Publications by authors named "Koen D Flach"

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A 3D genome compendium of breast cancer progression.
Teun van den Brand, Maria Donaldson Collier, Koen D Flach, Sebastian Gregoricchio, Isabel Mayayo-Peralta

iScience· September 2025

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Distinct roles for CKM-Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction.
Emilia Dimitrova, Angelika Feldmann, Robin H van der Weide, Koen D Flach, Anna Lastuvkova

Nat Struct Mol Biol· October 2022

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A Mediator-cohesin axis controls heterochromatin domain formation.
Judith H I Haarhuis, Robin H van der Weide, Vincent A Blomen, Koen D Flach, Hans Teunissen

Nat Commun· February 2022

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Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer.
Koen D Flach, Manikandan Periyasamy, Ajit Jadhav, Dorjbal Dorjsuren, Joseph C Siefert

Cancer Res· May 2020

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Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)-PathIES.
Zsolt Szijgyarto, Koen D Flach, Mark Opdam, Carlo Palmieri, Sabine C Linn

Breast Cancer Res Treat· May 2019

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Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas.
Marjolein Droog, Ekaterina Nevedomskaya, Yongsoo Kim, Tesa Severson, Koen D Flach

Cancer Res· July 2016

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The first decade of estrogen receptor cistromics in breast cancer.
Koen D Flach, Wilbert Zwart

J Endocrinol· May 2016

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SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer.
Wilbert Zwart, Koen D Flach, Bharath Rudraraju, Tarek M A Abdel-Fatah, Ondrej Gojis

Clin Cancer Res· January 2016

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Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.
Chun-Fui Lai, Koen D Flach, Xanthippi Alexi, Stephen P Fox, Silvia Ottaviani

Nucleic Acids Res· December 2013

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Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
Ingrid J De Vries-van Leeuwen, Daniel da Costa Pereira, Koen D Flach, Sander R Piersma, Christian Haase

Proc Natl Acad Sci U S A· May 2013

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