Publications by authors named "Kozo Ochi"

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Mutations within gene XNR_2147 for TetR-like protein enhance lincomycin resistance and endogenous specialized metabolism of Streptomyces albus J1074.
Vasylyna-Marta Tseduliak, Borys Dolia, Iryna Ostash, Maria Lopatniuk, Tobias Busche, Kozo Ochi

J Appl Genet· February 2023

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Multiple mutations in RNA polymerase β-subunit gene (rpoB) in Streptomyces incarnatus NRRL8089 enhance production of antiviral antibiotic sinefungin: modeling rif cluster region by density functional theory.
Saori Ogawa, Hitomi Shimidzu, Koji Fukuda, Naoki Tsunekawa, Toshiyuki Hirano, Kozo Ochi

Biosci Biotechnol Biochem· April 2021

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Genetically engineered rpsL merodiploidy impacts secondary metabolism and antibiotic resistance in Streptomyces.
Oksana Koshla, Maria Lopatniuk, Oksana Borys, Yuya Misaki, Volodymyr Kravets, Kozo Ochi

World J Microbiol Biotechnol· March 2021

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Substantial improvement of tetraene macrolide production in Streptomyces diastatochromogenes by cumulative drug resistance mutations.
Jing-Xuan Fan, Yang Song, Gu Tang, Kozo Ochi, Xu-Ping Shentu

PLoS One· July 2020

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A putative mechanism underlying secondary metabolite overproduction by Streptomyces strains with a 23S rRNA mutation conferring erythromycin resistance.
Kanata Hoshino, Yu Imai, Keiichiro Mukai, Ryoko Hamauzu, Kozo Ochi

Appl Microbiol Biotechnol· March 2020

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Substantial improvement of toyocamycin production in Streptomyces diastatochromogenes by cumulative drug-resistance mutations.
Xu-Ping Shentu, Zhen-Yan Cao, Yin Xiao, Gu Tang, Kozo Ochi

PLoS One· February 2019

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Combined Drug Resistance Mutations Substantially Enhance Enzyme Production in Paenibacillus agaridevorans.
Kazumi Funane, Yukinori Tanaka, Takeshi Hosaka, Kiriko Murakami, Takatsugu Miyazaki, Kozo Ochi

J Bacteriol· September 2018

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A possible mechanism for lincomycin induction of secondary metabolism in Streptomyces coelicolor A3(2).
Misaki Ishizuka, Yu Imai, Keiichiro Mukai, Kazuma Shimono, Ryoko Hamauzu, Kozo Ochi

Antonie Van Leeuwenhoek· May 2018

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Tri11, tri3, and tri4 genes are required for trichodermin biosynthesis of Trichoderma brevicompactum.
Xuping Shentu, Jiayi Yao, Xiaofeng Yuan, Linmao He, Fan Sun, Kozo Ochi

AMB Express· April 2018

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Enhancement of butanol production by sequential introduction of mutations conferring butanol tolerance and streptomycin resistance.
Yukinori Tanaka, Ken Kasahara, Yutaka Hirose, Yu Morimoto, Masumi Izawa, Kozo Ochi

J Biosci Bioeng· October 2017

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Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii.
Yukinori Tanaka, Ken Kasahara, Masumi Izawa, Kozo Ochi

Biosci Biotechnol Biochem· August 2017

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Metabolic perturbation to enhance polyketide and nonribosomal peptide antibiotic production using triclosan and ribosome-targeting drugs.
Yukinori Tanaka, Masumi Izawa, Yoshikazu Hiraga, Yuya Misaki, Tomoko Watanabe, Kozo Ochi

Appl Microbiol Biotechnol· June 2017

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Identification of a Novel Lincomycin Resistance Mutation Associated with Activation of Antibiotic Production in Streptomyces coelicolor A3(2).
Guojun Wang, Masumi Izawa, Xiaoge Yang, Dongbo Xu, Yukinori Tanaka, Kozo Ochi

Antimicrob Agents Chemother· February 2017

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Enhanced alcohol-drinking behavior associated with active ghrelinergic and serotoninergic neurons in the lateral hypothalamus and amygdala.
Kanji Yoshimoto, Masataka Nagao, Yoshihisa Watanabe, Takashi Yamaguchi, Shuichi Ueda, Kozo Ochi

Pharmacol Biochem Behav· February 2017

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Insights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects.
Kozo Ochi

J Antibiot (Tokyo)· January 2017

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Improved antibiotic production and silent gene activation in Streptomyces diastatochromogenes by ribosome engineering.
Xuping Shentu, Nannan Liu, Gu Tang, Yukinori Tanaka, Kozo Ochi

J Antibiot (Tokyo)· May 2016

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Activation of Antibiotic Production in Bacillus spp. by Cumulative Drug Resistance Mutations.
Shigeo Tojo, Yukinori Tanaka, Kozo Ochi

Antimicrob Agents Chemother· December 2015

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Overexpression of RelA/SpoT homologs, PpRSH2a and PpRSH2b, induces the growth suppression of the moss Physcomitrella patens.
Michio Sato, Tomohiro Takahashi, Kozo Ochi, Hideyuki Matsuura, Kensuke Nabeta

Biosci Biotechnol Biochem· October 2015

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Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.
Yu Imai, Seizo Sato, Yukinori Tanaka, Kozo Ochi, Takeshi Hosaka

Appl Environ Microbiol· June 2015

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The mthA mutation conferring low-level resistance to streptomycin enhances antibiotic production in Bacillus subtilis by increasing the S-adenosylmethionine pool size.
Shigeo Tojo, Ji-Yun Kim, Yukinori Tanaka, Takashi Inaoka, Yoshikazu Hiraga, Kozo Ochi

J Bacteriol· April 2014

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Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements.
Kozo Ochi, Yukinori Tanaka, Shigeo Tojo

J Ind Microbiol Biotechnol· February 2014

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Chromosomal circularization of the model Streptomyces species, Streptomyces coelicolor A3(2).
Yosi Nindita, Tomoya Nishikawa, Kenji Arakawa, Guojun Wang, Kozo Ochi

FEMS Microbiol Lett· October 2013

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Activation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes.
Yukinori Tanaka, Ken Kasahara, Yutaka Hirose, Kiriko Murakami, Rie Kugimiya, Kozo Ochi

J Bacteriol· July 2013

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Structure and biosynthesis of scabichelin, a novel tris-hydroxamate siderophore produced by the plant pathogen Streptomyces scabies 87.22.
Shinya Kodani, Joanna Bicz, Lijiang Song, Robert J Deeth, Mayumi Ohnishi-Kameyama, Kozo Ochi

Org Biomol Chem· July 2013

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rRNA (rrn) operon-engineered Bacillus subtilis as a feasible test organism for antibiotic discovery.
Yukinori Tanaka, Hideaki Nanamiya, Koichi Yano, Koji Kakugawa, Fujio Kawamura, Kozo Ochi

Antimicrob Agents Chemother· April 2013

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