Publications by authors named "Kuanglei Wang"

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The current strategies of optimization of oseltamivir against mutant neuraminidases of influenza A：A review.
Kuanglei Wang, Huicong Zhang, Yongshou Tian

Eur J Med Chem· December 2022

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Discovery of hydrazide-containing oseltamivir analogues as potent inhibitors of influenza A neuraminidase.
Hongqian Zhao, Siyuan Jiang, Zhifan Ye, Hongxi Zhu, Baichun Hu, Kuanglei Wang, Jun Wang

Eur J Med Chem· October 2021

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Discovery of a non-zwitterionic oseltamivir analogue as a potent influenza a neuraminidase inhibitor.
Huicong Zhang, Kuanglei Wang, Hongxi Zhu, Xiaodi Zhao, Hongqian Zhao, Jian Wang

Eur J Med Chem· August 2020

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Application of carbamyl in structural optimization.
Kuanglei Wang, Hongxi Zhu, Hongqian Zhao, Kun Zhang, Yongshou Tian

Bioorg Chem· May 2020

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Design, synthesis and biological evaluation of oseltamivir derivatives containing pyridyl group as potent inhibitors of neuraminidase for influenza A.
Kuanglei Wang, Zaiqiang Lei, Lei Zhao, Binfeng Chen, Fei Yang

Eur J Med Chem· January 2020

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Design, synthesis, and evaluation of carboxyl-modified oseltamivir derivatives with improved lipophilicity as neuraminidase inhibitors.
Boyu Wang, Kuanglei Wang, Peipei Meng, Yaping Hu, Fei Yang

Bioorg Med Chem Lett· November 2018

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Striking a Balance between Carbonate/Carbamate Linkage Bond- and Reduction-Sensitive Disulfide Bond-Bearing Linker for Tailored Controlled Release: In Situ Covalent-Albumin-Binding Gemcitabine Prodrugs Promote Bioavailability and Tumor Accumulation.
Huicong Zhang, Kuanglei Wang, Kexin Na, Dan Li, Zhenbao Li, Menglin Wang

J Med Chem· June 2018

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Multifunctional Tumor-Targeting Cathepsin B-Sensitive Gemcitabine Prodrug Covalently Targets Albumin in Situ and Improves Cancer Therapy.
Huicong Zhang, Zhisu Sun, Kuanglei Wang, Na Li, Hongxiang Chen

Bioconjug Chem· June 2018

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Synthesis and biological evaluation of NH-acyl oseltamivir analogues as potent neuraminidase inhibitors.
Kuanglei Wang, Fei Yang, Lihui Wang, Kemin Liu, Lu Sun, Boyu Wang

Eur J Med Chem· December 2017

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A gene delivery system containing nuclear localization signal: Increased nucleus import and transfection efficiency with the assistance of RanGAP1.
Kang Chen, Lingling Guo, Jiulong Zhang, Qing Chen, Kuanglei Wang

Acta Biomater· January 2017

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Synthesis and characterization of a PAMAM-OH derivative containing an acid-labile β-thiopropionate bond for gene delivery.
Kang Chen, Qing Chen, Kuanglei Wang, Jia Zhu, Weinan Li

Int J Pharm· July 2016

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