Publications by authors named "Kin-Hing W Lau"

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Assessment of Feasibility of the M2 Macrophage-Based Adoptive Gene Transfer Strategy for Osteoarthritis with a Mouse Model.
Matilda H-C Sheng, David J Baylink, Charles H Rundle, Kin-Hing William Lau

Cells· July 2025

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Overexpression of miR17 ~ 92 in Myeloid Cells in Mice Increased Bone Mass Through Reduced Bone Resorption and Increased Bone Formation in Sex-Dependent Manner.
Matilda H-C Sheng, Virginia M Stiffel, Jordan Taipia, Charles H Rundle, Kin-Hing William Lau

Calcif Tissue Int· January 2025

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Conditional Deletion of Gremlin-1 in Cathepsin K-expressing Mature Osteoclasts Altered the Skeletal Response to Calcium Depletion in Sex-Dependent Manner.
Matilda H-C Sheng, Charles H Rundle, David J Baylink, Kin-Hing William Lau

Calcif Tissue Int· January 2025

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Microvesicles Released by Osteoclastic Cells Exhibited Chondrogenic, Osteogenic, and Anti-Inflammatory Activities: An Evaluation of the Feasibility of Their Use for Treatment of Osteoarthritis in a Mouse Model.
Matilda H-C Sheng, Charles H Rundle, Kin-Hing William Lau

Cells· January 2025

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Defective bone repletion in aged Balb/cBy mice was caused by impaired osteoblastic differentiation.
Matilda H-C Sheng, Kin-Hing William Lau, Charles H Rundle, Anar Alsunna, Sean M Wilson

J Bone Miner Metab· November 2022

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Calcium released by osteoclastic resorption stimulates autocrine/paracrine activities in local osteogenic cells to promote coupled bone formation.
Abu Shufian Ishtiaq Ahmed, Matilda H C Sheng, Kin-Hing William Lau, Sean M Wilson, M Daniel Wongworawat

Am J Physiol Cell Physiol· May 2022

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A Novel EphA4 Signaling-Based Therapeutic Strategy for Osteoarthritis in Mice.
Virginia M Stiffel, Charles H Rundle, Matilda H-C Sheng, Subhashri Das, Kin-Hing William Lau

J Bone Miner Res· April 2022

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The EphA4 Signaling is Anti-catabolic in Synoviocytes but Pro-anabolic in Articular Chondrocytes.
Virginia M Stiffel, Alexander Thomas, Charles H Rundle, Matilda H-C Sheng, Kin-Hing William Lau

Calcif Tissue Int· December 2020

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Unique anabolic action of stem cell gene therapy overexpressing PDGFB-DSS6 fusion protein in OVX osteoporosis mouse model.
Wanqiu Chen, Samiksha Wasnik, Yawen Fu, Leslie Aranda, Charles H Rundle, Kin-Hing William Lau

Bone Rep· June 2020

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A Mouse Noninvasive Intraarticular Tibial Plateau Compression Loading-Induced Injury Model of Posttraumatic Osteoarthritis.
Virginia Stiffel, Charles H Rundle, Matilda H-C Sheng, Subhashri Das, Kin-Hing William Lau

Calcif Tissue Int· February 2020

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Mechanistic study of the cause of decreased blood 1,25-Dihydroxyvitamin D in sepsis.
Chih-Huang Li, Xiaolei Tang, Samiksha Wasnik, Xiaohua Wang, Jintao Zhang, Kin-Hing William Lau

BMC Infect Dis· December 2019

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Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90 skeletal stem cells in fracture sites.
Samiksha Wasnik, Ram Lakhan, David J Baylink, Charles H Rundle, Yi Xu, Kin-Hing William Lau

Sci Adv· July 2019

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In Vivo Generation of Gut-Homing Regulatory T Cells for the Suppression of Colitis.
Yi Xu, Yanmei Cheng, David J Baylink, Samiksha Wasnik, Gati Goel, Kin-Hing William Lau

J Immunol· June 2019

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Deficient arginase II expression without alteration in arginase I expression attenuated experimental autoimmune encephalomyelitis in mice.
Mariam Choudry, Xiaolei Tang, Tiffany Santorian, Samiksha Wasnik, Jidong Xiao, Kin-Hing William Lau

Immunology· September 2018

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1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.
Samiksha Wasnik, Charles H Rundle, David J Baylink, Mohammad Safaie Yazdi, Edmundo E Carreon, Kin-Hing William Lau

JCI Insight· September 2018

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A novel miR17/protein tyrosine phosphatase-oc/EphA4 regulatory axis of osteoclast activity.
Kin-Hing William Lau, Matilda H-C Sheng

Arch Biochem Biophys· July 2018

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Conditional Disruption of in Osteoclasts Led to Activation of Osteoclasts and Loss of Trabecular Bone In Part Through Suppression of the miR17-Mediated Downregulation of Protein-Tyrosine Phosphatase-oc in Mice.
Kin-Hing William Lau, Virginia M Stiffel, Charles H Rundle, Mehran Amoui, Jordan Tapia

JBMR Plus· October 2017

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Dendritic cells, engineered to overexpress 25-hydroxyvitamin D 1α-hydroxylase and pulsed with a myelin antigen, provide myelin-specific suppression of ongoing experimental allergic encephalomyelitis.
Chih-Huang Li, Jintao Zhang, David J Baylink, Xiaohua Wang, Naga Bharani Goparaju, Kin-Hing William Lau

FASEB J· July 2017

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Unique Regenerative Mechanism to Replace Bone Lost During Dietary Bone Depletion in Weanling Mice.
Matilda H-C Sheng, Kin-Hing William Lau, Ram Lakhan, Abu Shufian Ishtiaq Ahmed, Charles H Rundle

Endocrinology· April 2017

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Effect of aging on stem cells.
Abu Shufian Ishtiaq Ahmed, Matilda Hc Sheng, Samiksha Wasnik, David J Baylink, Kin-Hing William Lau

World J Exp Med· February 2017

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Conditional deletion of IGF-I in osteocytes unexpectedly accelerates bony union of the fracture gap in mice.
Kin-Hing W Lau, Charles H Rundle, Xiao-Dong Zhou, David J Baylink, Matilda H-C Sheng

Bone· November 2016

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Bidirectional ephrin signaling in bone.
Charles H Rundle, Weirong Xing, Kin-Hing William Lau, Subburaman Mohan

Osteoporos Sarcopenia· June 2016

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