Publications by authors named "Kristopher Kuchenbecker"

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Scp776, A Novel IGF-1 Fusion Protein for Acute Therapy to Promote Escape From Apoptosis in Tissues Affected by Ischemic Injury: 2 Randomized Placebo-Controlled Phase 1 Studies in Healthy Adults.
Samuel J Pfaff, Terry O'Reilly, Yan Zhang, Walter Olsen, Kristopher Kuchenbecker

Clin Pharmacol Drug Dev· January 2025

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Development of 5N-Bicalutamide, a High-Affinity Reversible Covalent Antiandrogen.
Felipe de Jesus Cortez, Phuong Nguyen, Charles Truillet, Boxue Tian, Kristopher M Kuchenbecker

ACS Chem Biol· December 2017

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Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism.
Idelisse Ortiz Torres, Kristopher M Kuchenbecker, Chimno I Nnadi, Robert J Fletterick, Mark J S Kelly

Nat Commun· February 2015

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The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1.
Raymond D Blind, Elena P Sablin, Kristopher M Kuchenbecker, Hsiu-Ju Chiu, Ashley M Deacon

Proc Natl Acad Sci U S A· October 2014

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Design of a photoswitchable cadherin.
Ryan S Ritterson, Kristopher M Kuchenbecker, Michael Michalik, Tanja Kortemme

J Am Chem Soc· August 2013

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The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals.
Lisa C Watson, Kristopher M Kuchenbecker, Benjamin J Schiller, John D Gross, Miles A Pufall

Nat Struct Mol Biol· July 2013

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Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer.
Dawn T Bravo, Yi-Lin Yang, Kristopher Kuchenbecker, Ming-Szu Hung, Zhidong Xu

BMC Cancer· July 2013

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Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly.
Daniele Canzio, Evelyn Y Chang, Smita Shankar, Kristopher M Kuchenbecker, Matthew D Simon

Mol Cell· January 2011

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Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma.
Junichi Okamoto, Iwao Mikami, Yuichi Tominaga, Kristopher M Kuchenbecker, Yu-Ching Lin

J Thorac Oncol· October 2008

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Inhibition of Wnt-2 and galectin-3 synergistically destabilizes beta-catenin and induces apoptosis in human colorectal cancer cells.
Yihui Shi, Biao He, Kristopher M Kuchenbecker, Liang You, Zhidong Xu

Int J Cancer· September 2007

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Wnt inhibitory factor-1 gene transfer inhibits melanoma cell growth.
Yu-Ching Lin, Liang You, Zhidong Xu, Biao He, Cheng-Ta Yang, Kristopher Kuchenbecker

Hum Gene Ther· April 2007

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Stathmin is overexpressed in malignant mesothelioma.
Jae Y Kim, Chansonette Harvard, Liang You, Zhidong Xu, Kristopher Kuchenbecker

Anticancer Res· March 2007

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Wnt inhibitory factor-1, a Wnt antagonist, is silenced by promoter hypermethylation in malignant pleural mesothelioma.
Sonny Batra, Yihui Shi, Kristopher M Kuchenbecker, Biao He, Noemi Reguart

Biochem Biophys Res Commun· April 2006

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Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines.
Yu-Ching Lin, Liang You, Zhidong Xu, Biao He, Iwao Mikami, Kristopher Kuchenbecker

Biochem Biophys Res Commun· March 2006

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