Publications by authors named "Kristina M Cook"

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Metabolic reprogramming in diffuse intrinsic pontine gliomas (DIPG): dual inhibition of mitochondrial oxidative phosphorylation and lactate metabolism to enhance anti-tumor and radiosensitizing effects in DIPG cells.
Han Shen, Quy-Susan Huynh, Faiqa Mudassar, Cecilia Chang, Brian Gloss, Kristina M Cook

Cancer Metab· October 2025

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Inhibition of mitochondrial bioenergetics and hypoxia to radiosensitize diffuse intrinsic pontine glioma.
Han Shen, Faiqa Mudassar, Shiyong Ma, Xingyu Wang, Sandy Nguyen, Kristina M Cook

Neuro Oncol· May 2025

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An mRNA-display derived cyclic peptide scaffold reveals the substrate binding interactions of an N-terminal cysteine oxidase.
Yannasittha Jiramongkol, Karishma Patel, Jason Johansen-Leete, Joshua W C Maxwell, Yiqun Chang, Kristina M Cook

Nat Commun· May 2025

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The enzymatic oxygen sensor cysteamine dioxygenase binds its protein substrates through their N-termini.
Karishma Patel, Yannasittha Jiramongkol, Alexander Norman, Joshua W C Maxwell, Biswaranjan Mohanty, Kristina M Cook

J Biol Chem· September 2024

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Monitoring the sleep health of adults: a scoping review of routine national surveillance systems.
Joshua A H Way, Seren Ucak, Chloe-Anne Martinez, Kate Sutherland, Kristina M Cook

Sleep Adv· August 2024

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Correction: Overexpression of VIRMA confers vulnerability to breast cancers via the mA-dependent regulation of unfolded protein response.
Quintin Lee, Renhua Song, Dang Anh Vu Phan, Natalia Pinello, Jessica Tieng, Kristina M Cook

Cell Mol Life Sci· July 2023

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Overexpression of VIRMA confers vulnerability to breast cancers via the mA-dependent regulation of unfolded protein response.
Quintin Lee, Renhua Song, Dang Anh Vu Phan, Natalia Pinello, Jessica Tieng, Kristina M Cook

Cell Mol Life Sci· May 2023

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Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation.
Chloe-Anne Martinez, Yannasittha Jiramongkol, Neha Bal, Imala Alwis, Polina E Nedoboy, Kristina M Cook

J Biol Chem· November 2022

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Improving the synergistic combination of programmed death-1/programmed death ligand-1 blockade and radiotherapy by targeting the hypoxic tumour microenvironment.
Faiqa Mudassar, Han Shen, Kristina M Cook, Eric Hau

J Med Imaging Radiat Oncol· June 2022

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Targeting Glucose Metabolism of Cancer Cells with Dichloroacetate to Radiosensitize High-Grade Gliomas.
Kristina M Cook, Han Shen, Kelly J McKelvey, Harriet E Gee, Eric Hau

Int J Mol Sci· July 2021

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A zebrafish model of tuberculosis comorbidity and the effects of HIF-activating intervention.
Stefan H Oehlers, Elinor Hortle, Kristina M Cook

FEBS J· September 2020

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Out of breath, out of time: interactions between HIF and circadian rhythms.
Emma J O'Connell, Chloe-Anne Martinez, Yichuan G Liang, Peter A Cistulli, Kristina M Cook

Am J Physiol Cell Physiol· September 2020

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C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway.
Nalin Kataria, Chloe-Anne Martinez, Bernadette Kerr, Samantha S Zaiter, Monica Morgan, Kristina M Cook

Cell Physiol Biochem· December 2019

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The Cancer Clock Is (Not) Ticking: Links between Circadian Rhythms and Cancer.
Monica N Morgan, Sapir Dvuchbabny, Chloe-Anne Martinez, Bernadette Kerr, Peter A Cistulli, Kristina M Cook

Clocks Sleep· December 2019

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Determining the Redox Potential of a Protein Disulphide Bond.
Kristina M Cook

Methods Mol Biol· November 2019

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A Cell Culture Model that Mimics Physiological Tissue Oxygenation Using Oxygen-permeable Membranes.
Chloe-Anne Martinez, Peter A Cistulli, Kristina M Cook

Bio Protoc· September 2019

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Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells.
Chloe-Anne Martinez, Bernadette Kerr, Charley Jin, Peter A Cistulli, Kristina M Cook

Int J Mol Sci· January 2019

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Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer.
Imre Hunyor, Kristina M Cook

Am J Physiol Regul Integr Comp Physiol· October 2018

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Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models.
Emily M Harris, Jonathan D Strope, Shaunna L Beedie, Phoebe A Huang, Andrew K L Goey, Kristina M Cook

Mar Drugs· July 2018

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Autoregulation of von Willebrand factor function by a disulfide bond switch.
Diego Butera, Freda Passam, Lining Ju, Kristina M Cook, Heng Woon

Sci Adv· February 2018

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Zinc is a potent and specific inhibitor of IFN-λ3 signalling.
Scott A Read, Kate S O'Connor, Vijay Suppiah, Chantelle L E Ahlenstiel, Stephanie Obeid, Kristina M Cook

Nat Commun· May 2017

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A substrate-driven allosteric switch that enhances PDI catalytic activity.
Roelof H Bekendam, Pavan K Bendapudi, Lin Lin, Partha P Nag, Jun Pu, Kristina M Cook

Nat Commun· August 2016

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Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction.
Andrew K L Goey, Cindy H Chau, Tristan M Sissung, Kristina M Cook, David J Venzon

J Nat Prod· May 2016

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Inhibition of the HIF1α-p300 interaction by quinone- and indandione-mediated ejection of structural Zn(II).
Madura K P Jayatunga, Sam Thompson, Tawnya C McKee, Mun Chiang Chan, Kelie M Reece, Kristina M Cook

Eur J Med Chem· April 2015

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Structural Elucidation and Synthesis of Eudistidine A: An Unusual Polycyclic Marine Alkaloid that Blocks Interaction of the Protein Binding Domains of p300 and HIF-1α.
Susanna T S Chan, Paresma R Patel, Tanya R Ransom, Curtis J Henrich, Tawnya C McKee, Kristina M Cook

J Am Chem Soc· April 2015

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