Publications by authors named "Koen Mertens"

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Probing activation-driven changes in coagulation factor IX by mass spectrometry.
Nadia Freato, Floris P J van Alphen, Mariëtte Boon-Spijker, Maartje van den Biggelaar, Alexander B Meijer, Koen Mertens

J Thromb Haemost· June 2021

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Factor VIII-driven changes in activated factor IX explored by hydrogen-deuterium exchange mass spectrometry.
Nadia Freato, Eduard H T M Ebberink, Josse van Galen, Caroline Fribourg, Mariëtte Boon-Spijker, Koen Mertens

Blood· December 2020

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D' domain region Arg782-Cys799 of von Willebrand factor contributes to factor VIII binding.
Małgorzata A Przeradzka, Josse van Galen, Eduard H T M Ebberink, Arie J Hoogendijk, Carmen van der Zwaan, Koen Mertens

Haematologica· June 2020

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Endocytosis by macrophages: interplay of macrophage scavenger receptor-1 and LDL receptor-related protein-1.
Eelke P Béguin, Małgorzata A Przeradzka, Esmée F J Janssen, Henriët Meems, Magdalena Sedek, Koen Mertens

Haematologica· March 2020

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Unique surface-exposed hydrophobic residues in the C1 domain of factor VIII contribute to cofactor function and von Willebrand factor binding.
Małgorzata A Przeradzka, Nadia Freato, Mariëtte Boon-Spijker, Josse van Galen, Carmen van der Zwaan, Koen Mertens

J Thromb Haemost· February 2020

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Integrated proteomic analysis of tumor necrosis factor α and interleukin 1β-induced endothelial inflammation.
Eelke P Béguin, Bart L van den Eshof, Arie J Hoogendijk, Benjamin Nota, Koen Mertens

J Proteomics· February 2019

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The D' domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding.
Małgorzata A Przeradzka, Henriet Meems, Carmen van der Zwaan, Eduard H T M Ebberink, Maartje van den Biggelaar, Koen Mertens

Biochem J· September 2018

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Paradigm of Biased PAR1 (Protease-Activated Receptor-1) Activation and Inhibition in Endothelial Cells Dissected by Phosphoproteomics.
Bart L van den Eshof, Arie J Hoogendijk, Pelle J Simpson, Floris P J van Alphen, Sara Zanivan, Koen Mertens

Arterioscler Thromb Vasc Biol· October 2017

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Differences between Platelets Derived from Neonatal Cord Blood and Adult Peripheral Blood Assessed by Mass Spectrometry.
Eva Stokhuijzen, Johanna Maria Koornneef, Benjamin Nota, Bart Laurens van den Eshof, Floris Pieter Joachim van Alphen, Koen Mertens

J Proteome Res· October 2017

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Cellular uptake of coagulation factor VIII: Elusive role of the membrane-binding spikes in the C1 domain.
Lydia Castro-Núñez, Johanna M Koornneef, Mariska G Rondaij, Esther Bloem, Carmen van der Zwaan, Koen Mertens

Int J Biochem Cell Biol· August 2017

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Whole-exome sequencing in evaluation of patients with venous thromboembolism.
Eun-Ju Lee, Daniel J Dykas, Andrew D Leavitt, Rodney M Camire, Eduard Ebberink, Koen Mertens

Blood Adv· July 2017

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Development of a Stereovision-Based Technique to Measure the Spread Patterns of Granular Fertilizer Spreaders.
Simon R Cool, Jan G Pieters, Dejan Seatovic, Koen C Mertens, David Nuyttens

Sensors (Basel)· June 2017

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Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking.
Eduard H T M Ebberink, Eveline A M Bouwens, Esther Bloem, Mariëtte Boon-Spijker, Maartje van den Biggelaar, Koen Mertens

Haematologica· April 2017

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Role of glycine 221 in catalytic activity of hyaluronan-binding protein 2.
Fabian Stavenuiter, Eduard H T M Ebberink, Koen Mertens, Alexander B Meijer

J Biol Chem· April 2017

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Recombinant Expression of the Full-length Ectodomain of LDL Receptor-related Protein 1 (LRP1) Unravels pH-dependent Conformational Changes and the Stoichiometry of Binding with Receptor-associated Protein (RAP).
Camilla De Nardis, Philip Lössl, Maartje van den Biggelaar, Pramod K Madoori, Nadia Leloup, Koen Mertens

J Biol Chem· January 2017

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Development of a High Irradiance LED Configuration for Small Field of View Motion Estimation of Fertilizer Particles.
Simon Cool, Jan G Pieters, Koen C Mertens, Sergio Mora, Frédéric Cointault

Sensors (Basel)· November 2015

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Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising "Hot-Spot" Lysine Residues.
Maartje van den Biggelaar, Jesper J Madsen, Johan H Faber, Marleen G Zuurveld, Carmen van der Zwaan, Koen Mertens

J Biol Chem· July 2015

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A novel chemical footprinting approach identifies critical lysine residues involved in the binding of receptor-associated protein to cluster II of LDL receptor-related protein.
Esther Bloem, Eduard H T M Ebberink, Maartje van den Biggelaar, Carmen van der Zwaan, Koen Mertens

Biochem J· May 2015

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High speed stereovision setup for position and motion estimation of fertilizer particles leaving a centrifugal spreader.
Bilal Hijazi, Simon Cool, Jürgen Vangeyte, Koen C Mertens, Frédéric Cointault

Sensors (Basel)· November 2014

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Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells.
Maartje van den Biggelaar, Juan Ramon Hernández-Fernaud, Bart L van den Eshof, Lisa J Neilson, Alexander B Meijer, Koen Mertens

Blood· March 2014

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The effect of shiga toxin on weibel-palade bodies in primary human endothelial cells.
Joyce Geelen, Maartje van den Biggelaar, Peter Linssen, Thea van der Velden, Koen Mertens

Nephron Extra· January 2014

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Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake.
Esther Bloem, Maartje van den Biggelaar, Aleksandra Wroblewska, Jan Voorberg, Johan H Faber, Koen Mertens

J Biol Chem· October 2013

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A3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IX.
Esther Bloem, Henriet Meems, Maartje van den Biggelaar, Koen Mertens, Alexander B Meijer

J Biol Chem· September 2013

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Validation of 18F-FDG PET at conventional and delayed intervals for the discrimination of high-grade from low-grade gliomas: a stereotactic PET and MRI study.
Koen Mertens, Marjan Acou, Jel Van Hauwe, Ine De Ruyck, Caroline Van den Broecke

Clin Nucl Med· July 2013

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Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.
Jiong-Wei Wang, Eveline A M Bouwens, Maria Carolina Pintao, Jan Voorberg, Huma Safdar, Koen Mertens

Blood· April 2013

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