Publications by authors named "Kim D Janda"

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Solid-phase synthesis of a pyrrole library and identification of bioactive compounds.
Sukhyun Lee, Lisa M Eubanks, Kim D Janda

Bioorg Med Chem Lett· December 2025

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Bifunctional Behavior of Conformationally Constrained Methamphetamine Analogs: Unexpected Heteroclitic Immune Response and Antagonist Effects Altering Methamphetamine and Fentanyl Pharmacology.
Sukhyun Lee, Lisa M Eubanks, Bin Zhou, Kim D Janda

J Med Chem· October 2025

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Bifunctional Inhibition of Botulinum Neurotoxin A Protease: Unexpected Active Site Inhibition Enhances Covalent Targeting of an Allosteric Site.
Mingliang Lin, Nishant Karadkhelkar, Yanjie Li, Lisa M Eubanks, William H Tepp, Kim D Janda

J Med Chem· April 2025

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Investigations of Thiosemicarbazides as Botulinum Toxin Active-Site Inhibitors: Enzyme, Cellular, and Rodent Intoxication Studies.
Ealin N Patel, Lucy Lin, Hyeri Park, Molly M Sneller, Lisa M Eubanks, Kim D Janda

ACS Infect Dis· November 2024

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Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet.
András H Lékó, Adriana Gregory-Flores, Renata C N Marchette, Juan L Gomez, Janaina C M Vendruscolo, Kim D Janda

Commun Biol· May 2024

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Evaluation of a hapten conjugate vaccine against the "zombie drug" xylazine.
Mingliang Lin, Lisa M Eubanks, Bin Zhou, Kim D Janda

Chem Commun (Camb)· April 2024

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Discovery of PLD4 modulators by high-throughput screening and kinetic analysis.
Jinny Claire Lee, Ryan J Shirey, Lewis D Turner, Hyeri Park, Luke L Lairson, Kim D Janda

Results Chem· January 2024

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Pharmacological GHSR (ghrelin receptor) blockade reduces alcohol binge-like drinking in male and female mice.
Rani S Richardson, Agnieszka Sulima, Kenner C Rice, Jed A Kucharczk, Kim D Janda

Neuropharmacology· November 2023

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An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Lisa M Eubanks, Tossapol Pholcharee, David Oyen, Yoshihiro Natori, Bin Zhou, Kim D Janda

ACS Chem Neurosci· August 2023

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An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity that Reverses Carfentanil-Induced Respiratory Depression.
Lisa M Eubanks, Tossapol Pholcharee, David Oyen, Yoshihiro Natori, Bin Zhou, Kim D Janda

bioRxiv· July 2023

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Development of a vaccine against the synthetic opioid U-47700.
Hyeri Park, Mingliang Lin, Jian Zhou, Lisa M Eubanks, Bin Zhou, Kim D Janda

Front Pharmacol· July 2023

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Catalytic Antibody Blunts Carfentanil-Induced Respiratory Depression.
Mingliang Lin, Lisa M Eubanks, Nishant M Karadkhelkar, Steven Blake, Kim D Janda

ACS Pharmacol Transl Sci· May 2023

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Demystifying the Druggability of the MYC Family of Oncogenes.
Nishant M Karadkhelkar, Mingliang Lin, Lisa M Eubanks, Kim D Janda

J Am Chem Soc· February 2023

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Development of an Effective Monoclonal Antibody against Heroin and Its Metabolites Reveals Therapies Have Mistargeted 6-Monoacetylmorphine and Morphine over Heroin.
Jinny Claire Lee, Lisa M Eubanks, Bin Zhou, Kim D Janda

ACS Cent Sci· October 2022

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Polyphosphazene: A New Adjuvant Platform for Cocaine Vaccine Development.
Mingliang Lin, Alexander Marin, Beverly Ellis, Lisa M Eubanks, Alexander K Andrianov, Kim D Janda

Mol Pharm· September 2022

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Investigation of Salicylanilides as Botulinum Toxin Antagonists.
Ealin N Patel, Lucy Lin, Molly M Sneller, Lisa M Eubanks, William H Tepp, Kim D Janda

ACS Infect Dis· August 2022

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Identification of Slow-Binding Inhibitors of the BoNT/A Protease.
Ealin N Patel, Lewis D Turner, Mark S Hixon, Kim D Janda

ACS Med Chem Lett· April 2022

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Development of effective therapeutics for polysubstance use disorders.
Jinny Claire Lee, Kim D Janda

Curr Opin Chem Biol· February 2022

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A Vaccine against Benzimidazole-Derived New Psychoactive Substances That Are More Potent Than Fentanyl.
Jinny Claire Lee, Hyeri Park, Lisa M Eubanks, Beverly Ellis, Bin Zhou, Kim D Janda

J Med Chem· February 2022

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Isoxazole-9 reduces enhanced fear responses and retrieval in ethanol-dependent male rats.
Miranda C Staples, Melissa A Herman, Jonathan W Lockner, Yosef Avchalumov, Khush M Kharidia, Kim D Janda

J Neurosci Res· November 2021

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Modulators of immunoregulatory exonucleases PLD3 and PLD4 identified by high-throughput screen.
Ryan J Shirey, Lewis D Turner, Luke L Lairson, Kim D Janda

Bioorg Med Chem Lett· October 2021

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Salicylanilides Reduce SARS-CoV-2 Replication and Suppress Induction of Inflammatory Cytokines in a Rodent Model.
Steven Blake, Namir Shaabani, Lisa M Eubanks, Junki Maruyama, John T Manning, Kim D Janda

ACS Infect Dis· August 2021

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Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease.
Lewis D Turner, Alexander L Nielsen, Lucy Lin, Antonio J Campedelli, Nicholas R Silvaggi, Kim D Janda

ACS Med Chem Lett· August 2021

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Immunopharmacotherapeutic advancements in addressing methamphetamine abuse.
Jinny Claire Lee, Kim D Janda

RSC Chem Biol· February 2021

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Broadly Neutralizing Synthetic Cannabinoid Vaccines.
Mingliang Lin, Jinny Claire Lee, Steven Blake, Beverly Ellis, Lisa M Eubanks, Kim D Janda

JACS Au· January 2021

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