Publications by authors named "Krishnendu Roy"

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Automated vertical wheel bioreactor integrated with process analytics for T-cell manufacturing.
Bryan Wang, Bharat Kanwar, Annie C Bowles-Welch, Walker Byrnes, Paloma Casteleiro Costa, Krishnendu Roy

Cytotherapy· December 2025

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Label-free in-line characterization of immune cell culture using quantitative phase imaging.
Caroline E Serafini, Viswanath Gorti, Paloma Casteleiro Costa, Aaron D Silva Trenkle, Bharat Kanwar, Krishnendu Roy

NPJ Regen Med· November 2025

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An immune-competent lung-on-a-chip for modelling the human severe influenza infection response.
Rachel Ringquist, Eshant Bhatia, Paramita Chatterjee, Drishti Maniar, Zhou Fang, Krishnendu Roy

Nat Biomed Eng· September 2025

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Multi-omics integration at cell type resolution uncovers gene-metabolite mechanisms underlying osteoarthritis heterogeneity.
Abhishek Ojha, Paramita Chatterjee, Linda E Kippner, Hazel Y Stevens, Scott D Boden, Krishnendu Roy

bioRxiv· September 2025

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Single-cell transcriptomic analysis identifies systemic immunosuppressive myeloid cells and local monocytes/macrophages as key regulators in polytrauma-induced immune dysregulation.
Drishti Maniar, M Cole Keenum, Casey E Vantucci, Tyler Guyer, Paramita Chatterjee, Krishnendu Roy

Bone Res· July 2025

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Sphingomyelinase Licensing of Mesenchymal Stromal Cells Alters Lipid and Protein Metabolites for Immunomodulation.
S'Dravious A DeVeaux, Daniel C Shah, Keji Rui, Nathan F Chiappa, Hongmanlin Zhang, Krishnendu Roy

bioRxiv· July 2025

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Multi-niche human bone marrow on-a-chip for studying the interactions of adoptive CAR-T cell therapies with multiple myeloma.
Delta Ghoshal, Ingrid Petersen, Rachel Ringquist, Liana Kramer, Eshant Bhatia, Krishnendu Roy

Biomaterials· May 2025

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On-chip 3D potency assay for prediction of clinical outcomes for cell therapy candidates for osteoarthritis.
Rebecca S Schneider, Elisa B Nieves, Bhavay Aggarwal, Annie C Bowles-Welch, Hazel Y Stevens, Krishnendu Roy

Nat Commun· May 2025

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Acute diacylglycerol production activates critical membrane-shaping proteins leading to mitochondrial tubulation and fission.
Joshua G Pemberton, Krishnendu Roy, Yeun Ju Kim, Tara D Fischer, Vijay Joshi

Nat Commun· March 2025

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Human immune organoids to decode B cell response in healthy donors and patients with lymphoma.
Zhe Zhong, Manuel Quiñones-Pérez, Zhonghao Dai, Valeria M Juarez, Eshant Bhatia, Krishnendu Roy

Nat Mater· February 2025

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Corrigendum to Real-time semantic segmentation and anomaly detection of functional images for cell therapy manufacturing Cytotherapy 25 (2023) 1361 - 1369.
Rui Qi Chen, Benjamin Joffe, Paloma Casteleiro Costa, Caroline Serafini, Bryan Wang, Krishnendu Roy

Cytotherapy· January 2025

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A Dual-Adjuvanted Parenteral-Intranasal Subunit Nanovaccine generates Robust Systemic and Mucosal Immunity Against SARS-CoV-2 in Mice.
Bhawana Pandey, Zhengying Wang, Angela Jimenez, Eshant Bhatia, Ritika Jain, Krishnendu Roy

Adv Sci (Weinh)· December 2024

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Interfacing data science with cell therapy manufacturing: where we are and where we need to be.
Bryan Wang, Rui Qi Chen, Jing Li, Krishnendu Roy

Cytotherapy· September 2024

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Dimensionality-Tailored Ferromagnetism in Quasi-Two-Dimensional MnSe for the Magnetoelectrochemical Hydrogen Evolution Reaction in Alkaline Media.
Krishnendu Roy, Raktim Datta, Soumyajit Maitra, Praveen Kumar

ACS Nano· September 2024

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Single-cell transcriptome and crosstalk analysis reveals immune alterations and key pathways in the bone marrow of knee OA patients.
Paramita Chatterjee, Hazel Y Stevens, Linda E Kippner, Annie C Bowles-Welch, Hicham Drissi, Krishnendu Roy

iScience· September 2024

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Multi-Niche Human Bone Marrow On-A-Chip for Studying the Interactions of Adoptive CAR-T Cell Therapies with Multiple Myeloma.
Delta Ghoshal, Ingrid Petersen, Rachel Ringquist, Liana Kramer, Eshant Bhatia, Krishnendu Roy

bioRxiv· April 2024

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Author Correction: Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial.
Ken Mautner, Michael Gottschalk, Scott D Boden, Alison Akard, Won C Bae, Krishnendu Roy

Nat Med· March 2024

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Real-time semantic segmentation and anomaly detection of functional images for cell therapy manufacturing.
Rui Qi Chen, Benjamin Joffe, Paloma Casteleiro Costa, Caroline Filan, Bryan Wang, Krishnendu Roy

Cytotherapy· December 2023

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Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial.
Ken Mautner, Michael Gottschalk, Scott D Boden, Alison Akard, Won C Bae, Krishnendu Roy

Nat Med· December 2023

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Lattice strain induced d-band centre engineering enabled pseudocapacitive energy storage in 2D hypo-hyper electronic V-NiCoO for asymmetric supercapacitors.
Soumyajit Maitra, Krishnendu Roy, Dibyendu Ghosh, Praveen Kumar

Nanoscale· November 2023

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Early detection and metabolic pathway identification of T cell activation by in-process intracellular mass spectrometry.
Austin L Culberson, Annie C Bowles-Welch, Bryan Wang, Peter A Kottke, Angela C Jimenez, Krishnendu Roy

Cytotherapy· September 2023

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Exogenous DNA enhances DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway.
Stephen L Wang, Yongzhong Wu, Mariam Konaté, Jiamo Lu, David Mallick, Krishnendu Roy

Free Radic Biol Med· August 2023

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Single-cell epitope-transcriptomics reveal lung stromal and immune cell response kinetics to nanoparticle-delivered RIG-I and TLR4 agonists.
M Cole Keenum, Paramita Chatterjee, Alexandra Atalis, Bhawana Pandey, Angela Jimenez, Krishnendu Roy

Biomaterials· June 2023

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Mesenchymal stromal cells for bone trauma, defects, and disease: Considerations for manufacturing, clinical translation, and effective treatments.
Annie C Bowles-Welch, Angela C Jimenez, Hazel Y Stevens, David A Frey Rubio, Linda E Kippner, Krishnendu Roy

Bone Rep· June 2023

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A multiadjuvant polysaccharide-amino acid-lipid (PAL) subunit nanovaccine generates robust systemic and lung-specific mucosal immune responses against SARS-CoV-2 in mice.
Bhawana Pandey, Zhengying Wang, Angela Jimenez, Eshant Bhatia, Ritika Jain, Krishnendu Roy

bioRxiv· May 2023

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