Publications by authors named "Koen Sedeyn"

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Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base.
Sieglinde De Cae, Inge Van Molle, Loes van Schie, Sophie R Shoemaker, Julie Deckers, Koen Sedeyn

Nat Commun· May 2025

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Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa.
Jozefien Declercq, Sarah Gerlo, Sharon Van Nevel, Natalie De Ruyck, Gabriele Holtappels, Koen Sedeyn

Sci Transl Med· October 2024

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Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted.
Delphine Diana Acar, Wojciech Witkowski, Magdalena Wejda, Ruifang Wei, Tim Desmet, Koen Sedeyn

EBioMedicine· February 2024

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Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins.
Livija Tušar, Jure Loboda, Francis Impens, Piotr Sosnowski, Emmy Van Quickelberghe, Koen Sedeyn

Commun Biol· April 2023

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An Unexpected Encounter: Respiratory Syncytial Virus Nonstructural Protein 1 Interacts with Mediator Subunit MED25.
Tessa Van Royen, Koen Sedeyn, George D Moschonas, Wendy Toussaint, Marnik Vuylsteke

J Virol· October 2022

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How RSV Proteins Join Forces to Overcome the Host Innate Immune Response.
Tessa Van Royen, Iebe Rossey, Koen Sedeyn, Bert Schepens, Xavier Saelens

Viruses· February 2022

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An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.
Bert Schepens, Loes van Schie, Wim Nerinckx, Kenny Roose, Wander Van Breedam, Koen Sedeyn

Sci Transl Med· November 2021

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Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.
Fabien Thery, Lia Martina, Caroline Asselman, Yifeng Zhang, Madeleine Vessely, Koen Sedeyn

Nat Commun· October 2021

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Protective Efficacy of Recombinant Influenza Hemagglutinin Ectodomain Fusions.
Nidhi Mittal, Nayanika Sengupta, Sameer Kumar Malladi, Poorvi Reddy, Madhuraj Bhat, Koen Sedeyn

Viruses· August 2021

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A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
Iebe Rossey, Ching-Lin Hsieh, Koen Sedeyn, Marlies Ballegeer, Bert Schepens

J Virol· May 2021

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New antibody-based prevention and treatment options for influenza.
Koen Sedeyn, Xavier Saelens

Antiviral Res· October 2019

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Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses.
Koen Sedeyn, Bert Schepens, Xavier Saelens

PLoS Pathog· October 2019

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Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Iebe Rossey, Morgan S A Gilman, Stephanie C Kabeche, Koen Sedeyn, Daniel Wrapp

Nat Commun· November 2017

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Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Iebe Rossey, Morgan S A Gilman, Stephanie C Kabeche, Koen Sedeyn, Daniel Wrapp

Nat Commun· February 2017

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Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein.
Bert Schepens, Koen Sedeyn, Liesbeth Vande Ginste, Sarah De Baets, Michael Schotsaert

EMBO Mol Med· November 2014

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CD8+ T cell immunity against human respiratory syncytial virus.
Iebe Rossey, Koen Sedeyn, Sarah De Baets, Bert Schepens, Xavier Saelens

Vaccine· October 2014

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Recombinant influenza virus carrying the respiratory syncytial virus (RSV) F85-93 CTL epitope reduces RSV replication in mice.
Sarah De Baets, Bert Schepens, Koen Sedeyn, Michael Schotsaert, Kenny Roose

J Virol· March 2013

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