Publications by authors named "Krishnakumar Im"

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Quercetin hybrid-hydrogel microparticles modulate gut microbiota and improve memory in an antibiotic-induced dysbiosis rat model.
Sherin Joy Parappilly, Deepa Azhchath Vasu, K A Athira Krishnan, M B Yadukrishnan, Mohind C Mohan

Sci Rep· November 2025

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Co-delivery of curcumin-resveratrol-carnosic acid complex promotes neurogenesis and cognitive recovery in a rodent model of repeated mild traumatic brain injury.
Mohind C Mohan, A S Anjana, T A Hilmi Jaufer, Ayswaria Deepti, I M Krishnakumar

Biomed Pharmacother· February 2025

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Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study.
Mamatha K, Manu Kanjoormana Aryan, Prathibha Prabhakaran, Johannah Natinga Mulakal, Syam Das S, Krishnakumar Im

Front Allergy· October 2024

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Review: bioavailability and efficacy of 'free' curcuminoids from curcumagalactomannoside (CGM) curcumin formulation.
Cristina Matthewman, I M Krishnakumar, Andrew G Swick

Nutr Res Rev· June 2024

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Corrigendum: A natural sustained-intestinal release formulation of red chili pepper extracted capsaicinoids (Capsifen) safely modulates energy balance and endurance performance: a randomized, double-blind, placebo-controlled study.
N Roopashree, Das S Syam, I M Krishnakumar, K N Mala, Bradley S Fleenor

Front Nutr· June 2024

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A natural sustained-intestinal release formulation of red chili pepper extracted capsaicinoids (Capsifen®) safely modulates energy balance and endurance performance: a randomized, double-blind, placebo-controlled study.
N Roopashree, Das S Syam, I M Krishnakumar, K N Mala, Bradley S Fleenor

Front Nutr· March 2024

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Enhanced bioavailability and pharmacokinetics of a novel hybrid-hydrogel formulation of fisetin orally administered in healthy individuals: a randomised double-blinded comparative crossover study.
Illathu Madhavamenon Krishnakumar, Asha Jaja-Chimedza, Ashil Joseph, Abhilash Balakrishnan, Balu Maliakel

J Nutr Sci· February 2024

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Corrigendum: Exploring the short-term influence of a proprietary oil extract of black cumin () on non-restorative sleep: a randomized, double-blinded, placebo-controlled actigraphy study.
M E Mohan, Mohind C Mohan, Prathibha Prabhakaran, S Syam Das, I M Krishnakumar

Front Nutr· February 2024

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Exploring the short-term influence of a proprietary oil extract of black cumin () on non-restorative sleep: a randomized, double-blinded, placebo-controlled actigraphy study.
M E Mohan, Mohind C Mohan, Prathibha Prabhakaran, S Syam Das, I M Krishnakumar

Front Nutr· January 2024

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Influence of CurQfen-curcumin on cognitive impairment: a randomized, double-blinded, placebo-controlled, 3-arm, 3-sequence comparative study.
S Syam Das, Prasad M Gopal, Jestin V Thomas, Mohind C Mohan, Siju C Thomas

Front Dement· September 2023

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Coconut sugar derived from coconut inflorescence sap lowers systolic blood pressure and arterial stiffness in middle-aged and older adults: a pilot study.
Nicholas A Carlini, Spencer Romanowski, Emily N Rabalais, Brandon M Kistler, Marilyn S Campbell

J Appl Physiol (1985)· March 2023

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Brain regional pharmacokinetics following the oral administration of curcumagalactomannosides and its relation to cognitive function.
Ramalingam G Kannan, Maliakal B Abhilash, Kumar Dinesh, Das S Syam, Maliakel Balu

Nutr Neurosci· September 2022

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The effects of oral administration of curcumin-galactomannan complex on brain waves are consistent with brain penetration: a randomized, double-blinded, placebo-controlled pilot study.
Aman Khanna, Syam Das S, R Kannan, Andrew G Swick, Cristina Matthewman

Nutr Neurosci· June 2022

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Natural self-emulsifying reversible hybrid-hydrogel delivery (N'SERH) of tocopherol enhances bioavailability and modulates alcohol-induced reproductive toxicity in rats.
K U Vismaya, T N Noorjasmine, S Syam Das, Lakshmi Kesavan, P S Baby Chakrapani

Andrologia· March 2022

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Surface-engineered liposomal particles of calcium ascorbate with fenugreek galactomannan enhanced the oral bioavailability of ascorbic acid: a randomized, double-blinded, 3-sequence, crossover study.
Ashil Joseph, Dinesh Kumar, Abhilash Balakrishnan, Prasanth Shanmughan, Balu Maliakel, Krishnakumar Im

RSC Adv· November 2021

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Amelioration of Radiation-Induced Damages in Mice by Curcuminoids: The Role of Bioavailability.
Vijayasteltar B Liju, Angel Thomas, Syam Das Sivadasan, Ramadasan Kuttan, Balu Maliakel, Krishnakumar Im

Nutr Cancer· August 2021

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Curcumin-Galactomannoside Complex inhibits the Proliferation of Human Cervical Cancer Cells: Possible Role in Cell Cycle Arrest and Apoptosis.
Ratheesh M, Svenia P Jose, Krishnakumar Im, Sandya S, Sangeeth Saji

Asian Pac J Cancer Prev· June 2021

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Safety assessment of a highly bioavailable curcumin-galactomannoside complex (CurQfen) in healthy volunteers, with a special reference to the recent hepatotoxic reports of curcumin supplements: A 90-days prospective study.
Vaibhavi Pancholi, Thozhuthum Parambil Smina, Ajaikumar B Kunnumakkara, Balu Maliakel, Illathu Madhavamenon Krishnakumar

Toxicol Rep· June 2021

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Influence of a low-dose supplementation of curcumagalactomannoside complex (CurQfen) in knee osteoarthritis: A randomized, open-labeled, active-controlled clinical trial.
Jestin V Thomas, Thozhuthum Parambil Smina, Aman Khanna, Ajaikumar B Kunnumakkara, Balu Maliakel

Phytother Res· March 2021

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Efficacy of a novel extract of fenugreek seeds in alleviating vasomotor symptoms and depression in perimenopausal women: A randomized, double-blinded, placebo-controlled study.
Aman Khanna, Febi John, Syam Das, Jestin Thomas, Jyoti Rao, Krishnakumar Im

J Food Biochem· December 2020

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Curcumagalactomannoside/Glucosamine Combination Improved Joint Health Among Osteoarthritic Subjects as Compared to Chondroitin Sulfate/Glucosamine: Double-Blinded, Randomized Controlled Study.
Aman Khanna, Sivadasan Syam Das, Thozhuthum Parambil Smina, Jestin V Thomas, Ajaikumar B Kunnumakkara

J Altern Complement Med· October 2020

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Anti-Ulcerative Effect of Curcumin-Galactomannoside Complex on Acetic Acid-Induced Experimental Model by Inhibiting Inflammation and Oxidative Stress.
S Sheethal, M Ratheesh, Svenia P Jose, S Asha, I M Krishnakumar

Inflammation· August 2020

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Safety assessment of a fenugreek dietary fiber-based formulation of capsaicinoids-rich red chili () extract (Capsifen®): Acute and sub-chronic studies.
Ashil Joseph, Johannah Nm, Suresh Kumar, Syam Das S, Balu Maliakel, Krishnakumar Im

Toxicol Rep· May 2020

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Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study.
Ratheesh Mohan, Svenia Jose, Johannah Mulakkal, Darla Karpinsky-Semper, Andrew G Swick

BMC Complement Altern Med· May 2019

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