Publications by authors named "Kim-Chew Lim"

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A genome-wide screen identifies genes required for erythroid differentiation.
Greggory Myers, Ann Friedman, Lei Yu, Narges Pourmandi, Claire Kerpet, Kim-Chew Lim

Nat Commun· April 2025

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Murine erythroid differentiation kinetics in vivo under normal and anemic stress conditions.
Greggory Myers, Yu Wang, Qing Wang, Ann Friedman, Alejandra Sanchez-Martinez, Kim-Chew Lim

Blood Adv· October 2023

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Identification of novel γ-globin inducers among all potential erythroid druggable targets.
Lei Yu, Greggory Myers, Emily Schneider, Yu Wang, Raven Mathews, Kim Chew Lim

Blood Adv· June 2022

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Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.
Bingrui Wang, Chenchen Wang, Yang Wan, Jie Gao, Yige Ma, Kim-Chew Lim

Cell Discov· May 2022

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An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
Lei Yu, Greggory Myers, Chia-Jui Ku, Emily Schneider, Yu Wang, Kim-Chew Lim

Blood· November 2021

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GATA3 is essential for separating patterning domains during facial morphogenesis.
Makoto Abe, Timothy C Cox, Anthony B Firulli, Stanley M Kanai, Jacob Dahlka, Kim-Chew Lim

Development· September 2021

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GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through .
Md Riaj Mahamud, Xin Geng, Yen-Chun Ho, Boksik Cha, Yuenhee Kim, Kim-Chew Lim

Development· November 2019

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BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.
Lei Yu, Natee Jearawiriyapaisarn, Mary P Lee, Tomonori Hosoya, Qingqing Wu, Kim-Chew Lim

Genes Dev· December 2018

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A 3' Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Expression.
Takashi Moriguchi, Tomofumi Hoshino, Arvind Rao, Lei Yu, Jun Takai, Kim-Chew Lim

Mol Cell Biol· November 2018

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Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect.
Takashi Moriguchi, Lei Yu, Akihito Otsuki, Keiko Ainoya, Kim-Chew Lim

Mol Cell Biol· September 2016

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Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development.
Xin Geng, Boksik Cha, Md Riaj Mahamud, Kim-Chew Lim, Robert Silasi-Mansat

Dev Biol· January 2016

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A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance.
Chia-Jui Ku, Kim-Chew Lim, Sundeep Kalantry, Ivan Maillard, James Douglas Engel

Genes Dev· September 2015

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The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice.
Shuaiying Cui, Kim-Chew Lim, Lihong Shi, Mary Lee, Natee Jearawiriyapaisarn

Blood· July 2015

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Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes.
Shuaiying Cui, Osamu Tanabe, Michael Sierant, Lihong Shi, Andrew Campbell, Kim-Chew Lim

Blood· February 2015

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Developmental transcriptome analysis of human erythropoiesis.
Lihong Shi, Yu-Hsuan Lin, M C Sierant, Fan Zhu, Shuaiying Cui, Kim-Chew Lim

Hum Mol Genet· September 2014

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PGC-1 coactivator activity is required for murine erythropoiesis.
Shuaiying Cui, Osamu Tanabe, Kim-Chew Lim, H Eric Xu, X Edward Zhou

Mol Cell Biol· June 2014

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A Snail1/Notch1 signalling axis controls embryonic vascular development.
Zhao-Qiu Wu, R Grant Rowe, Kim-Chew Lim, Yongshun Lin, Amanda Willis

Nat Commun· June 2014

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Biased, non-equivalent gene-proximal and -distal binding motifs of orphan nuclear receptor TR4 in primary human erythroid cells.
Lihong Shi, M C Sierant, Katherine Gurdziel, Fan Zhu, Shuaiying Cui, Kim-Chew Lim

PLoS Genet· May 2014

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Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3.
Aaron M Udager, Ajay Prakash, David A Saenz, Martina Schinke, Takashi Moriguchi, Kim-Chew Lim

Gastroenterology· January 2014

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Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning.
Kim-Chew Lim, Tomonori Hosoya, William Brandt, Chia-Jui Ku, Sakie Hosoya-Ohmura

J Clin Invest· October 2012

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UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice.
Keiko Ainoya, Takashi Moriguchi, Shin'ya Ohmori, Tomokazu Souma, Jun Takai, Kim-Chew Lim

Mol Cell Biol· June 2012

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Limited inner ear morphogenesis and neurosensory development are possible in the absence of GATA3.
Jeremy S Duncan, Kim-Chew Lim, James D Engel, Bernd Fritzsch

Int J Dev Biol· December 2011

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An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene.
Sakie Hosoya-Ohmura, Yu-Hsuan Lin, Mary Herrmann, Takashi Kuroha, Arvind Rao, Kim-Chew Lim

Mol Cell Biol· May 2011

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GATA-3 is required for early T lineage progenitor development.
Tomonori Hosoya, Takashi Kuroha, Takashi Moriguchi, Dustin Cummings, Ivan Maillard, Kim-Chew Lim

J Exp Med· December 2009

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Transcription factor GATA-3 is essential for lens development.
Atsuko Maeda, Takashi Moriguchi, Michito Hamada, Manabu Kusakabe, Yuki Fujioka, Kim-Chew Lim

Dev Dyn· September 2009

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