Publications by authors named "Knut Woltjen"

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Efficient generation of single copy transgenic mice using piggyBat transposase from the little brown bat Myotis lucifugus†.
Eiichi Okamura, Shoma Matsumoto, Hayate Suzuki, Yoko Tanimoto, Tra Thi Huong Dinh, Knut Woltjen

Biol Reprod· October 2025

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Characterizing primary and secondary senescence in vivo.
Yuko Sogabe, Hirofumi Shibata, Mio Kabata, Akito Tanaka, Kanae Mitsunaga, Knut Woltjen

Nat Aging· August 2025

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Skin health and biological aging.
David Furman, Johan Auwerx, Anne-Laure Bulteau, George Church, Virginie Couturaud, Knut Woltjen

Nat Aging· July 2025

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Diversifying the reference iPSC line concept.
James Ellis, Knut Woltjen, Seema Mital, Megumu K Saito, Akitsu Hotta

Cell Stem Cell· June 2025

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Efficient differentiation of human iPSCs into Leydig-like cells capable of long-term stable secretion of testosterone.
Katsuya Sato, Michiyo Koyanagi-Aoi, Keiichiro Uehara, Yosuke Yamashita, Masakazu Shinohara, Knut Woltjen

Stem Cell Reports· February 2025

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Enrichment of Allelic Editing Outcomes by Prime Editing in Induced Pluripotent Stem Cells.
Ryo Niwa, Tomoko Matsumoto, Alexander Y Liu, Maki Kawato, Takayuki Kondo, Knut Woltjen

CRISPR J· October 2024

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Corrigendum: ACE2 knockout hinders SARS-CoV-2 propagation in iPS cell-derived airway and alveolar epithelial cells.
Ryo Niwa, Kouji Sakai, Mandy Siu Yu Lung, Tomoko Matsumoto, Ryuta Mikawa, Knut Woltjen

Front Cell Dev Biol· June 2024

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Hypoblast from human pluripotent stem cells regulates epiblast development.
Takumi Okubo, Nicolas Rivron, Mio Kabata, Hideki Masaki, Keiko Kishimoto, Knut Woltjen

Nature· February 2024

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Publisher Correction: Hypoblast from human pluripotent stem cells regulates epiblast development.
Takumi Okubo, Nicolas Rivron, Mio Kabata, Hideki Masaki, Keiko Kishimoto, Knut Woltjen

Nature· February 2024

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Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues.
Thomas L Maurissen, Masahide Kawatou, Víctor López-Dávila, Kenji Minatoya, Jun K Yamashita, Knut Woltjen

Sci Rep· January 2024

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ACE2 knockout hinders SARS-CoV-2 propagation in iPS cell-derived airway and alveolar epithelial cells.
Ryo Niwa, Kouji Sakai, Mandy Siu Yu Lung, Tomoko Matsumoto, Ryuta Mikawa, Knut Woltjen

Front Cell Dev Biol· December 2023

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mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells.
Musashi Kubiura-Ichimaru, Christopher Penfold, Kazuaki Kojima, Constance Dollet, Haruka Yabukami, Knut Woltjen

Stem Cell Reports· October 2023

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Uniform transgene activation in Tet-On systems depends on sustained rtTA expression.
Jun Otomo, Knut Woltjen, Hidetoshi Sakurai

iScience· October 2023

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A disease-specific iPS cell resource for studying rare and intractable diseases.
Megumu K Saito, Mitsujiro Osawa, Nao Tsuchida, Kotaro Shiraishi, Akira Niwa, Knut Woltjen

Inflamm Regen· September 2023

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Programmable mammalian translational modulators by CRISPR-associated proteins.
Shunsuke Kawasaki, Hiroki Ono, Moe Hirosawa, Takeru Kuwabara, Shunsuke Sumi, Knut Woltjen

Nat Commun· April 2023

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Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Jingshan Gao, Takeru Makiyama, Yuta Yamamoto, Takuya Kobayashi, Hisaaki Aoki, Knut Woltjen

Circ Arrhythm Electrophysiol· March 2023

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Disrupted Ca1.2 selectivity causes overlapping long QT and Brugada syndrome phenotypes in the CACNA1C-E1115K iPS cell model.
Asami Kashiwa, Takeru Makiyama, Hirohiko Kohjitani, Thomas L Maurissen, Taisuke Ishikawa, Knut Woltjen

Heart Rhythm· January 2023

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Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells.
Tatsuki Ueda, Sara Shiina, Shoichi Iriguchi, Seitaro Terakura, Yohei Kawai, Knut Woltjen

Nat Biomed Eng· January 2023

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Differentiation of pluripotent stem cells for modeling human skin development and potential applications.
Fabian Oceguera-Yanez, Alfonso Avila-Robinson, Knut Woltjen

Front Cell Dev Biol· November 2022

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The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
Kenji Ito, Kohei Nagata, Sho Ohta, Yutaka Matsuda, Tomoyo Ukai, Knut Woltjen

Cell Rep· April 2022

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A stress-reduced passaging technique improves the viability of human pluripotent cells.
Kazutoshi Takahashi, Chikako Okubo, Michiko Nakamura, Mio Iwasaki, Yuka Kawahara, Knut Woltjen

Cell Rep Methods· February 2022

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DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency.
Jumpei Taguchi, Hirofumi Shibata, Mio Kabata, Masaki Kato, Kei Fukuda, Knut Woltjen

Nat Commun· August 2021

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Capturing human trophoblast development with naive pluripotent stem cells in vitro.
Shingo Io, Mio Kabata, Yoshiki Iemura, Katsunori Semi, Nobuhiro Morone, Knut Woltjen

Cell Stem Cell· June 2021

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Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice.
Nao Sankoda, Wataru Tanabe, Akito Tanaka, Hirofumi Shibata, Knut Woltjen

Nat Commun· January 2021

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Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation.
Thomas L Maurissen, Knut Woltjen

Nat Commun· June 2020

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