Publications by authors named "Kristopher D Rawls"

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Identifying metabolic adaptations characteristic of cardiotoxicity using paired transcriptomics and metabolomics data integrated with a computational model of heart metabolism.
Bonnie V Dougherty, Connor J Moore, Kristopher D Rawls, Matthew L Jenior, Bryan Chun

PLoS Comput Biol· February 2024

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Identifying functional metabolic shifts in heart failure with the integration of omics data and a heart-specific, genome-scale model.
Bonnie V Dougherty, Kristopher D Rawls, Glynis L Kolling, Kalyan C Vinnakota, Anders Wallqvist

Cell Rep· March 2021

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Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug response.
Devin G Roller, Stephen A Hoang, Kristopher D Rawls, Katherine A Owen, Michael B Simmers

Sci Rep· March 2021

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Predicting changes in renal metabolism after compound exposure with a genome-scale metabolic model.
Kristopher D Rawls, Bonnie V Dougherty, Kalyan C Vinnakota, Venkat R Pannala, Anders Wallqvist

Toxicol Appl Pharmacol· February 2021

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Genome-Scale Characterization of Toxicity-Induced Metabolic Alterations in Primary Hepatocytes.
Kristopher D Rawls, Edik M Blais, Bonnie V Dougherty, Kalyan C Vinnakota, Venkat R Pannala

Toxicol Sci· December 2019

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Mechanistic identification of biofluid metabolite changes as markers of acetaminophen-induced liver toxicity in rats.
Venkat R Pannala, Kalyan C Vinnakota, Kristopher D Rawls, Shanea K Estes, Tracy P O'Brien

Toxicol Appl Pharmacol· June 2019

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A simplified metabolic network reconstruction to promote understanding and development of flux balance analysis tools.
Kristopher D Rawls, Bonnie V Dougherty, Edik M Blais, Ethan Stancliffe, Glynis L Kolling

Comput Biol Med· February 2019

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Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions.
Edik M Blais, Kristopher D Rawls, Bonnie V Dougherty, Zhuo I Li, Glynis L Kolling

Nat Commun· February 2017

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