Publications by authors named "Krishnan Mohankumar"

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Immune landscape in liver of neonatal mice with phlebotomy-induced anemia.
Balamurugan Ramatchandirin, Wenjia Wang, Marie Amalie Balamurugan, Yasemin Alnahhas, Suneetha Desiraju, Krishnan MohanKumar

Pediatr Res· September 2025

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Platelet specific knockout of integrin beta-3 (β3) reduces severity of necrotizing enterocolitis in murine neonates.
Marie Amalie Balamurugan, Balamurugan Ramatchandirin, Suneetha Desiraju, Arjun Subrramanya, Juanitaa George Raj, Krishnan MohanKumar

Front Pediatr· July 2025

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Stored RBC transfusions leads to the systemic inflammatory response syndrome in anemic murine neonates.
Balamurugan Ramatchandirin, Marie Amalie Balamurugan, Suneetha Desiraju, Yerin Chung, Boguslaw S Wojczyk, Krishnan MohanKumar

Inflamm Res· November 2024

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A Detailed Protocol for the Induction of Anemia and RBC Transfusion-associated Necrotizing Enterocolitis in Neonatal Mice.
Balamurugan Ramatchandirin, Marie Amalie Balamurugan, Suneetha Desiraju, Yerin Chung, Krishnan MohanKumar

Bio Protoc· May 2024

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Hematological changes in neonatal mice with phlebotomy-induced anemia.
Yerin Chung, Suneetha Desiraju, Kopperuncholan Namachivayam, Pierre Guzman, Ling He, Krishnan MohanKumar

Pediatr Res· December 2022

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The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor.
Jinghua Peng, Balamurugan Ramatchandirin, Yu Wang, Alexia Pearah, Kopperuncholan Namachivayam, Krishnan MohanKumar

J Biol Chem· March 2022

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Mutation-Induced Long-Range Allosteric Interactions in the Spike Protein Determine the Infectivity of SARS-CoV-2 Emerging Variants.
Jayanta Kumar Das, Bikash Thakuri, Krishnan MohanKumar, Swarup Roy, Adnan Sljoka

ACS Omega· November 2021

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Targeted inhibition of thrombin attenuates murine neonatal necrotizing enterocolitis.
Kopperuncholan Namachivayam, Krishnan MohanKumar, Darla R Shores, Sunil K Jain, Jennifer Fundora

Proc Natl Acad Sci U S A· May 2020

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Lyophilization of human amniotic fluid is feasible without affecting biological activity.
John I Coon, Sangeeta Jain, Krishna M Sepuru, Yerin Chung, Krishnan Mohankumar

Pediatr Res· April 2020

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Severe neonatal anemia increases intestinal permeability by disrupting epithelial adherens junctions.
Krishnan MohanKumar, Kopperuncholan Namachivayam, Nithya Sivakumar, Natascha G Alves, Venkataramana Sidhaye

Am J Physiol Gastrointest Liver Physiol· April 2020

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A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions.
Krishnan MohanKumar, Kopperuncholan Namachivayam, Tanjing Song, Byeong Jake Cha, Andrea Slate

Nat Commun· August 2019

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Neonatal mice with necrotizing enterocolitis-like injury develop thrombocytopenia despite increased megakaryopoiesis.
Kopperuncholan Namachivayam, Krishnan MohanKumar, Lalit Garg, Benjamin A Torres, Akhil Maheshwari

Pediatr Res· May 2017

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Cytokines and growth factors in the developing intestine and during necrotizing enterocolitis.
Krishnan MohanKumar, Kopperuncholan Namachivayam, Thao T B Ho, Benjamin A Torres, Robin K Ohls

Semin Perinatol· February 2017

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Trinitrobenzene sulfonic acid-induced intestinal injury in neonatal mice activates transcriptional networks similar to those seen in human necrotizing enterocolitis.
Krishnan MohanKumar, Kopperuncholan Namachivayam, Feng Cheng, Rays H Y Jiang, Jaime Flores-Torres

Pediatr Res· January 2017

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Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis.
Krishnan MohanKumar, Kopperuncholan Namachivayam, Kalyan C Chapalamadugu, Steven A Garzon, Muralidhar H Premkumar

Pediatr Res· June 2016

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All-Trans Retinoic Acid Induces TGF-β2 in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2.
Kopperuncholan Namachivayam, Krishnan MohanKumar, Dima Arbach, Ramasamy Jagadeeswaran, Sunil K Jain

PLoS One· May 2016

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Transforming growth factor-β2 is sequestered in preterm human milk by chondroitin sulfate proteoglycans.
Kopperuncholan Namachivayam, Hayley P Coffing, Nehru Viji Sankaranarayanan, Yingzi Jin, Krishnan MohanKumar

Am J Physiol Gastrointest Liver Physiol· August 2015

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VEGF mRNA and protein concentrations in the developing human eye.
Irene T Ma, Suzanne McConaghy, Kopperuncholan Namachivayam, Brian A Halloran, Ashish R Kurundkar, Krishnan MohanKumar

Pediatr Res· April 2015

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Amniotic fluid-borne hepatocyte growth factor protects rat pups against experimental necrotizing enterocolitis.
Sunil K Jain, Eric W Baggerman, Krishnan Mohankumar, Kopperuncholan Namachivayam, Ramasamy Jagadeeswaran

Am J Physiol Gastrointest Liver Physiol· March 2014

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Intestinal epithelial apoptosis initiates gut mucosal injury during extracorporeal membrane oxygenation in the newborn piglet.
Krishnan MohanKumar, Cheryl R Killingsworth, R Britt McIlwain, Joseph G Timpa, Ramasamy Jagadeeswaran

Lab Invest· February 2014

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Preterm human milk contains a large pool of latent TGF-β, which can be activated by exogenous neuraminidase.
Kopperuncholan Namachivayam, Cynthia L Blanco, Brandy L Frost, Aaron A Reeves, Ramasamy Jagadeeswaran, Krishnan MohanKumar

Am J Physiol Gastrointest Liver Physiol· June 2013

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Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis.
Kopperuncholan Namachivayam, Cynthia L Blanco, Krishnan MohanKumar, Ramasamy Jagadeeswaran, Margarita Vasquez

Am J Physiol Gastrointest Liver Physiol· January 2013

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Gut mucosal injury in neonates is marked by macrophage infiltration in contrast to pleomorphic infiltrates in adult: evidence from an animal model.
Krishnan MohanKumar, Niroop Kaza, Ramasamy Jagadeeswaran, Steven A Garzon, Anchal Bansal

Am J Physiol Gastrointest Liver Physiol· July 2012

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Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling.
Jaideep Honavar, Andrey A Samal, Kelley M Bradley, Angela Brandon, Joann Balanay, Krishnan MohanKumar

Am J Respir Cell Mol Biol· August 2011

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