Publications by authors named "Kit I Tong"

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GNAS knockout potentiates HDAC3 inhibition through viral mimicry-related interferon responses in lymphoma.
Michael Y He, Kit I Tong, Ting Liu, Ryder Whittaker Hawkins, Victoria Shelton

Leukemia· October 2024

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Correction: Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development.
Masahito Kawazu, Kayoko Saso, Kit I Tong, Tracy McQuire, Kouichiro Goto

PLoS One· May 2024

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Association of C-reactive protein with future development of diabetes: a population-based 7-year cohort study among Norwegian adults aged 30 and older in the Tromsø Study 2007-2016.
Kit I Tong, Laila Arnesdatter Hopstock, Sarah Cook

BMJ Open· September 2023

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Combined EZH2 Inhibition and IKAROS Degradation Leads to Enhanced Antitumor Activity in Diffuse Large B-cell Lymphoma.
Kit I Tong, Sharon Yoon, Keren Isaev, Mehran Bakhtiari, Tracy Lackraj

Clin Cancer Res· October 2021

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The H3K27 demethylase, Utx, regulates adipogenesis in a differentiation stage-dependent manner.
Kazushige Ota, Kit I Tong, Kouichiro Goto, Shuta Tomida, Akiyoshi Komuro

PLoS One· August 2017

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Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model.
Kit I Tong, Kazushige Ota, Akiyoshi Komuro, Takeshi Ueda, Akihiko Ito

Cell Death Dis· October 2016

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Selective isotope labeling of recombinant proteins in Escherichia coli.
Kit I Tong, Masayuki Yamamoto, Toshiyuki Tanaka

Methods Mol Biol· November 2012

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Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism.
Emilia Kansanen, Gustavo Bonacci, Francisco J Schopfer, Suvi M Kuosmanen, Kit I Tong

J Biol Chem· April 2011

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Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.
Masahito Kawazu, Kayoko Saso, Kit I Tong, Tracy McQuire, Kouichiro Goto

PLoS One· March 2011

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The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response.
Shigemoto Fujii, Tomohiro Sawa, Hideshi Ihara, Kit I Tong, Tomoaki Ida

J Biol Chem· July 2010

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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Masaaki Komatsu, Hirofumi Kurokawa, Satoshi Waguri, Keiko Taguchi, Akira Kobayashi, Kit I Tong

Nat Cell Biol· March 2010

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Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains.
Toshihiko Ogura, Kit I Tong, Kazuhiro Mio, Yuusuke Maruyama, Hirofumi Kurokawa

Proc Natl Acad Sci U S A· February 2010

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Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.
Tatsuhiro Shibata, Tsutomu Ohta, Kit I Tong, Akiko Kokubu, Reiko Odogawa

Proc Natl Acad Sci U S A· September 2008

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A simple method for amino acid selective isotope labeling of recombinant proteins in E. coli.
Kit I Tong, Masayuki Yamamoto, Toshiyuki Tanaka

J Biomol NMR· September 2008

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Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap1.
Balasundaram Padmanabhan, Kit I Tong, Akira Kobayashi, Masayuki Yamamoto, Shigeyuki Yokoyama

J Synchrotron Radiat· May 2008

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Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.
Kit I Tong, Balasundaram Padmanabhan, Akira Kobayashi, Chengwei Shang, Yosuke Hirotsu

Mol Cell Biol· November 2007

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Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.
Takashi Toyama, Daigo Sumi, Yasuhiro Shinkai, Akira Yasutake, Keiko Taguchi, Kit I Tong

Biochem Biophys Res Commun· November 2007

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Crystallographic evidence for water-assisted photo-induced peptide cleavage in the stony coral fluorescent protein Kaede.
Ikuko Hayashi, Hideaki Mizuno, Kit I Tong, Toshiaki Furuta, Fujie Tanaka

J Mol Biol· September 2007

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Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.
Kit I Tong, Akira Kobayashi, Fumiki Katsuoka, Masayuki Yamamoto

Biol Chem· December 2006

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[Oxidative/electrophilic stress sensor Keap1 regulates the rapid turnover of transcripition factor Nrf2].
Akira Kobayashi, Kit I Tong

Tanpakushitsu Kakusan Koso· August 2006

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Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.
Kit I Tong, Yasutake Katoh, Hideki Kusunoki, Ken Itoh, Toshiyuki Tanaka

Mol Cell Biol· April 2006

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Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.
Balasundaram Padmanabhan, Kit I Tong, Tsutomu Ohta, Yoshihiro Nakamura, Maria Scharlock

Mol Cell· March 2006

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Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1.
Akira Kobayashi, Moon-Il Kang, Yoriko Watai, Kit I Tong, Takahiro Shibata

Mol Cell Biol· January 2006

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Mg2+ and Ca2+ differentially regulate DNA binding and dimerization of DREAM.
Masanori Osawa, Alexandra Dace, Kit I Tong, Aswani Valiveti, Mitsuhiko Ikura

J Biol Chem· May 2005

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Purification, crystallization and preliminary X-ray diffraction analysis of the Kelch-like motif region of mouse Keap1.
Balasundaram Padmanabhan, Maria Scharlock, Kit I Tong, Yoshihiro Nakamura, Moon-Il Kang

Acta Crystallogr Sect F Struct Biol Cryst Commun· January 2005

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