Publications by authors named "Kirill D Nadezhdin"

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Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein.
Arthur Neuberger, Yury A Trofimov, Maria V Yelshanskaya, Kirill D Nadezhdin, Nikolay A Krylov, Roman G Efremov, Alexander I Sobolevsky

Nat Commun· May 2023

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Forty sites of TRP channel regulation.
Irina A Talyzina, Kirill D Nadezhdin, Alexander I Sobolevsky

Curr Opin Chem Biol· February 2025

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Structure-function analyses of human TRPV6 ancestral and derived haplotypes.
Arthur Neuberger, Alexey Shalygin, Yury A Trofimov, Irina I Veretenenko, Kirill D Nadezhdin

Structure· January 2025

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Kainate receptor channel opening and gating mechanism.
Shanti Pal Gangwar, Maria V Yelshanskaya, Kirill D Nadezhdin, Laura Y Yen, Thomas P Newton

Nature· June 2024

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Dynamic molecular portraits of ion-conducting pores characterize functional states of TRPV channels.
Yury A Trofimov, Nikolay A Krylov, Alexander S Minakov, Kirill D Nadezhdin, Arthur Neuberger

Commun Chem· June 2024

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TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Kirill D Nadezhdin, Arthur Neuberger, Lena S Khosrof, Irina A Talyzina, Jeffrey Khau

Sci Adv· May 2024

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Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930.
Kirill D Nadezhdin, Leonor Correia, Alexey Shalygin, Muhammed Aktolun, Arthur Neuberger

Cell Rep· April 2024

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Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin.
Arthur Neuberger, Yury A Trofimov, Maria V Yelshanskaya, Jeffrey Khau, Kirill D Nadezhdin

Nat Commun· August 2023

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Structure of human TRPV4 in complex with GTPase RhoA.
Kirill D Nadezhdin, Irina A Talyzina, Aravind Parthasarathy, Arthur Neuberger, David X Zhang

Nat Commun· June 2023

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Structural mechanisms of TRPM7 activation and inhibition.
Kirill D Nadezhdin, Leonor Correia, Chamali Narangoda, Dhilon S Patel, Arthur Neuberger

Nat Commun· May 2023

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Human TRPV1 structure and inhibition by the analgesic SB-366791.
Arthur Neuberger, Mai Oda, Yury A Nikolaev, Kirill D Nadezhdin, Elena O Gracheva

Nat Commun· April 2023

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Structural snapshots of the mechanism of TRPV2 channel activation by small-molecule agonists.
Kirill D Nadezhdin, Arthur Neuberger, Alexander I Sobolevsky

Cell Calcium· July 2022

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Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine.
Arthur Neuberger, Kirill D Nadezhdin, Alexander I Sobolevsky

Nat Commun· May 2022

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Structural mechanism of TRPV3 channel inhibition by the plant-derived coumarin osthole.
Arthur Neuberger, Kirill D Nadezhdin, Eleonora Zakharian, Alexander I Sobolevsky

EMBO Rep· November 2021

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Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
Arthur Neuberger, Kirill D Nadezhdin, Alexander I Sobolevsky

Nat Commun· November 2021

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AlldEnantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-β Precursors.
Eduard V Bocharov, Lothar Gremer, Anatoly S Urban, Ivan S Okhrimenko, Pavel E Volynsky, Kirill D Nadezhdin

J Med Chem· November 2021

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Interaction between the transmembrane domains of neurotrophin receptors p75 and TrkA mediates their reciprocal activation.
María L Franco, Kirill D Nadezhdin, Taylor P Light, Sergey A Goncharuk, Andrea Soler-Lopez

J Biol Chem· August 2021

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Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Kirill D Nadezhdin, Arthur Neuberger, Yuri A Trofimov, Nikolay A Krylov, Viktor Sinica

Nat Struct Mol Biol· July 2021

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TRPV3 expression and purification for structure determination by Cryo-EM.
Arthur Neuberger, Kirill D Nadezhdin, Alexander I Sobolevsky

Methods Enzymol· June 2021

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Structure and function of the calcium-selective TRP channel TRPV6.
Maria V Yelshanskaya, Kirill D Nadezhdin, Maria G Kurnikova, Alexander I Sobolevsky

J Physiol· May 2021

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Extracellular cap domain is an essential component of the TRPV1 gating mechanism.
Kirill D Nadezhdin, Arthur Neuberger, Yury A Nikolaev, Lyle A Murphy, Elena O Gracheva

Nat Commun· April 2021

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Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Rajesh Bhardwaj, Sonja Lindinger, Arthur Neuberger, Kirill D Nadezhdin, Appu K Singh

Sci Adv· November 2020

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Revising the mechanism of p75NTR activation: intrinsically monomeric state of death domains invokes the "helper" hypothesis.
Sergey A Goncharuk, Lilya E Artemieva, Kirill D Nadezhdin, Alexander S Arseniev, Konstantin S Mineev

Sci Rep· August 2020

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Purification of native CCL7 and its functional interaction with selected chemokine receptors.
Marina V Goncharuk, Debarati Roy, Maxim A Dubinnyi, Kirill D Nadezhdin, Ashish Srivastava

Protein Expr Purif· July 2020

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Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor.
María L Franco, Kirill D Nadezhdin, Sergey A Goncharuk, Konstantin S Mineev, Alexander S Arseniev

J Biol Chem· January 2020

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