Publications by authors named "Kristin Calar"

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Recapitulating physiologically relevant oxygen levels and extracellular matrix remodeling in patient-derived tumor-immune tunable models reveal targeting opportunities for immunologically cold high-grade serous tumors.
Simona Plesselova, Hailey Axemaker, Kristin Calar, Oduduabasi Isaiah, Jared Wollman

bioRxiv· June 2025

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Reprogramming of normal fibroblasts into ovarian cancer-associated fibroblasts via non-vesicular paracrine signaling induces an activated fibroblast phenotype.
Hailey Axemaker, Simona Plesselova, Kristin Calar, Megan Jorgensen, Jared Wollman

Biochim Biophys Acta Mol Cell Res· October 2024

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Multicompartmentalized Microvascularized Tumor-on-a-Chip to Study Tumor-Stroma Interactions and Drug Resistance in Ovarian Cancer.
Simona Plesselova, Kristin Calar, Hailey Axemaker, Emma Sahly, Amrita Bhagia

Cell Mol Bioeng· October 2024

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Multicompartmentalized microvascularized tumor-on-a-chip to study tumor-stroma interactions and drug resistance in ovarian cancer.
Simona Plesselova, Kristin Calar, Hailey Axemaker, Emma Sahly, Pilar de la Puente

bioRxiv· June 2024

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Normal Uterine Fibroblast Are Reprogramed into Ovarian Cancer-Associated Fibroblasts by Ovarian Tumor-derived Conditioned Media.
Hailey Axemaker, Simona Plesselova, Kristin Calar, Megan Jorgensen, Jared Wollman

bioRxiv· October 2023

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The WNK1-ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib.
Adrián Sánchez-Fdez, Sofía Matilla-Almazán, Juan Carlos Montero, Sofía Del Carmen, Mar Abad, Kristin Calar

Clin Transl Med· April 2023

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Reduction of Metastasis via Epigenetic Modulation in a Murine Model of Metastatic Triple Negative Breast Cancer (TNBC).
Jessica L S Zylla, Mariah M Hoffman, Simona Plesselova, Somshuvra Bhattacharya, Kristin Calar

Cancers (Basel)· March 2022

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Bioengineering the Oxygen-Deprived Tumor Microenvironment Within a Three-Dimensional Platform for Studying Tumor-Immune Interactions.
Somshuvra Bhattacharya, Kristin Calar, Claire Evans, Mark Petrasko, Pilar de la Puente

Front Bioeng Biotechnol· September 2020

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Human Plasma-Derived 3D Cultures Model Breast Cancer Treatment Responses and Predict Clinically Effective Drug Treatment Concentrations.
Kristin Calar, Simona Plesselova, Somshuvra Bhattacharya, Megan Jorgensen, Pilar de la Puente

Cancers (Basel)· June 2020

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Mimicking tumor hypoxia and tumor-immune interactions employing three-dimensional in vitro models.
Somshuvra Bhattacharya, Kristin Calar, Pilar de la Puente

J Exp Clin Cancer Res· May 2020

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Analysis of Dual Class I Histone Deacetylase and Lysine Demethylase Inhibitor Domatinostat (4SC-202) on Growth and Cellular and Genomic Landscape of Atypical Teratoid/Rhabdoid.
Mariah M Hoffman, Jessica S Zylla, Somshuvra Bhattacharya, Kristin Calar, Timothy W Hartman

Cancers (Basel)· March 2020

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