Publications by authors named "Kinuko Uno"

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Distinct roles of branched-chain amino acids in the intestinal epithelium: Valine is essential for intestinal stem cell maintenance.
Ayumi Kozai, Yurika Tajima, Yuri Azuma, Yuri Hatanaka, Kinuko Uno

Biochem Biophys Res Commun· October 2025

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Pathophysiological interaction of dextran sodium sulfate-induced colitis and diet-induced hepatic lesions in mice.
Kinuko Uno, Keita Sekiguchi, Noriko Suzuki-Kemuriyama, Takeshi Ohta, Katsuhiro Miyajima

J Toxicol Sci· July 2025

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Evaluation of Serum L-FABP as a Biomarker and Hepatoprotective Effect of L-FABP Using Wild-Type and Human L-FABP Chromosome Transgenic Mice.
Keiichi Ohata, Kanjiro Ryu, Kinuko Uno, Soon Hui Teoh, Takeshi Sugaya

J Am Assoc Lab Anim Sci· May 2025

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High-fat/high-sucrose diet-induced renal changes in obese diabetic mice: a comparison with db/db and KK-Ay mice.
Chika Oki, Kinuko Uno, Tomohiko Sasase, Takahiro Tsutsui, Keita Sekiguchi

J Vet Med Sci· February 2025

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Granulomatous Myocarditis Caused by Candida Spp Infection in a Spontaneously Diabetic Torii Rat.
Kinuko Uno, Soon Hui Teoh, Keita Sekiguchi, Noriko Suzuki-Kemuriyama, Takeshi Ohta

Med Arch· April 2024

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Pathophysiological Features of Rat Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis.
Yasuka Saigo, Kinuko Uno, Tatsuya Ishigure, Tatsumi Odake, Takeshi Ohta

In Vivo· April 2024

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Urinary liver-type fatty acid binding protein is a biomarker reflecting renal damage and the ameliorative effect of drugs at an early stage of histone-induced acute kidney injury.
Keiichi Ohata, Takeshi Sugaya, Hanh Nhung Nguyen, Karin Arai, Yuri Hatanaka, Kinuko Uno

Nephrology (Carlton)· March 2024

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Renal transcriptome analysis of uninephrectomized db/db mice identified a mechanism for the transition to severe diabetic nephropathy.
Mariko Maekawa, Tatsuya Maekawa, Tomohiko Sasase, Takeshi Wakashima, Atsuhiro Uemura, Kinuko Uno

Exp Anim· February 2024

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Effects of salt supplementation in uninephrectomized KK-Ay mice: Examining the potential of a diabetic kidney disease model.
Ryuhei Sano, Kanjiro Ryu, Tomohiko Sasase, Yuichi Shinozaki, Soon Hui Teoh, Kinuko Uno

J Toxicol Sci· November 2023

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Urinary liver-type fatty acid binding protein is increased in the early stages of the disease with a risk of acute kidney injury induced by histone.
Keiichi Ohata, Takeshi Sugaya, Hanh Nhung Nguyen, Yuri Hatanaka, Kinuko Uno

Nephrology (Carlton)· June 2023

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Choline-deficient Diet-induced NAFLD Animal Model Recaptures Core Human Pathophysiology With Similar Gene Co-expression Networks.
Tatsuya Ishigure, Tomohiko Sasase, Marika Tohma, Kinuko Uno, Yasufumi Toriniwa

In Vivo· June 2023

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Effects of extract on nonalcoholic steatohepatitis-like lesions in Sprague Dawley rats fed a choline-deficient, methionine-lowered, l-amino acid-defined diet.
Kinuko Uno, Katsuhiro Miyajima, Shuji Ogawa, Noriko Suzuki-Kemuriyama, Dai Nakae

J Toxicol Pathol· January 2023

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Effects of dietary phosphorus concentration and phosphate salt form on renal tubule function in unilateral nephrectomized rats.
Kikue Mori, Shin-Ichi Katsumata, Katsuhiro Miyajima, Kinuko Uno, Hiroshi Matsuzaki

Nutr Health· August 2022

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Establishment of a new nonalcoholic steatohepatitis model; Ovariectomy exacerbates nonalcoholic steatohepatitis-like pathology in diabetic rats.
Yasuka Saigo, Tomohiko Sasase, Kinuko Uno, Yuichi Shinozaki, Tatsuya Maekawa

J Pharmacol Toxicol Methods· July 2022

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Salt loading with unilateral nephrectomy accelerates decline in glomerular filtration rate in the hypertensive, obese, type 2 diabetic SDT fatty rat model of diabetic kidney disease.
Yuichi Shinozaki, Yuko Katayama, Fuminari Yamaguchi, Tomohisa Suzuki, Kana Watanabe, Kinuko Uno

Clin Exp Pharmacol Physiol· April 2022

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CD44 expression in the bile duct epithelium is related to hepatic fibrosis in nonalcoholic steatohepatitis rats induced by a choline-deficient, methionine-lowered, L-amino acid diet.
Kinuko Uno, Katsuhiro Miyajima, Marika Toma, Noriko Suzuki-Kemuriyama, Dai Nakae

J Toxicol Pathol· April 2022

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Effects of excessive sodium chloride loading in the spontaneously diabetic torii (SDT) fatty rats, a preclinical model of type 2 diabetes mellitus.
Soon Hui Teoh, Katsuhiro Miyajima, Yuichi Shinozaki, Masami Shinohara, Keiichi Ohata, Kinuko Uno

J Toxicol Sci· January 2022

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Correction to: A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a cholinedeficient, methionine-lowered, L-amino acid-defined, high-fat diet.
Noriko Suzuki-Kemuriyama, Akari Abe, Kinuko Uno, Shuji Ogawa, Atsushi Watanabe

Lipids Health Dis· January 2022

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Nonobese mice with nonalcoholic steatohepatitis fed on a choline-deficient, l-amino acid-defined, high-fat diet exhibit alterations in signaling pathways.
Noriko Suzuki-Kemuriyama, Akari Abe, Sae Nakane, Kinuko Uno, Shuji Ogawa

FEBS Open Bio· November 2021

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A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet.
Noriko Suzuki-Kemuriyama, Akari Abe, Kinuko Uno, Shuji Ogawa, Atsushi Watanabe

Lipids Health Dis· December 2020

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Mycotoxin Deoxynivalenol Has Different Impacts on Intestinal Barrier and Stem Cells by Its Route of Exposure.
Hikaru Hanyu, Yuki Yokoi, Kiminori Nakamura, Tokiyoshi Ayabe, Keisuke Tanaka, Kinuko Uno

Toxins (Basel)· September 2020

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Hepatic lesions induced by feeding Western diets to Zucker fatty rats, an insulin-resistant model.
Tomoyuki Saito, Yasufumi Toriniwa, Yukihito Ishii, Atsuhiro Uemura, Katsuhiro Miyajima, Kinuko Uno

J Toxicol Pathol· October 2018

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Investigation of pharmacological responses to anti-diabetic drugs in female Spontaneously Diabetic Torii (SDT) fatty rats, a new nonalcoholic steatohepatitis (NASH) model.
Yasufumi Toriniwa, Tomoyuki Saito, Katsuhiro Miyajima, Yukihito Ishii, Kinuko Uno

J Vet Med Sci· June 2018

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