Publications by authors named "Kim Stever"

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Preclinical and clinical antiviral characterization of AB-836, a potent capsid assembly modulator against hepatitis B virus.
Angela M Lam, Nagraj Mani, Andrzej Ardzinski, Kim Stever, Andrea Cuconati

Antiviral Res· November 2024

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Rational Design, Synthesis, and Structure-Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836.
Andrew G Cole, Steven G Kultgen, Nagraj Mani, Kristi Yi Fan, Andrzej Ardzinski, Kim Stever

J Med Chem· September 2024

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Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators.
Eugen F Mesaros, Andrew G Cole, Steven G Kultgen, Nagraj Mani, Kristi Yi Fan, Kim Stever

ACS Med Chem Lett· September 2024

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Discovery of -Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2.
Eugen F Mesaros, Benjamin J Dugan, Min Gao, Muhammad Sheraz, Kayleigh McGovern-Gooch, Kim Stever

ACS Infect Dis· May 2024

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Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506.
Andrew G Cole, Steven G Kultgen, Nagraj Mani, Jorge G Quintero, Kristi Yi Fan, Kim Stever

Bioorg Med Chem Lett· October 2023

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The identification of highly efficacious functionalised tetrahydrocyclopenta[]pyrroles as inhibitors of HBV viral replication through modulation of HBV capsid assembly.
Andrew G Cole, Steven G Kultgen, Nagraj Mani, Andrzej Ardzinski, Kristi Yi Fan, Kim Stever

RSC Med Chem· March 2022

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Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein.
Nagraj Mani, Andrew G Cole, Janet R Phelps, Andrzej Ardzinski, Robbin Burns, Kim Stever

Antiviral Res· January 2022

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Preclinical Profile of AB-423, an Inhibitor of Hepatitis B Virus Pregenomic RNA Encapsidation.
Nagraj Mani, Andrew G Cole, Janet R Phelps, Andrzej Ardzinski, Kyle D Cobarrubias, Kim Stever

Antimicrob Agents Chemother· June 2018

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