Publications by authors named "Kimberley Wiggins"

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The common IL1A single nucleotide polymorphism rs17561 is a hypomorphic mutation that significantly reduces interleukin-1α release from human blood cells.
Kimberley A Wiggins, Katerina Pyrillou, Melanie Humphry, Adam S Butterworth, Murray Ch Clarke

Immunology· March 2023

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Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Diana Zatreanu, Helen M R Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Kimberley Wiggins

Nat Commun· June 2021

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Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk.
Liam D Cassidy, Andrew R J Young, Christopher N J Young, Elizabeth J Soilleux, Edward Fielder, Kimberley A Wiggins

Nat Commun· January 2020

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IL-1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype.
Kimberley A Wiggins, Aled J Parry, Liam D Cassidy, Melanie Humphry, Steve J Webster

Aging Cell· June 2019

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Senescence utilises inflammatory caspases to drive SASP.
Kimberley A Wiggins, Murray Ch Clarke

Aging (Albany NY)· June 2019

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The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin.
Laura C Burzynski, Melanie Humphry, Katerina Pyrillou, Kimberley A Wiggins, Julie N E Chan

Immunity· April 2019

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Th1 cytokines are more effective than Th2 cytokines at licensing anti-tumour functions in CD40-activated human macrophages in vitro.
Nadia Luheshi, Gareth Davies, Edmund Poon, Kimberley Wiggins, Matthew McCourt

Eur J Immunol· January 2014

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