Publications by authors named "Koit Aasumets"

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MRE11-independent effects of Mirin on mitochondrial DNA integrity and cellular immune responses.
Koit Aasumets, Anu Hangas, Georgios Fragkoulis, Cyrielle P J Bader, Direnis Erdinc

Mol Biol Cell· February 2025

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Species-specific variation in mitochondrial genome tandem repeat polymorphisms in hares (Lepus spp., Lagomorpha, Leporidae) provides insight into their evolution.
Riikka Tapanainen, Koit Aasumets, Zsófia Fekete, Steffi Goffart, Eric Dufour

Gene· October 2024

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Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells.
Mara Doimo, Namrata Chaudhari, Sanna Abrahamsson, Valentin L'Hôte, Tran V H Nguyen, Koit Aasumets

Nucleic Acids Res· August 2023

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TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane contacts.
Koit Aasumets, Yuliya Basikhina, Jaakko L Pohjoismäki, Steffi Goffart, Joachim Gerhold

Biochem Biophys Rep· December 2021

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Chemical, Physical and Biological Triggers of Evolutionary Conserved Bcl-xL-Mediated Apoptosis.
Aleksandr Ianevski, Evgeny Kulesskiy, Klara Krpina, Guofeng Lou, Yahyah Aman, Koit Aasumets

Cancers (Basel)· June 2020

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Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and .
Anita Wagner, Olga Hofmeister, Stephane G Rolland, Andreas Maiser, Koit Aasumets

J Cell Sci· October 2019

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Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2.
Anu Hangas, Koit Aasumets, Nina J Kekäläinen, Mika Paloheinä, Jaakko L Pohjoismäki

Nucleic Acids Res· October 2018

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