Publications by authors named "Knut Rennert"

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Modelling of the multicellular tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) on a fit-for-purpose biochip for preclinical drug discovery.
Alina Deipenbrock, Ben Eric Wilmes, Thomas Sommermann, Nader Abdo, Kyra Moustakas, Knut Rennert

Lab Chip· April 2025

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Immunocompetent Alveolus-on-Chip Model for Studying Alveolar Mucosal Immune Responses.
Hristina Koceva, Mona Amiratashani, Knut Rennert, Alexander S Mosig

J Vis Exp· May 2024

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Evaluation of drug-induced liver toxicity of trovafloxacin and levofloxacin in a human microphysiological liver model.
Tim Kaden, Katja Graf, Knut Rennert, Ruoya Li, Alexander S Mosig

Sci Rep· August 2023

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Generation & characterization of expandable human liver sinusoidal endothelial cells and their application to assess hepatotoxicity in an advanced in vitro liver model.
Tim Kaden, Astrid Noerenberg, Jennifer Boldt, Carolin Sagawe, Timo Johannssen, Knut Rennert

Toxicology· January 2023

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Lung Infection Results in Down-Regulation of Surfactant Protein-A Mainly Caused by Pro-Inflammatory Macrophages.
Elisabeth Schicke, Zoltán Cseresnyés, Knut Rennert, Vanessa Vau, Karoline Frieda Haupt

Microorganisms· April 2020

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The Peroxisome Proliferator-Activated Receptor (PPAR)- Antagonist 2-Chloro-5-Nitro-N-Phenylbenzamide (GW9662) Triggers Perilipin 2 Expression via PPAR and Induces Lipogenesis and Triglyceride Accumulation in Human THP-1 Macrophages.
Martin Schubert, Stefanie Becher, Maria Wallert, Marten B Maeß, Masoumeh Abhari, Knut Rennert

Mol Pharmacol· March 2020

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Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model.
Stefanie Deinhardt-Emmer, Knut Rennert, Elisabeth Schicke, Zoltán Cseresnyés, Maximilian Windolph

Biofabrication· February 2020

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Corrigendum: Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.
Marko Gröger, Knut Rennert, Benjamin Giszas, Elisabeth Weiß, Julia Dinger

Sci Rep· May 2018

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Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance.
Anika Mann, Thomas Pelz, Knut Rennert, Alexander Mosig, Michael Decker

Hum Cell· October 2017

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Thermo-responsive cell culture carrier: Effects on macrophage functionality and detachment efficiency.
Knut Rennert, Mirko Nitschke, Maria Wallert, Natalie Keune, Martin Raasch

J Tissue Eng· August 2017

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Novel approach for the prediction of cell densities and viability in standardized translucent cell culture biochips with near infrared spectroscopy.
Marko Gröger, Matthias Lange, Knut Rennert, Tobias Kaschowitz, Holger Plettenberg

Eng Life Sci· May 2017

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Recruitment of CD16(+) monocytes to endothelial cells in response to LPS-treatment and concomitant TNF release is regulated by CX3CR1 and interfered by soluble fractalkine.
Knut Rennert, Kerstin Heisig, Marko Groeger, Maria Wallert, Harald Funke

Cytokine· July 2016

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An integrative microfluidically supported in vitro model of an endothelial barrier combined with cortical spheroids simulates effects of neuroinflammation in neocortex development.
Martin Raasch, Knut Rennert, Tobias Jahn, Claudia Gärtner, Gilbert Schönfelder

Biomicrofluidics· July 2016

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Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.
Marko Gröger, Knut Rennert, Benjamin Giszas, Elisabeth Weiß, Julia Dinger

Sci Rep· February 2016

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A human macrophage-hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica.
Knut Rennert, Peter Otto, Harald Funke, Otmar Huber, Herbert Tomaso

BMC Microbiol· January 2016

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A microfluidically perfused three dimensional human liver model.
Knut Rennert, Sandra Steinborn, Marko Gröger, Birgit Ungerböck, Anne-Marie Jank

Biomaterials· December 2015

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Optimization of the transfection of human THP-1 macrophages by application of Nunc UpCell technology.
Marten B Maeß, Andrea-Anneliese Keller, Knut Rennert, Alexander Mosig, Stefan Lorkowski

Anal Biochem· June 2015

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Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions.
Martin Raasch, Knut Rennert, Tobias Jahn, Sven Peters, Thomas Henkel

Biofabrication· March 2015

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Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro.
Maria Wallert, Sandy Mosig, Knut Rennert, Harald Funke, Michael Ristow

Free Radic Biol Med· March 2014

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Different functions of monocyte subsets in familial hypercholesterolemia: potential function of CD14+ CD16+ monocytes in detoxification of oxidized LDL.
Sandy Mosig, Knut Rennert, Siegfried Krause, Julia Kzhyshkowska, Kerstin Neunübel

FASEB J· March 2009

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Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism.
Sandy Mosig, Knut Rennert, Petra Büttner, Siegfried Krause, Dieter Lütjohann

BMC Med Genomics· November 2008

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Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells.
Ignacio Rubio, Knut Rennert, Ute Wittig, Katrin Beer, Matthias Dürst

Biochem J· September 2006

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Live-cell imaging of endogenous Ras-GTP illustrates predominant Ras activation at the plasma membrane.
Martin Augsten, Rico Pusch, Christoph Biskup, Knut Rennert, Ute Wittig

EMBO Rep· January 2006

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Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor.
Ignacio Rubio, Knut Rennert, Ute Wittig, Reinhard Wetzker

Biochem J· December 2003

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