord.
Killian S Hanlon, Ming Cheng, Demitri De La Cruz, Nikita Patel, Miguel C Santoscoy

bioRxiv· September 2023

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Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F.
Cole W Peters, Killian S Hanlon, Maryna V Ivanchenko, Eric Zinn, Elizabeth F Linarte

Mol Ther· August 2023

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An Engineered Adeno-Associated Virus Capsid Mediates Efficient Transduction of Pericytes and Smooth Muscle Cells of the Brain Vasculature.
Servio H Ramirez, Jonathan F Hale, Siobhan McCarthy, Christian L Cardenas, Kalpani N Udeni Galpayage Dona, Killian S Hanlon

Hum Gene Ther· August 2023

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Genomic investigations of unexplained acute hepatitis in children.
Sofia Morfopoulou, Sarah Buddle, Oscar Enrique Torres Montaguth, Laura Atkinson, José Afonso Guerra-Assunção, Killian S Hanlon

Nature· May 2023

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Optimisation of AAV-NDI1 Significantly Enhances Its Therapeutic Value for Correcting Retinal Mitochondrial Dysfunction.
Naomi Chadderton, Arpad Palfi, Daniel M Maloney, Matthew Carrigan, Laura K Finnegan, Killian S Hanlon

Pharmaceutics· January 2023

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The AAV9 Variant Capsid AAV-F Mediates Widespread Transgene Expression in Nonhuman Primate Spinal Cord After Intrathecal Administration.
Adam Beharry, Yi Gong, James C Kim, Killian S Hanlon, Josette Nammour

Hum Gene Ther· January 2022

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Delivering AAV to the Central Nervous and Sensory Systems.
Cole W Peters, Casey A Maguire, Killian S Hanlon

Trends Pharmacol Sci· June 2021

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AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear.
Maryna V Ivanchenko, Killian S Hanlon, Daniel M Hathaway, Alex J Klein, Cole W Peters

Mol Ther Methods Clin Dev· June 2021

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Versatile Role of Rab27a in Glioma: Effects on Release of Extracellular Vesicles, Cell Viability, and Tumor Progression.
Thomas S van Solinge, Erik R Abels, Lieke L van de Haar, Killian S Hanlon, Sybren L N Maas

Front Mol Biosci· November 2020

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Novel 199 base pair NEFH promoter drives expression in retinal ganglion cells.
Sophia Millington-Ward, Naomi Chadderton, Megan Berkeley, Laura K Finnegan, Killian S Hanlon

Sci Rep· October 2020

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Preclinical testing of AAV9-PHP.B for transgene expression in the non-human primate cochlea.
Maryna V Ivanchenko, Killian S Hanlon, Maya K Devine, Kelly Tenneson, Frederick Emond

Hear Res· September 2020

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In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery.
Cort B Breuer, Killian S Hanlon, Jeya-Shree Natasan, Adrienn Volak, Amine Meliani

Sci Rep· March 2020

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Selection of an Efficient AAV Vector for Robust CNS Transgene Expression.
Killian S Hanlon, Jonah C Meltzer, Tetyana Buzhdygan, Ming J Cheng, Miguel Sena-Esteves

Mol Ther Methods Clin Dev· December 2019

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High levels of AAV vector integration into CRISPR-induced DNA breaks.
Killian S Hanlon, Benjamin P Kleinstiver, Sara P Garcia, Mikołaj P Zaborowski, Adrienn Volak

Nat Commun· September 2019

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Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate.
Bence György, Elise J Meijer, Maryna V Ivanchenko, Kelly Tenneson, Frederick Emond, Killian S Hanlon

Mol Ther Methods Clin Dev· June 2019

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A Novel Retinal Ganglion Cell Promoter for Utility in AAV Vectors.
Killian S Hanlon, Naomi Chadderton, Arpad Palfi, Alfonso Blanco Fernandez, Peter Humphries

Front Neurosci· September 2017

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