Publications by authors named "Kwang-Hee Shin"

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Validated LC-MS/MS method for cisplatin quantification in plasma, whole blood, and cervical cancer tissue via diethyldithiocarbamate derivatization: Clinical application in cervical cancer.
Honghao Bai, Min-Gyo Seo, Seo-Yeon Choi, Vipada Khaowroongrueng, Yoon-Jee Chae, Kwang-Hee Shin

J Pharm Biomed Anal· January 2026

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Fetal outcomes of antiseizure medication use during pregnancy: A nationwide retrospective cohort study.
Minji Seo, Sumin Park, Tae-Eun Kim, Kyeong Eun Lee, Pan-Woo Ko, Kwang-Hee Shin

Epilepsia· December 2025

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Optimizing Venlafaxine Therapy in Pregnancy: A Maternal-Fetal PBPK Modeling Approach.
Seo-Yeon Choi, Eunsol Yang, Kwang-Hee Shin

Drug Des Devel Ther· November 2025

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Escitalopram Dose Optimization During Pregnancy: A PBPK Modeling Approach.
Seo-Yeon Choi, Eunsol Yang, Kwang-Hee Shin

Pharmaceutics· October 2025

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Identification of biomarkers in gynecologic cancers: a machine learning approach for metabolomics.
SangHun Cha, Sang-Min Lee, Kyeong Eun Lee, Min-Gul Kim, Sun-Young Lee, Kwang-Hee Shin

Transl Clin Pharmacol· September 2025

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Application of Real-World Evidence to Support FDA Regulatory Decision Making.
Vipada Khaowroongrueng, Tae-Eun Kim, Sang-In Park, Kwang-Hee Shin

AAPS J· May 2025

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Research on unintroduced new drugs in South Korea from 2011 to 2020: approaches to prioritization and strategy.
Hyewon Jeon, Sang-In Park, Sang-Won Lee, Tae-Eun Kim, Kwang-Hee Shin

Transl Clin Pharmacol· December 2024

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Population pharmacokinetic modeling of sufentanil in adult Korean patients undergoing cardiopulmonary bypass surgery.
Vipada Khaowroongrueng, Kuk Hui Son, Sang-Min Lee, JiYeon Lee, Chun-Gon Park, Dongseong Shin, Kwang-Hee Shin

CPT Pharmacometrics Syst Pharmacol· October 2024

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Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials.
Kwang-Hee Shin, Hye Duck Choi

Int J Clin Pharmacol Ther· June 2024

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Metabolomic Profiles in Patients with Cervical Cancer Undergoing Cisplatin and Radiation Therapy.
Seo-Yeon Choi, Suin Kim, Ji-Young Jeon, Min-Gul Kim, Sun-Young Lee, Kwang-Hee Shin

Biomol Ther (Seoul)· May 2024

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Profiling of endogenous metabolites and changes in intestinal microbiota distribution after GEN-001 () administration.
Min-Gul Kim, Suin Kim, Ji-Young Jeon, Seol Ju Moon, Yong-Geun Kwak, Kwang-Hee Shin

Korean J Physiol Pharmacol· March 2024

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Application of tree-based machine learning classification methods to detect signals of fluoroquinolones using the Korea Adverse Event Reporting System (KAERS) database.
Min-Gyo Jang, SangHun Cha, Seunghwak Kim, Sojung Lee, Kyeong Eun Lee, Kwang-Hee Shin

Expert Opin Drug Saf· November 2023

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Strong inhibition of organic cation transporter 2 by flavonoids and attenuation effects on cisplatin-induced cytotoxicity.
Kwang-Hee Shin, Kyeong-Ryoon Lee, Min-Ji Kang, Yoon-Jee Chae

Chem Biol Interact· July 2023

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Drug-Drug interactions of docetaxel in patients with breast cancer based on insurance claims data.
Kwang-Hee Shin, Young-Mi Ah, Sang Hun Cha, Hye Duck Choi

PLoS One· June 2023

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Prediction of the Drug-Drug Interaction Potential between Tegoprazan and Amoxicillin/Clarithromycin Using the Physiologically Based Pharmacokinetic and Pharmacodynamic Model.
Zhuodu Wei, Hyeon-Cheol Jeong, Min-Gul Kim, Kwang-Hee Shin

Pharmaceuticals (Basel)· February 2023

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Predicting the systemic exposure and lung concentration of nafamostat using physiologically-based pharmacokinetic modeling.
Hyeon-Cheol Jeong, Yoon-Jee Chae, Kwang-Hee Shin

Transl Clin Pharmacol· December 2022

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Incorporation of real-world data to a clinical trial: use of external controls.
Tae-Eun Kim, Sang-In Park, Kwang-Hee Shin

Transl Clin Pharmacol· September 2022

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A compatibility evaluation between the physiologically based pharmacokinetic (PBPK) model and the compartmental PK model using the lumping method with real cases.
Hyo-Jeong Ryu, Won-Ho Kang, Taeheon Kim, Jae Kyoung Kim, Kwang-Hee Shin

Front Pharmacol· August 2022

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Comparison of Efficacy and Safety of Statin-Ezetimibe Combination Therapy with Statin Monotherapy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Studies.
Kwang-Hee Shin, Hye Duck Choi

Am J Cardiovasc Drugs· July 2022

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Integration of a Physiologically Based Pharmacokinetic and Pharmacodynamic Model for Tegoprazan and Its Metabolite: Application for Predicting Food Effect and Intragastric pH Alterations.
Hyeon-Cheol Jeong, Min-Gul Kim, Zhuodu Wei, Kyeong-Ryoon Lee, Jaehyeok Lee, Kwang-Hee Shin

Pharmaceutics· June 2022

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Bioanalytical methods for the detection of duloxetine and thioctic acid in plasma using ultra performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS).
Zhuodu Wei, Hyeon-Cheol Jeong, Ye-Ji Kang, Jaesang Jang, Myoung-Hwan Kim, Kwang-Hee Shin

Transl Clin Pharmacol· June 2022

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Determination of candesartan or olmesartan in hypertensive patient plasma using UPLC-MS/MS.
Hyeon-Cheol Jeong, Yo-Han Seo, Namyi Gu, Moo Yong Rhee, Kwang-Hee Shin

Transl Clin Pharmacol· December 2021

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Prediction of Fluoxetine and Norfluoxetine Pharmacokinetic Profiles Using Physiologically Based Pharmacokinetic Modeling.
Hyeon-Cheol Jeong, Yoon-Jee Chae, Sooyeun Lee, Wonku Kang, Hwi-Yeol Yun, Kwang-Hee Shin

J Clin Pharmacol· November 2021

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Urinary Metabolomic Profiling after Administration of Corydalis Tuber and Pharbitis Seed Extract in Healthy Korean Volunteers.
Hyeon-Cheol Jeong, Jung Eun Park, Yohan Seo, Min-Gul Kim, Kwang-Hee Shin

Pharmaceutics· April 2021

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Physiologically-based pharmacokinetic model for clozapine in Korean patients with schizophrenia.
Joomi Lee, Min-Gul Kim, Hyeon-Cheol Jeong, Kwang-Hee Shin

Transl Clin Pharmacol· March 2021

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