Publications by authors named "Konrad Talbot"

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Basic Science and Pathogenesis.
Xuelin Gu, Tim Distel, Konrad Talbot

Alzheimers Dement· December 2025

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Impact of cardiometabolic conditions on the progression from mild cognitive impairment to dementia: A large cohort study.
Filippos Anagnostakis, Michail Kokkorakis, Christos Asvestis, Ilias Papadimopoulos, Shrihari Nagarajan, Konrad Talbot

Alzheimers Dement· September 2025

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Brain uptake pharmacokinetics of albiglutide, dulaglutide, tirzepatide, and DA5-CH in the search for new treatments of Alzheimer's and Parkinson's diseases.
Elizabeth M Rhea, Alice Babin, Peter Thomas, Mohamed Omer, Riley Weaver, Konrad Talbot

Tissue Barriers· October 2024

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Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer's disease.
Noor Abdulhameed, Alice Babin, Kim Hansen, Riley Weaver, William A Banks, Konrad Talbot

Alzheimers Res Ther· August 2024

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Editorial Expression of Concern: Altered neuregulin 1-erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia.
Chang-Gyu Hahn, Hoau-Yan Wang, Dan-Sung Cho, Konrad Talbot, Raquel E Gur

Nat Med· March 2024

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Corrigendum to "Brain uptake pharmacokinetics of incretin receptor agonists showing promise as Alzheimer's and Parkinson's disease therapeutics" [Biochem. Pharmacol. 180 (2020) 114187].
Therese S Salameh, Elizabeth M Rhea, Konrad Talbot, William A Banks

Biochem Pharmacol· April 2023

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Brain energy failure in dementia syndromes: Opportunities and challenges for glucagon-like peptide-1 receptor agonists.
Hussein N Yassine, Victoria Solomon, Angad Thakral, Nasim Sheikh-Bahaei, Helena C Chui, Konrad Talbot

Alzheimers Dement· March 2022

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Brain uptake pharmacokinetics of incretin receptor agonists showing promise as Alzheimer's and Parkinson's disease therapeutics.
Therese S Salameh, Elizabeth M Rhea, Konrad Talbot, William A Banks

Biochem Pharmacol· October 2020

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Effects of Lifestyle Factors on Cognitive Resilience: Commentary on "What This Sunny, Religious Town in California Teaches Us About Living Longer".
Prativa Sherchan, Fayth Miles, Michael Orlich, Gary Fraser, John H Zhang, Konrad Talbot

Transl Stroke Res· April 2020

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Insulin resistance and cognitive test performance in elderly adults: National health and nutrition examination survey (NHANES).
Ayesha Z Sherzai, Magda Shaheen, Jeffrey J Yu, Konrad Talbot, Dean Sherzai

J Neurol Sci· May 2018

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Dysregulation of Specialized Delay/Interference-Dependent Working Memory Following Loss of Dysbindin-1A in Schizophrenia-Related Phenotypes.
Emilie I Petit, Zuzanna Michalak, Rachel Cox, Colm M P O'Tuathaigh, Niamh Clarke, Konrad Talbot

Neuropsychopharmacology· May 2017

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Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice-Potential Link to Cognitive Impairment in Schizophrenia.
Yong Chen, Sookhee Bang, Mary F McMullen, Hala Kazi, Konrad Talbot

Mol Neurobiol· April 2017

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Novel GLP-1R/GIPR co-agonist "twincretin" is neuroprotective in cell and rodent models of mild traumatic brain injury.
Ian A Tamargo, Miaad Bader, Yazhou Li, Seong-Jin Yu, Yun Wang, Konrad Talbot

Exp Neurol· February 2017

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Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Menachem Fromer, Panos Roussos, Solveig K Sieberts, Jessica S Johnson, David H Kavanagh, Konrad Talbot

Nat Neurosci· November 2016

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Oxidative stress reduces levels of dysbindin-1A via its PEST domain.
Mei-Yi Alicia Yap, Yew-Long Lo, Konrad Talbot, Wei-Yi Ong

Neurochem Int· December 2014

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Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs.
Konrad Talbot

Neurodegener Dis Manag· November 2014

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MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons.
Jennifer Larimore, Pearl V Ryder, Kun-Yong Kim, L Alex Ambrose, Christopher Chapleau, Konrad Talbot

PLoS One· September 2014

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Newly identified precipitating factors in mechanical ventilation-induced brain damage: implications for treating ICU delirium.
Adrián González-López, Guillermo M Albaiceta, Konrad Talbot

Expert Rev Neurother· June 2014

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Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes.
Jennifer Larimore, Stephanie A Zlatic, Avanti Gokhale, Karine Tornieri, Kaela S Singleton, Konrad Talbot

J Biol Chem· May 2014

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Dysbindin-1 loss compromises NMDAR-dependent synaptic plasticity and contextual fear conditioning.
W Bailey Glen, Bryant Horowitz, Gregory C Carlson, Tyrone D Cannon, Konrad Talbot

Hippocampus· February 2014

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The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease.
Konrad Talbot, Hoau-Yan Wang

Alzheimers Dement· February 2014

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Mechanical ventilation triggers hippocampal apoptosis by vagal and dopaminergic pathways.
Adrián González-López, Inés López-Alonso, Alina Aguirre, Laura Amado-Rodríguez, Estefanía Batalla-Solís, Konrad Talbot

Am J Respir Crit Care Med· September 2013

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Measuring cell-type specific differential methylation in human brain tissue.
Carolina M Montaño, Rafael A Irizarry, Walter E Kaufmann, Konrad Talbot, Raquel E Gur

Genome Biol· August 2013

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An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.
Theresa R Bomfim, Leticia Forny-Germano, Luciana B Sathler, Jordano Brito-Moreira, Jean-Christophe Houzel, Konrad Talbot

J Clin Invest· April 2012

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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
Konrad Talbot, Hoau-Yan Wang, Hala Kazi, Li-Ying Han, Kalindi P Bakshi

J Clin Invest· April 2012

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